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For users of the popular weight loss injectables Ozempic, Wegovy, Zepbound and Mounjaro, a new GLP-1 pill may be on the horizon. GLP-1 drugs have revolutionized the way the doctors treat weight loss — starting largely with Ozempic — Novo Nordisk’s blockbuster diabetes drug. But most of the current options on the market are injectables, which can be intimidating for patients to use. Eli Lilly announced Thursday that early results from a Phase 3 clinical trial of its GLP-1 pill show it reduced participants’ A1C — a measure of blood sugar control — better than a placebo. The trial lasted 40 weeks and only involved people with Type 2 diabetes. According to the company, the safety and efficacy was consistent with its injectable GLP-1 drugs, Zepbound and Mounjaro. The once-daily pill also helped patients lose up to 16 pounds.

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In the latest episode of "The Best Life Code" podcast, Dr. Rudy delve into the transformative potential of GLP1 medications, a groundbreaking discovery initially used for diabetes that is now reshaping healthcare. The conversation kicks off with exciting news about Dr. Rudy's recent talk at a Biohack Expo and his treatment work with tennis legend Serena Williams, utilizing innovative technologies for brain and body wellness. As they explore the multifaceted benefits of GLP1 medications, Dr. Rudy reveals how these "miracle drugs" could be the most significant medical breakthrough since penicillin, impacting not just weight loss but broader health aspects like anti-aging, inflammation reduction, and mental wellness. From discussions on the potential reduction of cancer risks to the enhancement of women's health issues like PCOS and menopause, the episode unfolds the vast scope of GLP1's applications. Listeners are taken on an insightful journey through the nexus of technology and health, as Dr. Rudy shares his pioneering experiences with personalized medicine and the promising future of gene editing in healthcare. Whether you're curious about the latest in biohacking or the forthcoming medical landscape, this episode is packed with forward-thinking insights that encourage a hopeful view of the future. Tune in to discover why experts believe GLP1s are poised to redefine our approach to health and longevity. Timestamps: 00:00 Psychedelics, Wellness, and Brain Health 05:18 Microplastics Impact Health Globally 07:38 GLP1 Benefits: Anti-Aging and Brain Effects 10:35 GLP1 and Cancer Risk Concerns 16:37 GLP1 Dosage and Health Benefits 18:24 Experienced Physician Adjusts Treatment for Liver Fibrosis 23:15 PCOS: Ineffective Treatments and Risks 23:52 GLP1 Revolutionizing PCOS Treatment 27:02 Sustainable Weight Maintenance Strategies 31:04 Inflammation Affects Decision-Making能力 33:58 Gyms and Clinics Partner for Health 39:16 AI and Gene Therapy Innovations 40:19 "GLP1 Pathways and Consumer Behavior" 44:46 Optimistic Healthcare Progress Discussion Quotes, Hooks, & Timestamps: "Revolutionary Discovery in Medicine": "The most important one that we've seen lately is the psychoactive effects of GLP1, meaning it acts on the brain. And it acts mostly on the dopamine, the reward centers of the brain. And we're seeing people having less reward seeking behaviors." — Doctor Rudy [00:08:19 → 00:08:34] The New Age of Anti-Aging: "I've been clamoring this for the past three, four years that this goes beyond weight loss. This is an anti aging medication." — Doctor Rudy [00:15:00 → 00:15:07] "Revolutionizing Heart Health: The Impact of GLP1 Medication": "GLP1 medication became FDA approved to reduce cardiovascular disease, heart attacks with a study that was called the select trial. And in that study they followed almost 5,000 patients who had high risk of heart disease. And they put them on GLP1 and that was a randomized placebo controlled trial. And they saw that the patients who were on GLP1 had 20% decrease in major adverse cardiovascular events." — Doctor Rudy [00:17:08 → 00:17:31] The Hidden Benefits of GLP1 Medication: "The decrease in heart disease is not just because you lose weight, because that's what we think, right? You lose weight, you have less risk of heart disease. People were getting less risk of heart disease before it happened. Why? Because GLP1 medication decrease inflammation, decrease inflammatory biomarkers, decrease insulin resistance. That is at the base of cardiovascular disease, cancer and dementia." — Doctor Rudy [00:17:46 → 00:18:10] Reversing Liver Fibrosis: "We repeated his ultrasound, it showed that his liver fibrosis by ultrasound was from stage four down to stage one. We didn't have any treatment before for fatty liver." — Doctor Rudy [00:19:03 → 00:19:15] "Long-term Weight Management Success": "Those patients never got any nutrition education. Those patients didn't get exercise education. At my practice, I see it different, that most of my patients are able to maintain most of their weight off." — Doctor Rudy [00:27:46 → 00:27:59] Gene Therapy and Behavior Change: "What I think is even the most exciting is that eventually we'll be able to do personalized medicine and AI and maybe go to the genes that produce GLP1 and kind of make that work again." — Doctor Rudy [00:39:17 → 00:39:28] "Rethinking Consumer Habits": "But the society of consumerism that we have needs to change, right? Because, for example, you look at the US Our economy is based mostly on what we consume, but we're consuming trash, so we should consume less." — Doctor Rudy [00:40:54 → 00:41:08] The Best Life Code Website - https://thebestlifecode.com/ Dr. Rudy's Website - https://drrudybestlife.com/ Dr. Rudy's Clinic's Website - https://drweightlossmiami.com/ TopHealth Media - https://tophealth.care/