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Presented by Kelly Heim, PhD+ Originally Aired: October 2024 Description: GLP-1 agonists are widely used for metabolic and weight loss applications, with an estimated 12% of U.S. adults reporting current or past use.1 Common adverse effects often limit the overall success of GLP-1 therapies. This lecture reviews the basic and clinical pharmacology of GLP-1 agonists, with a special focus on nutritional strategies for managing common adverse effects and supporting durable weight management after drug discontinuation. Learning Objectives: • Review the functions, indication and mechanism of action of GLP-1 agonists • Recognize common adverse effects of GLP-1 agonists • Discover nutritional and lifestyle interventions to help manage occasional gastrointestinal adverse effects and preserve lean body mass • Learn how to prevent weight rebound after drug cessation About the speaker: Kelly C. Heim, PhD, is a Senior Consultant of Medical Affairs at Pure Encapsulations® and Founder and Senior Science Editor at Integrative Pharmacology. He received his doctoral degree in pharmacology from Geisel School of Medicine at Dartmouth College and specializes in the pharmacology of natural compounds. Dr. Heim is a published author and illustrator of various studies, scholarly reviews and book chapters. He offers complimentary learning resources on the basics of clinical pharmacology of natural products via his website, IntegrativePharmacology.com. +Dr. Heim is an employee of Pure Encapsulations. 1. Harris E. Poll: Roughly 12% of US Adults Have Used a GLP-1 Drug, Even If Unaffordable. JAMA.2024;332(1):8. doi:10.1001/jama.2024.10333

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Apple cider vinegar (ACV) has been gaining popularity in recent years for its various health benefits, particularly for weight loss. Recently, a new product called Simply Health ACV Keto appeared on Shark Tank, a popular television show where entrepreneurs pitch their products to a panel of investors. In this episode breakdown, we will discuss the details of the pitch, the reactions of the sharks, and whether Simply Health ACV Keto was able to secure a deal.

Product Pitch

The founders of Simply Health ACV Keto entered the Shark Tank with confidence, touting their product as a revolutionary weight loss supplement that combines the benefits of apple cider vinegar and the ketogenic diet. They claimed that by taking their product, users could experience rapid weight loss, increased energy, and improved overall health.

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According to the founders, Simply Health ACV Keto is made with all-natural ingredients and is free of any harmful chemicals or additives. They emphasized that their product was backed by scientific research and had already received positive reviews from satisfied customers.

To demonstrate the effectiveness of their product, the founders shared impressive before and after photos of individuals who had used Simply Health ACV Keto and achieved significant weight loss results. They also presented data on the growing market for health and wellness products, highlighting the potential for strong sales and customer retention.

Shark Reactions

Initially, the sharks seemed intrigued by the potential of Simply Health ACV Keto and praised the founders for their innovative approach to weight loss. However, as the pitch progressed, some of the sharks raised concerns about the lack of clinical evidence supporting the effectiveness of the product.

Mark Cuban questioned the founders about the safety and regulatory compliance of Simply Health ACV Keto, while Lori Greiner expressed skepticism about the long-term sustainability of the business. Kevin O’Leary, known for his tough negotiation tactics, grilled the founders on their sales projections and manufacturing processes.

In the end, the sharks were divided in their opinions on Simply Health ACV Keto. While some saw the potential for growth and profitability, others were hesitant to invest without more concrete evidence of the product’s efficacy.

Deal or No Deal?

After much deliberation, the founders of Simply Health ACV Keto ultimately left the Shark Tank without a deal. While they received some interest from the sharks, none were willing to commit to an investment without further validation of the product’s claims.

Despite the setback, the founders remained optimistic about the future of Simply Health ACV Keto and pledged to continue working on improving their product and expanding their customer base. They thanked the sharks for their feedback and vowed to return stronger than ever.

In conclusion, the episode featuring Simply Health ACV Keto on Shark Tank was a rollercoaster of emotions for both the founders and the sharks. While the product showed promise, it ultimately failed to secure a deal due to concerns over its efficacy and long-term viability. Only time will tell if Simply Health ACV Keto can overcome these obstacles and become a successful player in the competitive health and wellness industry.