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00:00 - Intro 00:12 - UK Investigates Fatal Pancreatitis Linked to Weight-Loss Drugs 03:12 - Hidden Eye Risks of GLP-1 Weight Loss Drugs: What You Need to Know 1. UK Investigates Fatal Pancreatitis Linked to Weight-Loss Drugs The UK's Medicines and Healthcare products Regulatory Agency (MHRA) has launched an investigation into potentially fatal pancreatitis cases linked to GLP-1 weight-loss drugs like Ozempic and Wegovy. Their Yellow Card scheme received nearly 400 reports of serious pancreas issues, including at least 10 deaths. Acute pancreatitis causes severe abdominal pain, nausea, and fever, often requiring hospitalization. Although drug pamphlets list this as an uncommon side effect (1 in 100 users), the severity has prompted genetic risk analysis. Pharmaceutical companies Novo Nordisk and Lilly emphasize strict medical supervision but maintain positive benefit-risk profiles. US regulators haven't opened formal investigations but mandate pancreatitis warnings on all GLP-1 drugs. Studies show users face twice the risk of pancreatitis compared to non-users. 2. Hidden Eye Risks of GLP-1 Weight Loss Drugs: What You Need to Know GLP-1 receptor agonists (GLP-1 RAs) like Ozempic and Wegovy are popular for weight loss and diabetes management. While effective, recent studies suggest potential risks to eye health, including optic neuropathy and worsening diabetic retinopathy. This video explores the latest research, mechanisms behind these risks, and what patients and doctors should watch for. Learn about the benefits and drawbacks of GLP-1 RAs, who might be at higher risk, and why regular eye exams are crucial for those on these medications. Stay informed to make the best decisions for your health. #GLP1 #WeightLossDrugs #EyeHealth #DiabeticRetinopathy #OpticNeuropathy
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🚨 New Breakthrough in Type 2 Diabetes Care! 💊🧬 The ACHIEVE-1 trial shows that Orforglipron, a once-daily oral, nonpeptide GLP-1 receptor agonist, delivers significant reductions in HbA1c and body weight—without injections and with minimal restrictions! 🌍📉 👨⚕️ 559 patients across 5 countries ⏱️ 40 weeks, 3 dosing arms (3, 12, 36 mg) 📊 HbA1c ↓ by up to 1.48%, weight ↓ up to 7.6% ✅ No severe hypoglycemia 📌 Mild GI side effects during dose titration This is a potential gamechanger for early T2DM care—simple, effective, and patient-friendly. 🚀 #Type2Diabetes #GLP1 #Orforglipron #Endocrinology #ClinicalTrials #PrecisionMedicine #Innovation #NEJM #ACHIEVE1 #OralTherapeutics 💥

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