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පර්යේෂණවලින් පෙනී යන්නේ ඉන්සියුලින් ලබා ගැනීම ආරම්භ කරන පුද්ගලයින් පළමු වසර තුළ බොහෝ විට බර වැඩි වන බවයි. සාමාන්‍ය බර වැඩිවීම රාත්තල් 4 ක් පමණ වන නමුත් සමහර පුද්ගලයින් රාත්තල් 11 ක් හෝ ඊට වැඩි විය හැකිය [1]. මෙය සිදු වන්නේ ඉන්සියුලින් ඔබේ රුධිරයේ 00:00 අධික සීනි ප්‍රමාණයක් ඇති විට මේදය ලෙස සීනි ගබඩා කිරීම ශරීරය කරන බැවිනි. 01:00 සමහර රුධිර පීඩන ඖෂධ සීනි වැඩි කළ හැක. 03:00 බර වැඩි වන විට දියවැඩියාවද වැඩි වේ. 04:30 ඉන්සියුලින් අක්මාවේ මේද තැන්පත් වීමට හේතු වේද? 05:00 නව ඖෂධ රාශියක් තිබේ. 06:00 sglt2 ඖෂධ ගැන ඔබේ වෛද්‍යවරයාගෙන් විමසන්න. 0820 ඉන්සියුලින් කුසගින්න වැඩි කරයි. 13:00 රුධිරයේ සීනි මට්ටම ඉතා පහත වැටීම වළක්වා ගැනීම සඳහා ඔබ වැඩිපුර ආහාර ගන්නවා. 17:40 ඔයාට සල්ලි තියෙනවා නම් මේ බෙහෙත ඔයාට උදව් වෙයි. 20:00 සීමිත දීමනාව: ආහාර ගැනීමෙන් පසු රුධිරයේ සීනි මට්ටම සඳහා කරන වියදම් සඳහා මුදල් ආපසු ගෙවීම. ඔබ 2 වර්ගයේ නම්, බර වැඩිවීමට හේතු නොවන තවත් බොහෝ ඖෂධ තිබේ. ඒවාට ප්‍රධාන වශයෙන් SGLT2 නිෂේධක ඖෂධ, DPP4 ඖෂධ සහ පැරණි විශ්වාසවන්ත මෙට්ෆෝමින් ඇතුළත් වේ. SGLT2 ඖෂධවලට වකුගඩු සහ හදවත ආරක්ෂා කිරීමේ අමතර ප්‍රතිලාභ ඇත. වඩාත් සවිස්තරාත්මක වීඩියෝවක් සඳහා ඉහත සබැඳියේ වීඩියෝව බලන්න. ඔබ 1 වර්ගයේ නම්, ඔබට ඉන්සියුලින් අවශ්‍ය වේ, නමුත් රනිල කුලයට අයත් බෝංචි සහ කොළ පැහැති එළවළු මත පදනම් වූ ආහාර වේලක් අනුභව කිරීමෙන් ඔබට අවශ්‍යතාවය අවම කර ගත හැකිය. ඔබ ඉන්සියුලින් ගන්නා විට, ඔබේ ශරීරය මුත්රා හරහා කැලරි නැතිවීම නතර කරයි. මෙයින් අදහස් කරන්නේ ඔබ ඔබේ ශරීරයේ වැඩිපුර කැලරි තබා ගන්නා බවයි, එය බර වැඩිවීමට හේතු විය හැක. එසේම, ඉන්සියුලින් ඔබට බඩගිනි දැනිය හැකි බැවින් ඔබට වැඩිපුර ආහාර අනුභව කළ හැකිය. SGLT-2 Inhibitors or sodium-glucose cotransporter 2 inhibitors like canagliflozin, ertugliflozin, dapagliflozin, and empagliflozin may lead to weight loss and improved blood sugar control in people with type 2 diabetes. We will go into each one of them in detail later in this video. They are approved by most governments including the Therapeutic Goods Administration or TGA in Australia, FDA in America and The Central Drugs Standard Control Organisation (CDSCO) in India. Some of the common Diabetic medications cause weight gain. They include Insulin, Sulfonylureas like glipizide, gliclazide, tolbutamide, Metiglinides like repaglinide and Thiazolidinediones like pioglitazone. Metformin is a common medication used to manage type 2 diabetes. While it wasn’t specifically designed as a weight loss drug, some studies have found a link between metformin and weight loss. Here’s what you need to know: How Metformin Works: Metformin primarily lowers blood sugar levels by reducing the amount of glucose released by the liver. It also improves insulin sensitivity, allowing muscles to use glucose more efficiently. Lower insulin levels can lead to better overall health and reduced risk of complications associated with high blood sugar. Metformin and Weight Loss: The relationship between metformin and weight loss is not fully understood, but several theories exist: Reduced Hunger Cues: Some studies suggest that metformin may affect hunger cues, leading to decreased appetite. Improved Blood Sugar Control: Better blood sugar management may indirectly contribute to weight loss. On average, people with diabetes taking metformin experience weight loss ranging from 4 to 7 pounds per year. However, individual responses can vary. Can Non-Diabetic Individuals Take Metformin for Weight Loss? Yes, metformin can be used for weight loss even if you don’t have type 2 diabetes. It is very unlikely cause hypoglycaemia in diabetics if used alone or with SGLT2 medications. Hypoglycaemia is a serious condition which can be fatal if not treated quickly. While we are in the middle of the video, it is essential to consult with a healthcare provider before starting any medication, including metformin, for weight management. SGLT2 inhibitors, also known as “gliflozins” or “flozins,” are a group of medications initially developed to manage type 2 diabetes. Their primary function is to lower blood glucose levels by increasing the excretion of glucose in the urine. However, their benefits extend far beyond glycemic control. https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or Time 8.15pm-3-Jun-14

