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👇 Visit The Proof website for the full show notes and supporting studies. 👇 https://theproof.com/podcast/ You’ve probably heard the claim: "If you’re lean and metabolically healthy, high LDL doesn’t matter." In low-carb circles, it’s more than a claim, it’s a permission slip to eat as much butter and bacon as you like. But is that confidence backed by science? In this solo episode, I break down the much-discussed KETO-CTA study that aimed to assess cardiovascular risk in lean individuals following a long-term ketogenic diet. With commentary from Dr. Alan Flanagan, who co-authored a formal critique of the study, we examine the actual data and how it was presented. Whether you follow keto, are concerned about your LDL, or just want clarity on cardiovascular risk, this episode cuts through the noise. What we cover: - Who are Lean Mass Hyper-Responders (LMHRs) and why they were studied - What the KETO-CTA study actually measured and why calling it a "trial" is misleading - The significance of Non-Calcified Plaque Volume (NCPV) and Percent Atheroma Volume (PAV) - Why the primary outcome data was omitted from the published paper and why that matters - ApoB levels and plaque progression: what the study showed and what it didn't - The role of exploratory vs. pre-registered outcomes in research - Problems with media coverage and misleading headlines - How this study compares to others using similar imaging methods - Why the average subject showed plaque growth 4x faster than expected - What this means for people on a ketogenic diet with elevated ApoB - The importance of responsible science communication Subscribe and stay connected: Found this episode valuable? Subscribe to The Proof on YouTube and hit the notification bell to stay updated. Listening on Spotify or Apple Podcasts? Follow the show to ensure you never miss an episode. Support the show: The best way to support the show is to use the products and services offered by our sponsors. Visit http://theproof.com/friends for exclusive discounts. If you have any additional questions you would like answered in the future, let me know in the comments. Enjoy, friends. Simon This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to https://38tera.com/?ref=SIMON and use code PROOF for 25% off at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at https://www.bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on http://im8health.com/ Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at http://eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase at http://drinklmnt.com/simon Find your favorite LMNT flavor, or share with a friend. And if you don’t like it? Full refund, no questions asked. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on http://join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) - Creator of http://theproof.com/ - Host of https://theproof.com/podcast/ - Author of https://theproof.com/book/ Subscribe & Connect: - YouTube: https://www.youtube.com/c/TheProofWithSimonHill?sub_confirmation=1 - Apple Podcasts: https://podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 - Spotify: https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b - Instagram: https://www.instagram.com/theproof/ - X: https://x.com/theproof - Facebook: https://facebook.com/theproofwithsimonhill - Nourish your gut with my https://theproof.com/ferments/ and download my https://theproof.com/mealplan.

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http://why-am-i-fat.info/ Why am I still fat? I diet, I exercise, I don't eat any worse than anyone else I know yet I just can't seem to lose weight. Click through the link above and find out a few facts about why you always feel tired and CAN'T LOSE THAT BULGE!

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Looking for a quick and effective way to reduce belly fat and sculpt your waist? 💃 Try these powerful at-home exercises that target the belly, waistline, and lower body. ✅ Perfect for beginners & women ✅ No equipment required ✅ Results in as little as 14 days ✅ Do 3 sets of 15–20 repetitions for each exercise 👉 Stay consistent, eat well, and watch your waistline shrink! Try this routine and say hello to a toned belly and strong legs! 💪👙 #bellyfatworkout #waistworkout #homeworkout #womenworkout #bellyfatloss #waistlineworkout #legworkout #noequipmentworkout #fitnessmotivation #fitwomen #dailyworkout #7daychallenge #bellyfatburn #quickworkout #athomeworkout #weightlossworkout #tonebelly #legtoning #beginnersworkout #fitnesstips

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In adults with a BMI ≥30, daily subcutaneous semaglutide proved more effective than liraglutide and placebo in promoting weight loss. ⚠️ Note: Gastrointestinal symptoms were the primary side effect, highlighting the importance of patient counseling. 💡 Takeaway: Semaglutide is a powerful tool for weight management in patients with obesity, offering a significant advantage over other therapies. #ObesityManagement #WeightLoss #Semaglutide #Liraglutide #BMI #GLP1RA #DiabetesCare #Endocrinology #MedicalResearch #Pharmacology #ClinicalTrials #LifestyleMedicine #ObesityTreatment #short

