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Fuck cardio. If your only goal is to lose weight and your first move is cardio... you're doing it wrong. Sure, you'll drop weight — but it's fat and muscle. And when you gain it back (because cardio alone isn’t sustainable), it comes back as pure fat. Want to look lean, strong, and actually keep the weight off? 👉 Lift weights. Build muscle. Muscle = higher metabolism = more calories burned at rest = long-term results. Stop chasing quick fixes. Start building a body that lasts
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In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes. The conversation explores how GLP-1 receptor agonists, have evolved into powerful medications. These drugs help patients achieve significant weight loss, reverse diabetes, improve cardiovascular health, reduce inflammation, and potentially enhance cognitive function. Dr. Holst delves into their long-term implications for preventing diabetes, extending health spans, and even reducing the risks of obesity-related cancers and improving fertility. Dr. Holst emphasizes that while GLP-1 offers life-changing benefits, sustainable health still hinges on balanced diets and regular physical activity. This episode provides a fascinating look at the intersection of science, medicine, and lifestyle in promoting longevity. Sign up for updates about each new episode: https://info.insidetracker.com/longevitybydesign View show notes here: https://blog.insidetracker.com/longevity-by-design-podcast-jens-juul-holst Episode highlights: Introduction: 00:00:00 What is GLP-1: 00:03:00 what is a GLP-1 agonist: 00:04:15 what are the target organs of the GLP-1 agonist?: 00:06:30 what is the effect of the GLP-1 agonist on a diabetic patient? : 00:10:00 What percentage of a diabetic patient on GLP-1 have complete remission: 00:11:30 How long did it take to bring a drug to market from the moment you first discovered it: 00:23:30 What is the GLP-1 effect on cognition and dementia: 00:29:00 GLP-1 effect on kidney diseases: 00:32:00 GLP-1 positive effect on fertility: 00:35:00 GLP-1 positive effect on cancer: 00:37:30 Should a patient be on GLP-1 for life: 00:41:00 GLP-1 related side effects: 00:48:00 GLP-1 effect on resting heart rate: 00:52:30 GLP-1 related side effects: 00:48:00 GLP-1 from Lilly vs novo nordisk: 00:55:00 GLP-1 oral versus the injectable: 00:58:00 GLP-1 effect on lifespan: 01:00:30 GLP-1 effect on lifespan: 01:00:30 What led you to become a scientist: 01:03:00 The story of discovering the GLP-1: 01:04:30 How did you successfully extend the half-life of the GLP-1 agonist: 01:09:00 GLP-1 moving from once a day to once a week: 01:16:00 Top tip to improve healthspan: 01:18:00 GLP-1 Agonists: A Game-Changer for Diabetes and Obesity Dr. Jens Juul Holst explores the revolutionary impact of GLP-1 agonists in treating diabetes and obesity. These medications mimic a natural gut hormone to regulate insulin secretion, appetite, and weight. Through their ability to normalize blood glucose levels and promote significant weight loss, GLP-1 agonists have transformed the lives of patients with type 2 diabetes and obesity. Holst highlights their success in enabling over 50% of diabetes patients to achieve normal glucose levels while addressing the systemic health risks tied to obesity. This innovation represents a monumental leap in metabolic disease management. Beyond Weight Loss: Cardiovascular and Inflammatory Benefits of GLP-1 Dr. Holst emphasizes the additional health advantages of GLP-1 agonists, beyond their effects on diabetes and obesity. These drugs improve cardiovascular outcomes by reducing major adverse events such as heart attacks and strokes. They also decrease systemic inflammation, a common issue in metabolic diseases. Holst points out that GLP-1 therapy’s dual action on vascular health and inflammation positions it as a comprehensive solution for improving long-term health outcomes in patients with diabetes or obesity. The Impact of GLP-1 on Fertility Dr. Holst explores GLP-1’s surprising potential in fertility treatments, particularly for individuals with metabolic-related infertility issues, such as polycystic ovary syndrome (PCOS). He explains that improving metabolism and reducing insulin resistance with GLP-1 therapy can enhance fertility outcomes for both men and women. Although he urges caution due to limited long-term data, Holst notes the promising effects observed in clinical experiences. “If you can ameliorate the metabolism of these individuals, they will immediately become pregnant. And we knew that already. You can even do it with metformin…Once GLP-1s were introduced, it turned out that yes, these people became pregnant.” We Appreciate You! As a token of our gratitude, we’re excited to offer you 15% off your next purchase. Simply click the link below to redeem your discount: https://info.insidetracker.com/podcast For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast
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Can Keto Lower My Blood Pressure And Affect My Medication? In this informative video, we’ll discuss the ketogenic diet and its effects on blood pressure, particularly for those taking antihypertensive medications. The ketogenic diet, known for its low carbohydrate and high fat intake, has gained popularity for its potential health benefits. We will explore how this dietary approach may influence blood pressure levels, especially in individuals dealing with excess weight or metabolic challenges. We will also cover the relationship between the ketogenic diet and blood pressure medications, highlighting the importance of monitoring your blood pressure closely if you decide to adopt this eating style. It’s vital to consult with your healthcare provider to ensure that any necessary adjustments to your medication are made to maintain safe blood pressure levels. Additionally, we’ll touch upon the quality of fats and proteins consumed on a ketogenic diet, which can greatly impact overall heart health. Join us for this essential discussion and subscribe to our channel for more helpful tips and information on the ketogenic lifestyle and its effects on health. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@KetoKitchenHQ/?sub_confirmation=1 #KetoDiet #BloodPressure #Hypertension #Antihypertensive #HealthTips #WeightLoss #DietaryChanges #Nutrition #HeartHealth #KetoLifestyle #HealthyEating #MedicationManagement #LowCarb #FatLoss #WellnessJourney #HealthyLiving About Us: Welcome to Keto Kitchen HQ, your go-to channel for everything related to the keto diet. Whether you're a beginner looking to understand Keto Diet Basics or an experienced practitioner refining your approach, we cover a range of topics including Low-Carb Meal Planning, Ketosis Explained, and Keto-Friendly Foods. Our engaging videos will help guide you on your journey with insights into Intermittent Fasting, Keto for Weight Loss, and delicious Ketogenic Recipes.
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Nova Optimal Keto Gummies are packed with essential nutrients, including BHB (Beta-Hydroxybutyrate) ketones, that can help your body reach ketosis faster and more effectively. Ketosis is the state in which your body burns fat for energy instead of carbs, leading to weight loss and increased energy levels. By supplementing your keto diet with these gummies, you can experience these benefits quicker and easier than ever before.
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Q: How long will it take to see results with Nova Optimal Keto Gummies?
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The trend of GLP 1 drugs has certainly been an interesting one this year. I first heard about this almost a year ago and have been surprised at how quickly these have taken hold as an observer Disclaimer: Investing has risk of loss of some or complete loss of principle. This post if for entertainment and not advice. If you are not a client of Parkmount, we disclaim any responsibility for actions taken as a result of this post. Please consult an advisor before taking any actions. Views expressed here are believed to be accurate but are subject to change and may contain errors.
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