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Semaglutide is a medication that has been generating a lot of buzz in recent years due to its potential to promote weight loss in users. Originally developed as a treatment for type 2 diabetes, semaglutide was found to have an unexpected side effect – weight loss. This discovery has led to the development of a higher-dose version of the medication specifically for weight loss, which has shown promising results in clinical trials.

How Does Semaglutide Work?

Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. These medications work by mimicking the effects of glucagon-like peptide-1 (GLP-1), a hormone that is naturally produced in the body in response to food intake. GLP-1 helps to regulate blood sugar levels by stimulating the release of insulin and decreasing the production of glucagon, another hormone that raises blood sugar levels. In addition to its effects on blood sugar levels, GLP-1 has also been shown to promote feelings of fullness and reduce appetite, which can lead to weight loss.

When semaglutide is injected, it binds to GLP-1 receptors in the body and activates them, leading to similar effects as the natural hormone. This can help to regulate blood sugar levels in individuals with diabetes and promote weight loss in those who are overweight or obese. In addition to its effects on appetite and food intake, semaglutide may also help to increase energy expenditure, or the number of calories burned at rest, which can further contribute to weight loss.

Studies have shown that individuals who take semaglutide for weight loss typically experience significant reductions in body weight compared to those who take a placebo. In one study, participants who took semaglutide lost an average of 15% of their body weight, compared to just 2.4% in the placebo group. These results were achieved in conjunction with a reduced-calorie diet and increased physical activity, which are commonly recommended for weight loss.

Potential Side Effects

While semaglutide has shown promising results for weight loss, it is not without potential side effects. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild to moderate in severity and may improve over time as the body adjusts to the medication. However, in some cases, they may persist and lead to discontinuation of the medication.

In rare cases, semaglutide may also cause more serious side effects, such as pancreatitis or kidney problems. It is important for individuals taking semaglutide to be aware of these potential side effects and to seek medical attention if they experience any symptoms of concern. In addition, individuals with a history of pancreatitis or kidney problems should use caution when taking semaglutide and consult with their healthcare provider before starting the medication.





Conclusion

In conclusion, semaglutide is a medication that has shown promise for promoting weight loss in users. By mimicking the effects of the natural hormone GLP-1, semaglutide can help to regulate blood sugar levels, reduce appetite, and increase energy expenditure, ultimately leading to weight loss. While semaglutide is generally well-tolerated, it is important for individuals to be aware of the potential side effects and to discuss any concerns with their healthcare provider before starting the medication.

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FAQ

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