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HAPPY NEW YEAR!!!! Start your year off by tuning in to the NEW EPISODE of Kickback Science: "Behind the Curtain: The Real Deal With GLP-1 Agonists". https://bit.ly/40fWMxC Here is a clip where we are discussing some issues with the clinical trials that were done on the popular new GLP-1 weight-loss injections. These medications have shown to be incredibly effective at helping people lose weight. The weight-loss is believed to be due to GLP-1's ability to activate satiety signaling (making people feel fuller), reducing reward-driven signals that trigger overeating, and slowing down digestion.. Yaaaaayyyy finally something to help stop my non-stop craving of chocolate chip cookie dough ice cream!!! Diet is the most difficult part of the weight-loss journey, and now we have a tool to make it easy?!!! You're probably thinking that these medications sound too good to be true. And you might be right. You see, these clinical trials do a great job showing weight loss with these medications, but they fail to reports WHAT KIND OF WEIGHT the participants are losing (is it fat or muscle?). And that's because the FDA only requires pharmaceutical companies to report weight loss, as opposed to body composition changes. This is SUCH a bummer! Fortunately, a small subset of participants in the STEP1 clinical trial (PMID: 33567185) underwent body composition testing (included in the supplemental files of the publication), which showed that they were losing almost as much muscle as fat. THIS IS NOT HEALTHY! If you haven't yet, tune in to the Kickback Science episode titled: "MUSCLE MANIA! Why Muscle is The Most Important Organ in Your Body". Then you'll understand what I mean when I say that there is reason to be concerned about the loss of muscle with these medications. https://bit.ly/3VXv9a8 #health #fitness #muscle #strength #diet #nutrition #weights #healthylifestyle #science #research #podcast #kickbackscience #exercise #sleep #medicine #GLP1 #weightloss #ozempic #wegovy #zepbound #mounjaro

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📢 “GLP-1 is just the easy way out!” If you’ve ever heard this, you’re not alone. But is it true? Does taking GLP-1 medication mean you’re not ‘really’ losing weight? Or is this just outdated diet culture nonsense? 🚨 In today’s video, we’re breaking down: ✔️ Why GLP-1 is more than just appetite suppression 🧬 ✔️ The SCIENCE behind why weight loss isn’t just about willpower 🔬 ✔️ The HARD WORK that still has to happen on GLP-1 💪 ✔️ Why using medication for weight loss isn’t ‘cheating’—it’s smart 🎯 💬 What do you think? Do you believe GLP-1 is the ‘easy way out’? Drop a comment below—I want to hear your take! 🔔 Subscribe for More: I drop weekly videos on weight loss, GLP-1, and real-life strategies that WORK. #GLP1 #WeightLoss #WeightLossJourney #Metabolism #Ozempic #Mounjaro #Zepbound

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In this video, I share my personal story of how my insurance company forced me to switch from Zepbound to Wegovy, even though both are GLP-1 weight loss medications Zepbound has proven to work for me and my body. Their mandate isn’t about what’s best for patients or individual health needs — it’s about insurance companies pushing their own agendas and controlling which weight loss meds we can access. Many people are facing these sudden forced switches from tirzepatide (Zepbound) to semaglutide (Wegovy), not because of safety or effectiveness, but because insurance wants to cut costs and maximize profits. If you’re on a GLP-1 medication for weight loss, this affects you too. We need to talk about how insurance companies dictate our health decisions, prioritize profits over patient care, and create anxiety for those who rely on these medications to manage obesity and improve metabolic health. Chapters: 0:00 Introduction 0:22 Insurance Forcing the Move 1:10 The Concern 1:24 Difference Between the 2 2:14 Comparison Article 2:58 What You Can Do 10:15 Outro SOURCES: 1. https://www.breakthrurx.com/semaglutide-tirzepatide 2. https://www.cnbc.com/2024/12/19/fda-eli-lilly-weight-loss-drug-zepbound-no-longer-in-shortage.html?utm_source=chatgpt.com 3. https://pmc.ncbi.nlm.nih.gov/articles/PMC11153294/?utm_source=chatgpt.com#sec3 4. https://lillydirect.lilly.com/pharmacy/zepbound 5. https://investor.lilly.com/news-releases/news-release-details/lillys-zepboundr-tirzepatide-superior-wegovyr-semaglutide-head?utm_source=chatgpt.com 💌📨CONTACT INFO: EMAIL: [email protected] ➡️ DON'T FORGET TO 👍, COMMENT, SHARE, AND SUBSCRIBE TO MY CHANNEL. HIT THAT NOTIFICATION 🔔SO YOU WILL BE NOTIFIED WHEN THE NEXT VIDEO DROPS. ❤️ RELATED SEARCH = ZEPBOUND TO WEGOVY, ZEPOUND VS. WEGOVY, ZEPBOUND, BEFORE AND AFTER, OZEMPIC, MOUNJARO, WEGOVY, GLP-1, ZEPBOUND RESULTS, ZEPBOUND INJECTIONS, TIRZEPATIDE, DIETING, WEIGHT LOSS, RAPID WEIGHT LOSS, FAST WEIGHT LOSS, SEMAGLUTIDE, ZEPBOUND HACKS #lifeaccordingtoself #insurance #weightloss #weightlossjourney #weight #diet #dietfood #ozempic #ozempicweightloss #mounjaro #wegovyweightloss #wegovy #zepbound #glp #glp1forweightloss #semaglutide #tirzepatide #mounjaro #mounjaroweightloss #ozempicjourney #dieting #losingweight #howilostweight #zepboundstory #howtousezepbound #weightlossmotivation

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