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Are CBD and THC as effective as people believe — or is it mostly placebo? In this episode, we break down the latest clinical evidence on medical cannabis, exploring the real-world impact of CBD, THC, and cannabis-based therapies across conditions like cancer, chronic pain, anxiety, epilepsy, and more. With medical use on the rise globally, it’s time to separate hype from hard data. 🔍 We explore: - What randomized trials and meta-analyses actually say about effectiveness - Differences between THC and CBD in clinical use - Side effects, tolerability, and potential cognitive risks - How cannabinoids affect the brain, body, and mental health 📄 Scientific References: -Castle, R. D., Marzolf, J., Morris, M., & Bushell, W. C. (2025). Meta-analysis of medical cannabis outcomes and associations with cancer. Frontiers in Oncology, 15, 1490621. https://doi.org/10.3389/fonc.2025.1490621 - Sultan, S. R., Millar, S. A., England, T. J., & O’Sullivan, S. E. (2017). A systematic review and meta-analysis of the haemodynamic effects of cannabidiol. Frontiers in Pharmacology, 8, 81. https://doi.org/10.3389/fphar.2017.00081 - Batalla, A., Bos, J., Postma, A., & Bossong, M. G. (2021). The impact of cannabidiol on human brain function: A systematic review. Frontiers in Pharmacology, 11, 618184. https://doi.org/10.3389/fphar.2020.618184 - Leen, N. A., Kowal, M. A., Batalla, A., & Bossong, M. G. (2024). The effects of standardized cannabis products in healthy volunteers and patients: A systematic literature review. Frontiers in Pharmacology, 15, 1411631. https://doi.org/10.3389/fphar.2024.1411631 - Pagano, C., Navarra, G., Coppola, L., Avilia, G., Bifulco, M., & Laezza, C. (2022). Cannabinoids: Therapeutic use in clinical practice. International Journal of Molecular Sciences, 23(6), 3344. https://doi.org/10.3390/ijms23063344 - Pintori, N., Caria, F., De Luca, M. A., & Miliano, C. (2023). THC and CBD: Villain versus hero? Insights into adolescent exposure. International Journal of Molecular Sciences, 24(6), 5251. https://doi.org/10.3390/ijms24065251 - Borgan, F., Beck, K., Butler, E., McCutcheon, R., Veronese, M., Vernon, A., & Howes, O. D. (2019). The effects of cannabinoid 1 receptor compounds on memory: A meta-analysis and systematic review across species. Psychopharmacology. https://doi.org/10.1007/s00213-019-05283-3 - Stasiak, S. P., Hall, S. H., Nichols, J., Yaacoub, I., & Shelley, T. C. S. (2021). Examining the effects of cannabidiol (CBD) on anxiety and heart rate variability during acute stress: A randomized placebo-controlled trial. Psychopharmacology, 238(7), 1965–1977. https://doi.org/10.1007/s00213-021-05823-w - Lees, R., Hines, L. A., Hindocha, C., et al. (2023). Effect of four-week cannabidiol treatment on cognitive function: Secondary outcomes from a randomized clinical trial for cannabis use disorder. Psychopharmacology, 240(2), 337–346. https://doi.org/10.1007/s00213-022-06303-5 - Hoch, E., Hall, W., Friemel, C., et al. (2024). The risks and benefits of cannabis: A review of reviews. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-024-01880-2 - Sarris, J., Sinclair, J., Karamacoska, D., Davidson, M., & Firth, J. (2020). Medicinal cannabis for psychiatric disorders: A clinically-focused systematic review. BMC Psychiatry, 20, 24. https://doi.org/10.1186/s12888-019-2409-8 - Bilbao, A., & Spanagel, R. (2022). Medical cannabinoids: A pharmacology-based systematic review and meta-analysis for all relevant medical indications. BMC Medicine, 20, 259. https://doi.org/10.1186/s12916-022-02459-1 - Lo, L. A., Lo, C. A., Pereira, C., et al. (2024). The acute effects of cannabidiol on cognitive and psychomotor performance: A systematic review and meta-analysis of human laboratory studies. Psychopharmacology. https://doi.org/10.1038/s41386-024-01847-w - Velayudhan, L., McGoohan, K., & Bhattacharyya, S. (2021). Evaluation of THC-related neuropsychiatric symptoms among adults aged 50 years and older: A systematic review and meta-regression analysis. JAMA Network Open, 4(2), e2035913. https://doi.org/10.1001/jamanetworkopen.2020.35913 🎧 Whether you're a clinician, patient, or just curious about cannabis, this episode brings nuanced, evidence-based insights to a frequently polarized topic. ⚠️ Disclaimer: This podcast summarizes peer-reviewed scientific research for informational and educational purposes only. It does not constitute medical advice. Always consult a licensed healthcare provider before starting or changing any medication, supplement, or treatment approach. 💡 Note: Content created with support from Google’s NotebookLM. The views expressed are those of the host and do not represent the original authors or their institutions. 🔔 Don’t forget to like, subscribe, and share if you find this episode helpful! #CBD #THC #MedicalCannabis #CannabisScience #ClinicalResearch #HealthFacts #EvidenceBased #SciencePodcast
