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To support me on Patreon (thank you): http://www.patreon.com/cosmicskeptic To donate to my PayPal (thank you): http://www.paypal.me/cosmicskeptic To purchase Cosmic Skeptic merchandise: https://cosmicskeptic.teemill.com/ --------------------------VIDEO NOTES-------------------------- As Joe Biden moves the United States towards the decriminalisation of cannabis, offering pardons for all previous federal offences of marijuana possession, UK Home Secretary Suella Braverman is considering taking an opposite approach for Britain, with the press reporting that she is "receptive" to calls to upgrade the legal category of the drug from class B to class A. I think this is a terrible and self-defeating move, and I wanted to make a video explaining why. -------------------------TIMESTAMPS--------------------------- 0:00 Is weed "just as harmful" as cocaine? 2:11 Is weed a "gateway" drug? 6:25 Weed is harmful to your health 11:37 Who does criminalisation benefit? ----------------------SPECIAL THANKS------------------------ As always, I would like to direct extra gratitude to my top-tier patrons: Itamar Lev Evan Allen Faraz Harsini John Early Sveline Teymour Beydoun Adam Gray Joe Dowling Dmitry C. Nolan Kent Seth Balodi Citizens of Civilization James Davis g8speedy James Davis Fuu Harahap -----------------------------CONNECT------------------------------ My Website/Blog: http://www.cosmicskeptic.com SOCIAL LINKS: Twitter: http://www.twitter.com/cosmicskeptic Facebook: http://www.facebook.com/cosmicskeptic Instagram: http://www.instagram.com/cosmicskeptic Snapchat: cosmicskeptic The Cosmic Skeptic Podcast: https://podcasts.apple.com/us/podcast/the-cosmic-skeptic-podcast/id1458675168 ----------------------------CONTACT------------------------------- Business email: [email protected] Or send me something: Alex O'Connor Po Box 1610 OXFORD OX4 9LL ENGLAND ------------------------------------------------------------------------

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This is a recording of an Industrial Sonomechanics (ISM)' live webinar event from May 13th, 2020. The presentation was made by ISM's president and Chief Scientific Officer, Dr. Alexey Peshkovsky. Key Takeaways: 1. Achieving efficient, reproducible and predictable absorption of cannabinoids into the bloodstream has been and continues to be a major obstacle in the industry. 2.Traditional and historical methods of introducing cannabis into the body have been unpredictable in terms of bioavailability, timely onset of action and safety. 3. Cannabis extracts are NOT soluble in water, therefore, edibles and similar products taken by the mouth are slow and inefficient. 4. Translucent nanoemulsions of cannabinoids solve for these deficiencies, creating a rapid, predictable and reproducible effect. 5. High-intensity ultrasound has proven to be a superior solution for producing translucent nanoemulsions that can be infused into beverages without changing their appearance. Abstract: Oral administration of cannabinoids (e.g., as edibles or gel-caps), while safer and more discreet than smoking or vaping, suffers from low bioavailability, delayed onset of action and poor reproducibility. Being insoluble in water, cannabinoids cannot undergo gastrointestinal absorption until they are incorporated into mixed micelles, which are slowly formed in the small intestine during hydrolysis of co-administered triglycerides. While this step is necessary to allow cannabinoids to migrate to the intestinal absorptive cells, it drastically delays and diminishes the efficiency and reproducibility of the absorption process. Pharmaceutical industry's most successful method for overcoming similar challenges is to formulate hydrophobic bio-actives as oil-in-water nanoemulsions, which are kinetically stable, known to provide exceptional therapeutic effects, and allow bio-actives to be absorbed rapidly and completely. This presentation will demonstrate how the same approach can be applied to the cannabis industry. Commercial-scale production of translucent cannabinoid nanoemulsions (“water-soluble” CBD and THC) requires the use of an optimized formulation and a high-intensity ultrasonic processor, resulting in stable concentrates that are readily infused into and administered as beverages without compromising their appearance (e.g., optical clarity). Since aqueous dispersions of droplets in translucent nanoemulsions closely mimic mixed micelles, they rapidly migrate to the intestinal absorptive cells, avoiding the slow in-situ micelle formation process. Preclinical pharmacokinetic study results will be presented, showing significant onset of action acceleration and bioavailability enhancement of THC administered as a translucent nanoemulsion-infused beverage. Website: https://sonomechanics.com Blog: http://blog.sonomechanics.com/blog Facebook: https://www.facebook.com/industrial.sonomechanics/ Instagram: https://www.instagram.com/industrial_sonomechanics/ Twitter: https://twitter.com/sonomechanics LinkedIn: https://www.linkedin.com/company/industrial-sonomechanics-llc/

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