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Glucagon-like peptide-1 (GLP-1) is a hormone in the intestine that regulates blood sugar levels, appetite, and digestion. Increasing GLP-1 levels can be beneficial for people with diabetes, obesity, or metabolic syndrome. While medications like semaglutide and tirzepatide exist to stimulate GLP-1 production, incorporating certain foods and supplements into your diet can also naturally enhance GLP-1 secretion. In this podcast, we’ll talk about some of these foods and supplements and their potential benefits for gut health and metabolism. Soluble Fiber-Rich Foods Fiber is well-known for its numerous health benefits, including improved digestion, weight management, and blood sugar control. Certain types of fiber, such as soluble fiber, have been shown to increase GLP-1 secretion. Oats, barley, and legumes (such as beans, lentils, and chickpeas) are rich in soluble fiber. Brussels sprouts, avocados, and flaxseeds also help. Incorporating these soluble fiber-rich foods into your meals can help support healthy GLP-1 levels and promote overall gut health. Remember that soluble fiber absorbs water and creates a gel-like substance in your body. Because of this, staying hydrated and gradually increasing your fiber intake over time is important to help minimize digestive upset and constipation. Fatty Fish Fatty fish like salmon, mackerel, sardines, and trout are excellent sources of omega-3 fatty acids, which have been shown to have numerous health benefits, including improving insulin sensitivity and increasing GLP-1 secretion. Incorporating fatty fish into your diet two to three times per week can help support a healthy gut and metabolic function. Grilling, baking, or broiling fish with herbs and spices is a delicious and nutritious way to enjoy these omega-3-rich foods. Nuts and Seeds Nuts and seeds are nutrient-dense foods with various health benefits, including supporting gut health and increasing GLP-1 levels. Almonds, walnuts, chia seeds, and flaxseeds are particularly rich in fiber, healthy fats, and antioxidants that can stimulate GLP-1 secretion. Snacking on a handful of nuts or seeds, adding them to salads, yogurt, or smoothies, or using them as a topping for oatmeal or baked goods are all easy ways to incorporate these nutritious foods into your diet. Lean proteins Lean proteins can increase GLP-1 levels and help maintain muscle mass. This is helpful for people taking GLP-1 medications like semaglutide since muscle loss and body fat often occur. It’s important to offset this by eating as much lean protein as possible. Examples of lean proteins include fish, chicken, turkey, and eggs. Lean cuts of beef, cottage cheese, and tofu are also great sources of lean protein. Keep in mind: Protein may also naturally reduce your appetite. Curcumin Curcumin is the main compound found in turmeric, a spice widely used in traditional Indian cuisine and known for its potent anti-inflammatory and antioxidant properties. Studies have suggested that curcumin may decrease blood sugar and increase GLP-1 levels. However, more research is needed to fully understand the mechanisms underlying its effects on GLP-1 and its potential therapeutic applications in metabolic disorders. Yerba Mate Yerba mate is a traditional South American beverage made from the leaves of the Ilex paraguariensis plant. It is known for its stimulating effects due to its caffeine content. It also contains polyphenols and saponins, which have been studied for their potential health benefits, including fat loss and appetite reduction. Berberine Berberine is a plant-based compound found in goldenseal, barberry, and Oregon grape. It has been used in traditional Chinese medicine for centuries to treat various ailments, including digestive disorders and diabetes. Berberine has garnered attention for its ability to modulate glucose and lipid metabolism, partly through its effects on GLP-1 secretion. Thanks again for listening to The Peptide Podcast. We love having you as part of our community. If you love this podcast, please share it with your friends and family on social media, and have a happy, healthy week! We’re huge advocates of elevating your health game with nutrition, supplements, and vitamins. Whether it’s a daily boost or targeted support, we trust and use Momentous products to supercharge our wellness journey. Momentous only uses the highest-quality ingredients, and every single product is rigorously tested by independent third parties to ensure their products deliver on their promise to bring you the best supplements on the market.

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New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/ DESCRIPTION:The Standard American Diet is worsening and falls far from the CDC goals for minimal fruit and vegetable intake, with some states doing worse than others. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/sad-states-standard-american-diet-state-by-state-comparison/ and I'll try to answer it! How S.A.D. is the Standard American Diet? Check out Nation's Diet in Crisis (http://nutritionfacts.org/video/nations-diet-in-crisis/) and Calculate Your Healthy Eating Score (http://nutritionfacts.org/video/calculate-your-healthy-eating-score/). Even small tweaks can dramatically boost the antioxidant power of one's meals. See Antioxidants in a Pinch (http://nutritionfacts.org/video/antioxidants-in-a-pinch/) and A Better Breakfast (http://nutritionfacts.org/video/a-better-breakfast/). There are dozens more videos on fruits (http://nutritionfacts.org/topics/fruits/) and vegetables (http://nutritionfacts.org/topics/vegetables/) and hundreds of videos on more than a thousand other topics (http://nutritionfacts.org/topics/). Note in the Sources Cited section that all of the papers are available "open access," which means freely available to the public at no cost. Image Credit: Deimos3024 via Wikimedia Commons, and Ali Karimian, and Roco Julie via Flickr. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org

