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Hey everyone, Connor with Honor here! In this portion of the video, I dive into losing body weight with FDA-approved meds—specifically GLP-1 agonists like Ozempic, Wegovy, and more. As someone who once weighed 365 lbs with a 65-inch waist, I understand the daily battles with diet, cravings, and health issues. Over the course of 7.5 months, I managed to drop 135 lbs of fat through a combination of fasting, hormone therapy, and a whole lot of discipline. But even with that success, I’m always looking for new insights on weight loss—especially the pros, cons, and potential pitfalls of modern medications. In this segment (roughly 00:04:24 – 00:11:23), I discuss how drugs like Ozempic and Wegovy can suppress appetite, helping you reduce your overall caloric intake in a way that mimics some benefits of fasting. However, there’s a major caveat: muscle loss. If you’re not pairing these meds with resistance training, you risk losing lean body mass that’s already tough to build (or rebuild). And that’s why I’m sounding the alarm—because losing fat is great, but losing muscle can ultimately hurt your metabolism, bone density, and overall strength. Below, you’ll find more highlights from this section of the video, along with direct links to my full YouTube upload and an in-depth blog post detailing everything I’ve learned on this topic. Read on for the breakdown: 1. My Personal Journey (00:04:24 – 00:05:40) I spent much of my life overweight—even while I was serving as a police officer for the LAPD. After countless yo-yo diets, I discovered fasting (ranging from a day to 14 days straight) and hormone therapy to address low testosterone levels. This combination helped me go from 365 lbs to around 230 lbs in about 7.5 months, torching 135 lbs of fat. Why This Matters: If you’re considering FDA-approved weight loss meds, ask yourself if it’s riskier to remain obese or to try a doctor-supervised medication. It’s not a simple yes/no question—your personal health context matters, and you’ll want professional guidance either way. 2. GLP-1 Agonists: Appetite Suppression & Cautions (00:05:41 – 00:09:00) Ozempic, Wegovy, and similar meds are known as GLP-1 receptor agonists, which can drastically reduce your hunger signals. Think of it like a “chemical version” of intermittent fasting. Muscle Loss Concerns: Because these drugs curb your appetite, you might eat too few calories, prompting your body to target lean tissue (i.e., your muscles) for energy. Over time, this can lower your metabolism. What Science Says: Some studies suggest a significant portion of the weight lost on GLP-1 meds can be muscle unless you adopt resistance training to preserve strength. 3. Fasting vs. Meds: Metabolic Myths (00:09:01 – 00:10:10) Fasting can actually increase your metabolism by around 10% (especially in the early stages), contrary to the old “fasting = starving” myth. It’s your body’s evolutionary response to get you energized enough to hunt. With GLP-1 meds, you’re still eating (just far less), so you might not get the same metabolic bump from fasting. Instead, it’s more like a “chronic calorie restriction,” which might lower your metabolic rate if not done correctly. Remember: Metabolism is about more than just calories in vs. calories out. Hormones, muscle mass, and daily activity levels all play vital roles. 4. Doctor Visits & Hard Questions (00:10:11 – 00:11:23) I once asked a skeptical doctor, “What’s riskier for me: remaining at 365 lbs or taking a medically supervised hormone replacement?” The doctor couldn’t give a solid answer. If you’re considering GLP-1s (or any weight-loss med), ask yourself: Is the bigger risk staying at my current weight or trying this prescription? Every choice has trade-offs. Side Effects & Long-Term Unknowns: GLP-1 meds are relatively new in the mainstream market. Keep an eye on side effects and stay in close contact with your healthcare provider. Watch the Full Video YouTube Link (raw): https://youtu.be/2TEsk6oNrdE?si=n9cyr9r_RCAqS9J2 Time Range: This weight-loss segment starts around 00:04:24 and runs to about 00:11:23. If you want to see my entire discussion—from Santa Clarita real estate updates to AI concerns and a pep talk for young men stuck in basements—watch the video in full. Everything’s timestamped, so you can jump right to the parts that interest you. Read the Detailed Blog Post If you’re craving more context—like how these topics tie into real estate, tech shifts, or general self-improvement—check out my blog post for a comprehensive rundown of all four segments covered in this video: Blog Link (raw): https://www.santaclaritaopenhouses.com/2025-santa-clarita-update-glp-1-agonists-fat-ai-dangers-boys-to-men —Connor with Honor Former LAPD, current Santa Clarita Realtor, and an ever-learning human on a mission to help others live healthier, smarter, and more fulfilling lives.

