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BMO Capital Markets managing director of biopharma equity research Evan Seigerman joins Market Domination to discuss the best biotech plays outside of the GLP-1 weight-loss space. The sky-high demand for GLP-1 weight-loss drugs has led the biotech sector to reach new heights over the last year, and Seigerman believes the trend is as "hot as ever." He notes that the 2024 European Association for the Study of Diabetes (EASD) meeting revealed key data highlighting the importance of these weight-loss drugs, and he believes that players like Eli Lilly (LLY) and Novo Nordisk (NVO) continue to lead the industry's growth. However, he sees opportunities outside of the GLP-1 landscape, pointing specifically to Regeneron (REGN) and Vertex (VRTX) as prime examples. Vertex, a leader in cystic fibrosis research, makes up about $10 billion of its core franchise. The company is on track for early 2025 approval of its next-generation cystic fibrosis treatment as well as a non-opioid, non-addictive pain medication. In addition, Vertex has partnered with CRISPR Therapeutics (CRSP) and received approval for Casgevy, a cell therapy treatment for sickle cell disease and beta-thalassemia. Seigerman notes that the uptake has been slow as it requires patients to be in the hospital for at least a month as they go through the process. However, he explains that the therapy works and is "really transformational" for patients. While Seigerman is bullish on Vertex, he notes that the stock's price is rather high, trading in the upper $400s. The other risk he highlights is a non-opioid paid medication competitor coming to market. #youtube #stockmarket #news About Yahoo Finance: Yahoo Finance provides free stock ticker data, up-to-date news, portfolio management resources, comprehensive market data, advanced tools, and more information to help you manage your financial life. - Get the latest news and data at finance.yahoo.com - Download the Yahoo Finance app on Apple (https://apple.co/3Rten0R) or Android (https://bit.ly/3t8UnXO) - Follow Yahoo Finance on social: X: http://twitter.com/YahooFinance Instagram: https://www.instagram.com/yahoofinance/?hl=en TikTok: https://www.tiktok.com/@yahoofinance?lang=en Facebook: https://www.facebook.com/yahoofinance/ LinkedIn: https://www.linkedin.com/company/yahoo-finance

His Is Usalum Chrissy Metz Recalls Prefame Weight Discrimination On Airplanes Passengers

The World Health Organization is set to officially endorse weight-loss drugs to treat obesity in adults! 🌍💊 This marks a major shift in global health policy. In this video, we break down what it means, how these medications work, their pros and cons, and the impact this could have worldwide. Don’t miss this important health update! 🚨📉 Tags: #WeightLossDrugs #WHOUpdate #ObesityTreatment #HealthNews #Ozempic #Wegovy #Mounjaro #GlobalHealth #GLP1 #MedicalBreakthrough

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Working out and still struggling to lose fat? Watch this video. Total Fitness Bodybuilding Inner Circle: http://www.TotalFitnessBodybuilding.com Follow my Blog: http://www.leehayward.com Facebook: http://www.facebook.com/total.fitness.bodybuilding Twitter: https://twitter.com/leehayward Losing bodyfat can be a real challenge for some people. Your genetic body type has a lot to do with this, because some people can just eat and eat and never seem to gain a pound. And other seem to gain weight even if they are physically trying to lose weight. That's the case we're going to cover here in this video. Just the other day I got this question from one of my subscribers: Scott wrote... "Lee, I follow most of ur workouts from youtube my diet is really strict I have my cheat day and that is it I work out six days a week and before I workout I do 15-20 minutes of cardio I ride a bike 20-30 miles a day and work out for about 45-60 minuters using a cardio-style weight lifting... I follow your youtube for my mass days and use supplements for the protein I do not get.... I use amino's halfway thru my workout as u suggest and still gain weight fat not muscle it is aggervating." In Scott's case he is doing A LOT of exercise with weight training, cardio in the gym, plus riding his bicycle. So lack of exercise is not his problem. Based on the info he provided my guess is that he is simply eating too much. Now granted he did say he was very strict with his diet, but strict doesn't always mean "low calorie". Even if you are eating very clean, healthy food, you can still eat too much to lose fat. Whether or not you gain weight or lose weight comes down to calories in verses calories out. And all that exercise will create a big appetite, so if you are not careful it's still possible to overeat and not be in a caloric deficit, despite all the exercise. A good general rule of thumb to follow for fat loss is to consume 12 calories per pound of bodyweight per day. This will be low enough for most people to be in a caloric deficit and allow them to burn stored bodyfat for fuel. So if you are doing A LOT of exercise (like Scott is) and still not losing weight. Take a closer look at your diet and actually calculate how many calories you are eating on a daily basis. If you are eating more than 12 calories per pound of bodyweight per day, then this could be the reason you are not losing weight. Rare Exceptions To The Rule... While these calorie calculations will work for most people, there will always be exceptions to the rule. So if you are following a very low calorie diet (i.e. 12 calories per pound of bodyweight or less) and still not losing weight. Than you may be actually eating too low of a caloric intake and unknowingly slowing down your metabolism. When you don't eat enough calories, coupled with high volume exercise, your body can go into "survival mode" and actually shut down it's metabolic processes in order to conserve calories and cling onto stored bodyfat. This is the exact opposite of what you want to achieve. If this is the case, then you need to incorporate a form of calorie cycling diet plan in order to help re-set the body's natural metabolic rate. This is where you'll purposely go through phases of consuming a caloric surplus, a caloric maintenance, and a caloric deficit in order to allow your body to burn fat, while keeping your metabolic rate high. If you need help with setting up this style of calorie cycle diet plan, you should visit my website to learn more about my Customized Diet & Training Programs at: http://www.leehayward.com/blog/customized-programs

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