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There has recently been a huge interest in CBD oil for its many therapeutic benefits. In this video, we will go through how CBD oil actually works. So how does THC and CBD work and why does THC have psychoactive effects and CBD doesn’t. Well in the body, we have the endocannabinoid system. This consists of two G-protein-coupled receptors called cannabinoid type 1 receptors and cannabinoid type 2 receptors. CB1 receptors are found in the central and peripheral nervous system with most of them being in the hippocampus and amygdala in the brain. So CB1 receptors are primarily found in the brain and mainly effect mood. CB2 receptors are found in our immune cells, lymphoid tissue and peripheral nerve terminals. So CB2 receptors are primarily found in the body and mainly effect the immune system and inflammation... Used to make this video: Apple macbook pro: https://amzn.to/2NltFRw Microphone used: https://amzn.to/2zCQX34 Whiteboard Biology covers the biology of different topics whilst incorporating the latest research and scientific articles. Not everyone has time, access or background information to understand the latest scientific articles and so this channels' goal is to do all the hard work and put that information into a short and 'to the point' video. If you enjoy this video and would like to stay updated with the latest content, please subscribe to the channel. Thank you!
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Cannabis is a well known drug which is known to alter the mind and body. It is also known as “pot”, “weed”, “ganja”, “marijuana” and many other slang terms. In this video, we have provided details on the composition of cannabis, its short and long term effects on brain and body, its advantages and disadvantages in medical and recreational, and its effect on individuals with different mental disorders. The video is intended to educate the general public about cannabis use and its effects. It is not intended to harm anyone’s emotions who is currently dealing with cannabis use problems. It is advised to contact a healthcare provider in case you are experiencing any symptoms or have additional concerns. ------------------------------------ This video was made by McMaster students Shefali Verma, Shilpa Tandon, and Niki Sadat Afjeh in collaboration with the McMaster Demystifying Medicine Program. Subscribe to the McMaster Demystifying Medicine YouTube channel: https://www.youtube.com/c/DemystifyingMedicine This video is provided for general and educational information only. Please consult your health care provider for Information about your health. ------------------------------------ Copyright McMaster University 2020 ------------------------------------ #DemystifyingMedicine, #MentalHealth References: 1. Gibbs, M., Winsper, C., Marwaha, S., Gilbert, E., Broome, M., & Singh, S. P. (2015). Cannabis use and mania symptoms: a systematic review and meta-analysis. Journal of affective disorders, 171, 39–47. https://doi.org/10.1016/j.jad.2014.09.016 2. Grinspoon, Peter. “Medical Marijuana.” Harvard Health Blog, 15 Apr. 2020, www.health.harvard.edu/blog/medical-marijuana-2018011513085. 3. Hall, W., & Solowij, N. (1998). Adverse effects of cannabis. The Lancet, 352(9140), 1611-1616. Hartman, R. L., & Huestis, M. A. (2013). Cannabis effects on driving skills. Clinical chemistry, 59(3), 478–492. https://doi.org/10.1373/clinchem.2012.194381 4. Hunt, G. E., Malhi, G. S., Cleary, M., Lai, H. M., & Sitharthan, T. (2016). Prevalence of comorbid bipolar and substance use disorders in clinical settings, 1990-2015: Systematic review and meta-analysis. Journal of affective disorders, 206, 331–349. https://doi.org/10.1016/j.jad.2016.07.011 5. Kedzior, K. K., & Laeber, L. T. (2014). A positive association between anxiety disorders and cannabis use or cannabis use disorders in the general population--a meta-analysis of 31 studies. BMC psychiatry, 14, 136. https://doi.org/10.1186/1471-244X-14-136 6. Lev-Ran, S., Roerecke, M., Le Foll, B., George, T., McKenzie, K., & Rehm, J. (2014). The association between cannabis use and depression: A systematic review and meta-analysis of longitudinal studies. Psychological Medicine, 44(4), 797-810. doi:10.1017/S0033291713001438 7. Lloyd, S. L., & Striley, C. W. (2018). Marijuana Use Among Adults 50 Years or Older in the 21st Century. Gerontology & geriatric medicine, 4, 2333721418781668. https://doi.org/10.1177/2333721418781668 8. Mönckeberg B F. (2014). Los pro y contra de la legalización de la marihuana [Pros and cons of legalizing marijuana]. Revista chilena de pediatria, 85(2), 229–237. https://doi.org/10.4067/S0370-41062014000200014 9. NIDA. 2020, April 8. Is marijuana a gateway drug?. Retrieved from https://www.drugabuse.gov/publications/research-reports/marijuana/marijuana-gateway-drug on 2020, November 15 10. Regier, D. A., Farmer, M. E., Rae, D. S., Locke, B. Z., Keith, S. J., Judd, L. L., & Goodwin, F. K. (1990). Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA, 264(19), 2511–2518. 11. Statista. “Marijuana Consumption by Age Canada 2019.” Statista, 2 Sept. 2020, www.statista.com/statistics/587705/marijuana-consumption-canada-by-age/. 12. Shrivastava, A., Johnston, M., Terpstra, K., & Bureau, Y. (2014). Cannabis and psychosis: Neurobiology. Indian journal of psychiatry, 56( 1), 8–16. https://doi.org/10.4103/0019-5545.124708 13. The Ministry of Health. “Health Effects of Cannabis.” Government of Canada, 2017, www.canada.ca/content/dam/hc-sc/documents/services/campaigns/27-16-1808-Factsheet-Health- Effects-eng-web.pdf.
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