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In this episode, Dr. Gandolfo addresses a compelling question from a listener who is curious about the use of GLP-1 drugs, such as Ozempic and Mounjaro, in patients with inflammatory bowel diseases like Crohn's and ulcerative colitis. Dr. Gandolfo provides a comprehensive overview of GLP-1 drugs, explaining how they function as agonists to stimulate insulin secretion and promote weight loss by altering gut motility and suppressing appetite. Delving into the potential implications for patients with inflammatory bowel disease, Dr. Gandolfo explores recent studies suggesting that GLP-1 drugs might be well-tolerated and could even offer benefits in reducing bowel frequency for patients who have undergone colectomy. While these findings are promising, he emphasizes the need for further human studies to confirm these effects. Dr. Gandolfo also addresses common side effects associated with GLP-1 drugs, such as nausea, and reassures listeners about the overall safety of these medications. He highlights the importance of discussing individual risks and benefits with a healthcare provider before starting any new treatment. Referenced in this episode: DDW abstract on safety of GLP-1 drugs with IBD (https://ddw.digitellinc.com/p/s/safety-and-clinical-effectiveness-of-glp1-agonists-in-inflammatory-bowel-disease-patients-6648) Study of GLP-1 drugs and risk of IBD flare (https://pubmed.ncbi.nlm.nih.gov/39438251/) GLP-1 drugs and possible mechanism of benefit in IBD patients (https://pubmed.ncbi.nlm.nih.gov/37081371/) Pilot study using GLP-1 agonist to reduce diarrhea in colectomy patients (https://pubmed.ncbi.nlm.nih.gov/38668926/) Review of mechanism of action of GLP-1 (https://pubmed.ncbi.nlm.nih.gov/29617641/) Be sure to subscribe to The Real GI Doc Show for more insights, and reach out with your questions on social media @realgidoc or leave an audio question for Dr. Gandolfo here (https://www.realgidoc.com/p/submit-a-question/) . Find The Real GI Doc Show on social media, join the newsletter, read Dr. Gandolfo's bio, or ask a question using this link. (https://realgidoc.start.page/) Watch this episode on The Real GI Doc Show YouTube channel! (https://www.youtube.com/@realgidoc)

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Are you looking to achieve your weight loss goals and improve your overall health and wellbeing? Pure BHB Keto is a revolutionary supplement that has taken the diet world by storm, thanks to its powerful ketogenic formula. With its appearance on Shark Tank, Pure BHB Keto has garnered even more attention for its effectiveness and purity. In this article, we will delve into the world of Pure BHB Keto on Shark Tank and explore the purity of ketosis.

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Ketosis is a natural metabolic state in which your body burns fat for fuel instead of carbohydrates. By following a ketogenic diet or using a supplement like Pure BHB Keto, you can easily achieve ketosis and experience a wide range of benefits. These benefits include rapid weight loss, increased energy levels, improved mental clarity, and enhanced physical performance.

Pure BHB Keto contains exogenous ketones, specifically Beta-Hydroxybutyrate (BHB), which helps to kickstart ketosis in your body. BHB is a powerful ketone that can cross the blood-brain barrier and provide your brain with a clean and efficient source of energy. This can help improve cognitive function and mental focus while also reducing cravings and appetite.

By entering ketosis, your body switches from burning glucose to burning fat for fuel. This can lead to rapid weight loss, especially in stubborn areas like belly fat. Additionally, ketosis can help regulate blood sugar levels, reduce inflammation, and protect against chronic diseases such as diabetes and heart disease.

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When it comes to choosing a ketosis supplement, purity is key. Pure BHB Keto is made with all-natural ingredients and is free from artificial additives, preservatives, and fillers. This ensures that you are getting a pure and safe product that can help you achieve your weight loss goals without any harmful side effects.

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