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Why is metformin being used in patients without diabetes who are on antipsychotics like olanzapine or risperidone? In this episode, we break down the new clinical guidelines on how and when to use metformin to prevent or treat weight gain caused by antipsychotic medications. Check out the video here! https://www.youtube.com/watch?v=pdDwtZFzwmA 👂 Have you seen metformin used this way? Drop your experience in the comments—let's learn from each other. 📚 References: Carolan A, Hynes-Ryan C, Agarwal SM, et al. Metformin for the prevention of antipsychotic-induced weight gain: guideline development and consensus validation. Schizophr Bull. 2024; Published online Dec 9, 2024. PsychiatryOnline. Metformin can be used to prevent or treat antipsychotic-induced weight gain. https://psychiatryonline.org/doi/10.1176/appi.pn.2025.02.2.8 American Psychiatric Association (APA). Practice Guideline for the Treatment of Patients With Schizophrenia. Aoife Carolan, Caroline Hynes-Ryan, Sri Mahavir Agarwal, Rita Bourke, Walter Cullen, Fiona Gaughran, Margaret K Hahn, Amir Krivoy, John Lally, Stefan Leucht, John Lyne, Robert A McCutcheon, Michael J Norton, Karen O’Connor, Benjamin I Perry, Toby Pillinger, David Shiers, Dan Siskind, Andrew Thompson, Donal O’Shea, Dolores Keating, Brian O’Donoghue, Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation, Schizophrenia Bulletin, 2024;, sbae205, https://doi.org/10.1093/schbul/sbae205 ⚠️ Important Note: This video is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider before starting or changing medications. 📢 Disclaimer: The images used in this video are for educational/informational purposes only and belong to their respective owners. No copyright infringement is intended. ============================================================ #Metformin #Antipsychotics #WeightGain #PharmacyEducation #PharmacistLife #MentalHealthMedications #SchizophreniaTreatment #BipolarDisorder #Clozapine #Olanzapine #Quetiapine #Risperidone Metformin for antipsychotic-induced weight gain, metformin and antipsychotics, metformin weight gain prevention, metformin schizophrenia, metformin bipolar disorder, metformin olanzapine, metformin quetiapine, metformin risperidone, metformin clozapine, antipsychotic weight gain treatment, metformin guidelines 2024, metformin dosing for weight gain, metformin side effects, metformin and GLP-1 agonists, metformin and lifestyle changes, metformin for adolescents on antipsychotics, metformin and metabolic syndrome, off-label use of metformin, metformin and psychiatric medications, metformin and insulin resistance, metformin and appetite suppression

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(10 Jan 2006) 1. Wide of exteriors of surgery ward at Polyclinic Hospital Umberto I 2. Exterior of balloon procedure room 3. Room with nurses preparing for balloon inserting procedure 4. Balloon procedure kit 5. Pan down from inflated balloon to a flat one 6. Close up of medical information card 7. Inflated balloon 8. Wide of a surgery room 9. Chief surgeon Nicola Basso preparing for surgery 10. Close up of medical machine 11. SOUNDBITE (Italian) Nicola Basso, Chief surgeon at Polyclinic Hospital Umberto I and Director of balloon procedures: ''It's an endoscopic procedure, which means it doesn't need a general anaesthesia. with an instrument that's usually used to practice endoscopy, a 1/2 litre volume balloon is inserted and is inflated inside the stomach. It occupies a part of the stomach and it slows down stomach emptying. All this produces a lack of appetite, a satiated feeling, all of which makes easier for the patient to lose weight.'' 12. Balloon procedure kit 13. Procedure room with doctors and a patient ready to be operated 14. SOUNDBITE (Italian) Vittorio Campati, Patient ''I'm 140 kilos. With the intragastric balloon I hope to lose weight.'' 15. Doctor preparing drip bottle 16. Sedated patient on operation table 17. Flat balloon is inserted through the patient's mouth 18. Images of the patient's stomach on screen as doctors carry out procedure 19. Doctor's hands inflating balloon, which is inside stomach 20. Endoscopy camera shot of stomach 21. Endoscopy camera inserted through the patient's mouth 22. Various of doctors looking to the endoscopy images of balloon inflating 23. Patient awaking after 10 minute operation 24. Simona Spalliera, patient, walking down hall to show her weight loss 25. SOUNDBITE (Italian) Simona Spalliera, 33 years old patient: ''I've kept the balloon for six months - six months and a half. I weighed 100 hundred kilos. Naturally I stopped measuring my weight because I was so demoralised that I didn't want to know it anymore. I have now lost around 30 kilos.'' 26. Wide of exteriors of Polyclinic Hospital Umberto I SUGGESTED LEAD-IN: After holidays full of too much food and plenty of drink - many people include "losing weight" in the list of new year's resolutions. In Italy, a new medical procedure is making this goal much easier for some to obtain. A balloon is inserted into the stomach and inflated so that patients feel full and eat less. VOICE-OVER: The New Year often brings an appetite for the latest diet fads and exercise regimes in the hopes of shedding a few extra pounds. In Italy, achieving that weight loss could be a bit easier with new "anti-obesity" balloons. These balloons are inserted in the stomach in a simple procedure to give the feeling of being full. And if you feel full, you're likely to eat less which will lead to weight loss. Italian surgeon, Nicola Basso, has been testing the procedure in Rome at the Polyclinic Hospital Umberto I since 1998. He says the procedure is only minimally invasive. SOUNDBITE (Italian) ''It's an endoscopic procedure, which means it doesn't need a general anaesthesia. With an instrument that's usually used to practice endoscopy, a 1/2 litre volume balloon is inserted and is inflated inside the stomach. It occupies a part of the stomach and it slows down stomach emptying. All this produces a lack of appetite, a satiated feeling, all of which makes easier for the patient to lose weight.'' SUPER CAPTION: Nicola Basso, chief surgeon at Polyclinic Hospital Umberto I The balloon contains blue coloured liquid, in order to detect possible leaks. Find out more about AP Archive: http://www.aparchive.com/HowWeWork Twitter: https://twitter.com/AP_Archive Facebook: https://www.facebook.com/APArchives ​​ Instagram: https://www.instagram.com/APNews/ You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/4fa92418b57e86a220a99fcb19b90de1

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