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Scientific knowledge of the gut microbiome has increased exponentially over the last decade. Recently, several studies have suggested that specific strains of bacteria, including Akkermansia muciniphila, are key to supporting the environmental conditions required for other related bacterial strains that facilitate healthy metabolic health. In this video, Colleen Cutcliffe, PhD, co-founder and CEO of Pendulum discusses groundbreaking research around Akkermansia mucinophila, the role of short-chain fatty acids (SCFAs) in stimulating GLP-1 pathways, implications for diabetes management, and how gut bacteria influence inflammation, gut integrity, and overall metabolic health. They also explore how diet, antibiotics, and stress impact the microbiome, potential roles of probiotics in inflammatory bowel disease (IBD), pediatric gut health, and exciting emerging research on the gut-brain axis and neurological conditions like Parkinson's disease. Colleen highlights Pendulum's rigorous scientific approach, including clinical trials and innovative manufacturing practices that ensure product viability and effectiveness. Promotional code STERLING20 can be applied for 20% off of first membership purchases (https://pendulumlife.com). Please note that Dr. Sterling has no financial affiliation with Pendulum. This code is provided only as a discount to listeners and does not constitute a clinical recommendation or medical advice. Chapters: - 00:00 Intro: Gut Microbiome Essentials - 02:03 Pendulum's Biotech Innovation - 06:15 GLP-1 & Metabolic Health - 09:59 Probiotic Industry Insights - 17:17 Importance of Akkermansia - 24:17 Clinical Results for Diabetes - 29:28 Manufacturing Challenges - 39:13 Diet's Impact on Microbiome - 43:35 Gut-Brain Connection - 46:50 Next Steps & Resources Spotify Channel: https://podcasters.spotify.com/pod/show/sterlingmdphd/ Social & Website: Instagram - https://www.instagram.com/sterlingmdphd X - https://x.com/sterlingmdphd Facebook - / sterlingmdphd Newsletter - http://eepurl.com/hQpdqT Apple Podcasts: https://apple.co/3y438C9 References & Show Notes: http://www.nicksterling.com/ This content is not medical advice, is for general information purposes only, and does not constitute the practice of medicine or any other healthcare professional services. No doctor-patient relationship is formed. This content is not a substitute for medical evaluation or treatment and does not take precedence over information provided to you by your healthcare provider or official public health sources. Please visit http://nicksterling.com/terms for full Terms of Use.

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Struggling with weight gain on GLP1 meds? Here’s what I did this week, what’s changing, and why I’m not panicking. The GLP1 Girl Code → A real community for women on GLP-1s, with support, monthly drops, and everything I’ve learned so far in one place. → https://stan.store/nykboku/p/the-glp1-girl-code Start here (it’s free): The GLP1 Girl Starter Guide – the starter guide that actually prepares you. → https://nykboku.myflodesk.com/osm Want my CUSTOM FOOD DIARY GPT? Grab it here. https://nykboku.myflodesk.com/fooddiary Need a free community? The GLP1 Girl Community – free weekly weigh-ins and support from women who get it. → https://www.facebook.com/share/g/1DBnZfA8td/ Not on GLP1 yet? Amble makes it simple to get started (if you qualify) → https://enroll.joinamble.com/start-online-visit/commercial?referral-campaign=heyitsnyk&referral-source=affiliate Instagram: daily life, tips, and everything that doesn’t make it into YouTube → https://www.instagram.com/theglp1girlcode Tracking App I Use: Pep App – code NYK77 for discount https://apps.apple.com/us/app/pep-glp-1-shot-ozempic-tracker/id6504788281 The Things I Use (and love): ♡ My GLP1 Supplement Routine: https://www.theglp1girlcode.com/supplements IUGA Activewear: https://www.theiuga.com/?ref=fuqkooax Silly George Lashes: https://glnk.io/932p/nykweighsin15 The Scale I use: https://www.amazon.com/dp/B09HCJD6H1?ref=t_ac_view_request_product_image&campaignId=amzn1.campaign.2H5OLZCQ7O36E&linkCode=tr1&tag=josephineboku-20&linkId=amzn1.campaign.2H5OLZCQ7O36E_1749501023224 🎥 Filming Setup: https://amzn.to/4hY4zWL --- I'm Nyk, and I create videos to document my weight loss journey, share what’s working, and build a community of women who are taking their lives back, one step at a time. If there’s ever a topic you want me to cover or a question you have, drop it in the comments. I’d love to hear from you. xo, Nyk --- 📩 Want even more support? I send weekly emails with real talk, tips, and encouragement to help you stay consistent — without being perfect. 📬 Join the list when you grab the free guide → https://nykboku.myflodesk.com/osm --- 📌 Disclaimer: This content is based on my personal experience and is not medical advice. Always consult your doctor before starting any medication. #GLP1Journey #WeightLossTips #Semaglutide #GLP1ForWeightLoss #RealWeightLossStory #MounjaroJourney #glp1support