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Please Subscribe for 3x Videos Per Week https://www.youtube.com/user/TheTdelauer?sub_confirmation=1 To learn more, visit my website here: http://www.ThomasDeLauer.com Get the Apparel I Wear at http://www.Hylete.com Weight Loss | How Fat Burning Works | Lipolysis Explained– Thomas DeLauer… So you want to burn fat - what exactly does that mean? In order to burn fat most efficiently, it is important to first understand how fat metabolism works. Fat must be released from our cells. Only once the fat has been released can it be burned and used for energy. The majority of fat in our bodies resides in fat cells. These cells are made up of roughly 15% lean mass and 85% fat, in the form of a lipid droplet. To use this fat we must get it to cross over the cell membrane of the fat cell. This process is called lipolysis. An enzyme called hormone-sensitive lipase takes a triglyceride, the fat in the cell, and separates the three fatty acids from the glycerol. This frees the fatty acids to pass through the cell membrane to be made available to the Krebs Cycle. So to use your stored fats as fuel, you need to produce hormone-sensitive lipase. Many hormones are involved here, but the one that you want to be most concerned with is insulin. If you have high levels of insulin in your blood, you are going to have low levels of lipase. Dietary carbohydrates are the main contributor to your blood insulin levels. So how do we burn our stored fat? The Krebs Cycle: You may remember from biology class the Citric Acid Cycle, also known as the Krebs cycle. Mitochondria are found in the hundreds to thousands in all cells in our body (except mature red blood cells). Here, energy from what we eat, the carbohydrates, fats and proteins, are converted into ATP. Acetyl COA is used to form the energy, or ATP, in the Krebs cycle: If you are consuming carbohydrates or eating too frequently, your blood is going to have high insulin levels and there will be carbohydrates that you have recently eaten available as the fuel for the Krebs Cycle. Traditionally, carbohydrates that you eat are broken down in your body. The glucose undergoes a process called glycolysis and pyruvate is formed. In the mitochondrial matrix, pyruvate undergoes oxidation and ACOA is formed. ACOA can also be formed from the breakdown of fats and amino acids, or the building blocks of proteins. How your body uses its energy is dependent upon what you eat. Traditionally, when you are in a normal state, your body is using carbohydrates for their main energy source through the citric acid cycle. If you change how you eat, you can train your body to instead form ACOA through the breakdown of ketone bodies. How Does it Work? When glucose is in short supply, your body begins lipolysis. These free fatty acids, rather than carbohydrates from your food, are used to produce ACOA. Once the fatty acids have been released into your bloodstream, they bind to a protein called albumin. Albumin shuttles the fatty acids to the muscle cells where they are taken into the mitochondria as ACOA. In very fit athletes the muscle cells themselves will begin to store the lipid droplets in them rather than glucose for immediate energy fuel. Lipogenesis: When you eat carbohydrates, they break down into glucose in your blood. The pancreas secretes insulin to shuttle the glucose out of the blood and into either the muscle or liver for immediate use, glycogen storage, or they be stored as fat. Your liver and muscle cells have a limited capacity for glycogen storage that is not very high. This means that when you consume excess carbs your body has to store them as fat through a process called lipogenesis. Simply put, lipogenesis is the creation of fatty acids from carbohydrates that you consume. While for our ancestors in the hunting and gathering days this storage of energy was great, in the age of abundance we are struggling with the health impacts of storing excess fat. This fat storage follows a process very similar to the Krebs Cycle discussed. Once the ACOA is created, if the body does not need to use it for energy or for storage in the muscles and liver, it is stored through lipogenesis as fat for later use. References: 1. The Citric Acid Cycle https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle 2. The citric acid cycle oxidized two-carbon units http://www.ncbi.nlm.nih.gov/books/NBK22427/ 3. What is Ketosis? Our article :) 4. Fat Breakdown and Fat Burning: Lipolysis and Oxidation http://leanmessengers.com/fat-breakdown-and-fat-burning-lipolysis-and-oxidation/ 5. How and what am I digesting? A breakdown of macronutrient… http://leanmessengers.com/?s=lipogenesis 6. Lipid catabolism summary http://chemistry.elmhurst.edu/vchembook/622overview.html 7. Acetyl COA - Crossroads Compound http://chemistry.elmhurst.edu/vchembook/623acetylCoAfate.html

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