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सी बी डी (CBD) क्या आपके पालतू जानवरों के लिए सुरक्षित है? आज के इस वीडियो में हम इसी ज़रूरी सवाल का जवाब ढूंढेंगे। बहुत से पेट ओनर्स अब अपने डॉग्स और कैट्स को एन्क्सायटी, दर्द और इन्फ्लेमेशन जैसी समस्याओं के लिए CBD प्रोडक्ट्स दे रहे हैं। लेकिन क्या यह सही है? क्या इससे साइड इफेक्ट्स हो सकते हैं? और कौन से प्रोडक्ट्स सेफ हैं? इस वीडियो में आप जानेंगे: ✔ CBD क्या है और यह कैसे काम करता है ✔ पेट्स के लिए इसके संभावित फायदे और रिस्क ✔ किन बातों का ध्यान रखें जब आप अपने Pet को CBD देना चाहें ✔ वेटरिनेरियन की सलाह क्यों ज़रूरी है ✔ हाई-क्वालिटी और टेस्टेड CBD प्रोडक्ट्स कैसे चुनें 💡 अगर आप अपने Pet की Anxiety, Pain या Inflammation के लिए नेचुरल ऑप्शन खोज रहे हैं, तो ये वीडियो आपके लिए है! अगर आप भारत में सबसे अच्छा सीबीडी ऑयल ढूंढ रहे हैं, तो Cure By Design CBD Oil को ज़रूर ट्राय करें। यह एक भरोसेमंद, हाई क्वालिटी और लैब-टेस्टेड प्रोडक्ट है। खास तौर पर अगर आप पेट्स के लिए भारत में सीबीडी ऑयल ढूंढ रहे हैं, तो यह एक बेहतरीन विकल्प है। ⚠ Disclaimer: यह वीडियो केवल जानकारी देने के लिए है। किसी भी उपचार से पहले अपने वेट से सलाह ज़रूर लें। #CBDForPets #PetCare #CureByDesign #CBDOilIndia #BestCBDOilIndia #CBDForDogs #CBDBenefits #PetAnxietyRelief #NaturalPetCare #CBDForCats #HolisticPetHealth #VetApprovedCBD #IndianCBDBrand #CBDPetOil #PetWellness
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Kevin Sabet is at it again in Huffington Post trying to obfuscate the issue of rescheduling of cannabis for medical purposes. I argue it shouldn't be re-scheduled, it should be de-scheduled.
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NOTE: In my first upload of this episode there was a long pause at the beginning of the video. I removed the pause in the original video and have re-uploaded a new video with the missing information from the 1:30 - 4:00 mark. Tap below! ⤵️ https://youtu.be/IG7gZpf8Opg The fastest way to get the medical benefit from cannabis is by inhaling it. Historically, this has been done by smoking it, more recently people have chosen to vaporize as a primary method. There are differences between these two types of medical consumption, so let's talk about it! ------- Sources: https://realmofcaring.org/understanding-cannabis-smoking-vs-vaping/ ------- Please SUBSCRIBE for new videos throughout the week! https://bit.ly/3xhijVf Let's connect: Website: https://DrDavidMD.com/ FB: https://www.facebook.com/PagingDrDavidMD IG: https://www.instagram.com/pagingdrdavidmd/ LI: https://www.linkedin.com/company/drdavidmd/ TW: https://twitter.com/PagingDrDavidMD -------- Become a patron to access exclusive content. Click below: https://www.patreon.com/DrDavidMD Dr. David is an independent thinker who draws from more than 25 years of clinical experience. He relies on a broad range of evidence-based information to provide his best possible guidance. Dr. David's thoughts and opinions may shift as the data evolves. Information he shares with the public is not intended as a substitute for professional medical advice, diagnosis, or treatment. All content is informative and does not replace the need for consultation with qualified health professionals. #medicalcannabis #alternativemedicine #vaping #drdavidmd
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The Comprehensive Benefits of CBD Oil: From Anxiety to Pain Relief
What is this hype about CBD oil? Is it really a miracle cure for pain, anxiety and epilepsy? I tried CBD oil on myself for 2 weeks to see if it made a difference with my bipolar and anxiety. Apologies for the video going out of focus at times, I really do need a new camera, this one only records for 45seconds at a time without overheating. If you like and benefit from my content please consider becoming a Patron (instructions below) and together we can fight the stigma of mental health by making professional educational mental health content. References: http://journals.sagepub.com/doi/abs/10.1177/0269881110379283) https://www.ncbi.nlm.nih.gov/pubmed/18801823) WAYS TO SUPPORT THIS CHANNEL & BLOG: *Patreon: http://www.patreon.com/askmeimbipolar (You can pledge as low as a £1/month to support.) *Kit Wish List: http://amzn.eu/iBLK5tG (Purchase an item from my wish list for me to help support this channel and my adventures. Some of the items may require contacting me for shipping details. See email below.) *ONE-TIME CONTRIBUTION: -PayPal: https://www.paypal.me/KUppiah
Wonder Leaf CBD Oil: Exploring Its Unique Properties and Benefits
Learn about CBD and what CL found in its recent tests and reviews of popular CBD supplements - inlcuding oils, softgels and gummies, topicals (lotions and balms), and pet products. More details are in CL's report at https://bit.ly/33kSHK3 0:50 What is CBD 1:23 What is the cost for good CBD 2:00 Drug tests and testing positive while taking CBD 3:18 What is hemp oil 3:51 How CBD has been approved as a drug 4:28 Benefits of taking CBD 4:54 Side effects of CBD What did CL find in its 2020 tests? The lowest cost to get CBD fell by 70% compared to its last review in 2018, with the current cost to obtain an equal amount of CBD from each product ranging from from just 24 cents to $2.67 per 10 mg. There were many good-quality, lower-cost products available on the market than ConsumerLab found in the past. In addition, levels of THC (tetrahydrocannabinol, a psychoactive compound) also tended to be much lower, with THC not detectable in most products. You can become a ConsumerLab.com member now at https://bit.ly/2GQuuDR for immediate access to exclusive reviews of over 1,000 products, hundreds of CL Answers, warnings, and other information about supplements and natural products that you won't find anywhere else! Not ready to become a member yet? Sign up for our FREE newsletter https://bit.ly/3m9Faxw. #CBDoilreviews #CBDforpets #CBDtests #CBDgummies