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Standing abs are underrated? Not anymore! This routine will work your core, improve your posture, and will get your waist trimmed, all done while staying on your feet. Great for those who wants to lose those stubborn belly fat but also looking for a more fun workouts rather than just doing those crunches on the floor. So whether you’re new to working out or trying something different, you can add this to your routine and make this one a solid way to start your journey. With a series of standing cardio and core workouts, we got some nice moves like Hip Swirls, Squats, Side Kicks, and many more. This routine builds on the last, and it gives your core a complete sculpt while also being gentle on your knee joints. So if you’re searching for a good belly workout to work on your core and drop those stubborn belly fat, this is it! This one is for you! So stay motivated and keep up with your schedule. Stay consistent and keep it up. Check your daily diet and make sure it is aligned with your goals. Good luck and have fun! ❤️💪 **Don’t forget to share your experience and progress in the comment section. If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Monday to Saturday! TIMECODES: 00:00 Introduction 00:15 Body Rotations 00:52 Rest 01:08 High Knee Chops Left 01:38 Rest 01:54 High Knee Chops Right 02:24 Rest 02:40 Hip Swirls 03:12 Rest 03:28 High Knee Jacks 03:54 Rest 04:10 Forward Calf Raises 04:53 Rest 05:09 Knee Drive 05:33 Rest 05:49 Lateral Steps 06:20 Rest 06:36 Knee Raises 07:02 Rest 07:18 Lateral Taps 07:43 Rest 07:59 Leg Kicks 08:26 Rest 08:43 Oblique Twist Squat 09:30 Rest 09:46 Overhead Reach 10:13 Rest 10:29 Rise And Plie 11:22 Rest 11:38 Side Leg Raise Left 12:21 Rest 12:37 Side Leg Raise Right 13:21 Rest 13:37 Side Deep Squats 14:21 Rest 14:37 Slow Jumping Jacks 15:03 Rest 15:19 Squat Arm Lifts 15:49 Rest 16:05 Standing Crunch 16:46 Rest 17:02 Squat And Kick 17:45 Rest 18:01 Torso Twists 18:38 Rest 18:54 Victory Squat 19:27 Rest 19:43 Waist Pinchers Left 20:18 Rest 20:34 Waist Pinchers Right 21:08 Rest 21:24 Windmill 22:04 Rest 22:27 Body Rotations 23:03 Rest 23:19 High Knee Chops Left 23:49 Rest 24:05 High Knee Chops Right 24:35 Rest 24:51 Hip Swirls 25:23 Rest 25:39 High Knee Jacks 26:06 Rest 26:22 Forward Calf Raises 27:04 Rest 27:20 Knee Drive 27:45 Rest 28:01 Lateral Steps 28:32 Rest 28:48 Knee Raises

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Hey y’all! Totally different content than I’m used to filming but I had so many requests for this type of video. Let me know if you’d like to see more! *MENTIONS* How I lost 40 pounds: https://youtu.be/8mDWfRwUNqA (How I calculate my calories is in this video too!) American Eagle haul: https://youtu.be/GlAKTIH_ucM *DINNER RECIPE* (I didn’t do butter or Ritz crackers) Chicken breasts (shredded) 1 bag of boil in bag rice 1 can cream of chicken 1 can cream of mushroom 8oz sour cream Onion powder 1/2 bag cheese Butter 1/2 stick Mix all together Cook 350° 45mins Take out, add other half bag of cheese Mix other half of stick butter (melted) with 1 pack ritz crackers and spread on top. Bake 10 more minutes Thanks for watching (and reading 😊) These types of videos are well out of my comfort zone but I hope it’s helpful. I see a lot of people struggling to understand weight loss and how to go about it. As I said in this video, portion sizes and moderation will go a long way. Figure out your calories first - then start weighing and measuring everything. Slow and steady wins the race ❤️

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