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In this episode of "In the Interim..." we revisit the ground-breaking seamless phase 2/3 clinical trial for the GLP-1 agonist, dulaglutide—better known as Trulicity. We discuss the intricacies of the adaptive trial design, and the unique features that helped expedite development by 12-18 months. Listeners will gain insight into how Bayesian algorithms and innovative statistical methods were pivotal in navigating a complex trial design, benefiting Eli Lilly's pipeline and changing the landscape of diabetes treatment. Key Highlights: —Outline of the trial design and the barriers faced during its inception in 2007-2008. —Explanation of the Clinical Utility Index and its role in adaptive randomization. —The DSMB's role and interaction with Bayesian decision-making models. —Simulation-based design to optimize development efficiencies. —Insights into the predictive power of the trial on weight loss outcomes in subsequent trials. Quotes: —"The trial was run entirely by Bayesian algorithms." – Scott Berry —"They believed this utility function was absolutely the right way to go forward." – Scott Berry For more head to berryconsultants.com.

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Watch how to lose weight and keep it off for new year's resolutions with Howdini. Elizabeth Somer shares her healthy and easy weight loss tips so you can meet your new year goals! More diet and weight loss tips: https://www.youtube.com/watch?v=MFfIoU_-0Ds&index=1&list=PLC8DF339BD13D207A Subscribe to Howdini's YouTube channel: https://www.youtube.com/c/howdiniguru?sub_confirmation=1 Like us on Facebook: https://www.facebook.com/HowdiniGuru Follow us on Twitter: https://twitter.com/howdini Pin with us on Pinterest: http://www.pinterest.com/howdini This is a Howdini video about how to lose weight and keep it off as new years resolution.

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#IvanaChapman #loseweightover35 #weightlossover35 🔥 Lose fat and build muscle: Join The Lean & Strong Academy! https://bit.ly/leanandstrongYT IS 35 TOO OLD TO LOSE WEIGHT? // Once you get to a certain age, you might find that weight loss seems harder, but how can you lose weight over 35? In this video, I'll tell you what you need to focus on to keep your metabolism humming as you get older. Can you lose weight after 35? Of course! I help my online coaching clients do it all the time. There's no particular age at which weight loss becomes significantly harder, and muscle loss tends to occur due to disuse, rather than as an inevitable part of aging. Is 35 years old too old to lose weight? Nope! How about 40? No! Surely, 50 is too old to lose weight? No! The important thing with weight loss over 35 is that there are many challenges to your lifestyle. To lose weight after 35 you might need to modify your calorie intake further. Weight loss after 35 can seem harder, but it's not a significant change. I'll explain how to lose weight in your 30s and 40s because I know you want to lose weight over 35. How can you lose weight after 35? Watch the video for a simple explanation. Get Your FREE ebook! https://www.ivanachapman.com Facebook: http://bit.ly/384PjUx Twitter: https://twitter.com/IvanaChapman Instagram: https://www.instagram.com/ivana.chapman/ Disclaimer: Ivana Chapman is not a doctor or a medical professional. Always consult a physician before starting any exercise or nutrition program. Using any of this information is strictly at your own risk. Ivana Chapman will not assume any liability for direct or indirect losses or damages that may result from the use of information contained in this video including but not limited to economic loss, injury, illness or death. Is 35 Too Old To Lose Weight? https://youtu.be/63SYl5z2d6Q

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How To Lose Belly Fat video.There are many weightloss gimmicks out there. These are the 5 steps to Lose Belly Fat.. Eat good healthy foods,get plenty of exercise you enjoy doing, have fun, & get a workout partner. Follow me Ervin Ruhe Jr.& subscribe to my channel. Live workouts & more coming soon.

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Alleppey Veg Recipe for Weight Loss | Healthy Curry Recipes | South Indian Diet Plan by Richa Kharb Welcome to "Indian Weight Loss Diet by Richa"! Discover the flavors of Kerala with our Weight Loss Alleppey Veg Curry recipe. This dish is a perfect blend of wholesome vegetables and aromatic spices, designed to help you lose weight without compromising on taste. Rich in nutrients and low in calories, this curry is ideal for anyone looking to enjoy delicious meals while staying healthy. Whether you're on a weight loss journey or just love trying new, healthy recipes, this Alleppey Veg Curry is a must-try. Pair it with your favorite side for a satisfying meal! Subscribe to our channel for more weight-loss-friendly recipes, and don’t forget to like, comment, and share this video with friends and family. If you're ready to transform your body and lose up to 12 kgs in a month, WhatsApp your weight and height to +91 8956557753 and join our fastest weight loss course today! Do subscribe to our channel for more updates about your weight loss. Follow us on Instagram - https://www.instagram.com/indianweightlossdiet/ Visit our Website - https://indianweightlossdiet.com/ Download our App from Android - https://play.google.com/store/apps/details?id=com.iwldbyricha Download our App from iOS - https://apps.apple.com/in/app/indian-weight-loss-diet/id6462674579 #AlleppeyVegCurry #WeightLossRecipes #HealthyIndianFood #KeralaCuisine #IndianWeightLossDiet #RichaKharb #VegetarianWeightLoss #LowCalorieRecipes #HealthyEating #WeightLossJourney