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IMU-856, an orally available and systemically acting small molecule modulator that targets SIRT6 (Sirtuin 6), demonstrated a dose-dependent increase of endogenous glucagon-like peptide-1 (GLP-1) levels in a post hoc analysis of patients from its phase 1b clinical trial in celiac disease. IMU-856 also showed a dose-dependent reduction of body weight gain and food consumption in preclinical in vivo testing. These effects may indicate the potential for IMU-856 as an oral treatment option for weight management. 0:00 Opening of IMU-856 GLP-1 Webcast 1:41 Introduction 3:03 GLP-1 and Its Effects 4:44 Overview New Clinical and Preclinical Results 6:24 Preclinical In Vivo Results 7:19 Post Hoc Data from Phase 1b Celiac Disease Trial 10:36 SIRT6 Target and Gut Epithelial Cells 14:53 Obesity Market 15:47 Summary and Outlook 17:33 Q&A Session 29:58 Closing of Webcast

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Presented by http://www.beautifulonraw.com/ There are the health advantages in having late menopause. There is evidence that aging effectively accelerates once a woman has gone through menopause. I believe that, for the truly healthy woman, menopause is symptomless, and will tend to occur later in life than is presently the norm.

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The side effects go far beyond weight loss: it's reshaping culture, food habits, and society. Want to understand how health is becoming the new luxury? Check out our other videos: https://www.youtube.com/playlist?list=PLlXQ2duAcVjm2OtEx2W5cBfl8ttJzDSvK This episode of Follow the Rabbit explores the emergence of GLP-1 drugs (particularly Ozempic) as a cultural phenomenon that sits at the intersection of medical innovation, luxury consumption, and social media influence. Igor and Johannes examine how these drugs, originally developed for diabetes management, have become status symbols in the weight loss industry, raising important questions about healthcare access, the medicalization of beauty standards, and the commodification of health. Through both scientific explanation and cultural analysis, the episode reveals how GLP-1 drugs exemplify the broader trend of “health as luxury” while highlighting the complex implications for society, business, and individual well-being. Chapters 00:00 - Introduction & Overview 03:06 - The Science Behind GLP-1 08:46 - Unexpected Effects & Complications 14:21 - Manufacturing & Access Challenges 17:13 - Social Media & Marketing Impact 24:30 - The Consumerization of Healthcare 29:35 - Broader Societal Implications 33:02 - Industrial Food Complex Discussion 36:49 - Closing Thoughts --------------- You can also listen to this episode on Apple, Spotify or wherever you get your podcasts. Follow the Rabbit on Spotify at https://podcasters.spotify.com/pod/show/follow-the-rabbit Follow the Rabbit on Apple at https://podcasts.apple.com/au/podcast/follow-the-rabbit/id1763655913 Follow the Rabbit on YouTube at https://www.youtube.com/channel/UCXKCXmFazhd1SZxoawCku0w Follow the Rabbit is a Known Unknowns production Known Unknowns on YouTube at https://www.youtube.com/@knownunknowns-xyz Known Unknowns on Instagram at https://www.instagram.com/knownunknowns.xyz/ 📧 Write to us at [email protected] Follow the Rabbit is hosted by Igor Schwarzmann & Johannes Kleske Find out more about Igor Schwarzmann at https://igorschwarzmann.com Find out moire about Johannes Kleske at https://johanneskleske.com

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Extra fat in your thighs can make simple tasks difficult like walking or going up a flight of stairs that is why it's necessary to focus on this part of the body as well. Today's workout video is an exercise that focuses on your legs and thighs, enabling you to work your lower body muscles to burn the excess fat and tone your muscles as you go along. Each routine included in the video lasts for about 1 minute making the whole video last for 23 mins including rest times! 😀 If you're ready to make that change and get into gear, let's begin the workout today! Good luck and keep exercising everyday until you see results!💪❤️ **If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Sunday to Friday!

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Watch the full episode: https://www.youtube.com/watch?v=MpSunlBeHTg Today, I’m joined by Dr. Andrew Brandeis, co-founder & CEO of OK Capsule, a private-label supplement manufacturer and distributor for DTC wellness brands. Meticulously formulated and scientifically backed, Dr. Brandeis and team have developed 70+ supplements that prioritize quality, transparency, and efficacy, providing companies and their clientele with a custom wellness solution through daily vitamin packs. Subscribe to the podcast → insider.fitt.co/podcast Subscribe to our newsletter → insider.fitt.co/subscribe Follow us on LinkedIn → linkedin.com/company/fittinsider/ OK Capsule Website: okcapsule.com Andrew’s Email: [email protected] - The Fitt Insider podcast is brought to you by Jack Taylor, our exclusive PR partner. More than just PR, they’re creative storytellers and brand builders who actually understand the health and wellness industry. Learn more and get in touch at JackTaylorPR.com/Fitt