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When it comes to weight loss medications, semaglutide has been making waves in the medical world. With the recent approval of oral semaglutide, patients now have the option to choose between the traditional injectable form of the medication and the new oral form. Both versions of semaglutide have been shown to be effective in promoting weight loss, but there are some key differences between the two that patients should be aware of before making a decision. In this article, we will compare oral semaglutide to injectable semaglutide to help you determine which option may be right for you.
Effectiveness of Oral Semaglutide vs. Injectable Semaglutide
Both oral and injectable semaglutide have been shown to be effective in promoting weight loss in patients who are overweight or obese. Injectable semaglutide is typically administered once a week, while oral semaglutide is taken in pill form once a day. Studies have shown that both versions of the medication can lead to significant weight loss when combined with a healthy diet and exercise program.
One study published in the New England Journal of Medicine found that patients who took injectable semaglutide for 68 weeks lost an average of 15% of their body weight, compared to just 2.4% in the placebo group. Another study on oral semaglutide showed similar results, with patients losing an average of 14.9% of their body weight over 68 weeks.
Side Effects of Oral Semaglutide vs. Injectable Semaglutide
Like any medication, both oral and injectable semaglutide can cause side effects in some patients. Common side effects of injectable semaglutide include nausea, diarrhea, and constipation. These side effects are usually mild and tend to subside over time as the body adjusts to the medication.
On the other hand, oral semaglutide may be associated with a higher risk of gastrointestinal side effects, such as nausea and vomiting, compared to the injectable form. However, some patients may prefer the convenience of taking a pill once a day over having to administer a weekly injection.
Cost Comparison of Oral Semaglutide vs. Injectable Semaglutide
Cost is another important factor to consider when choosing between oral and injectable semaglutide. Injectable semaglutide tends to be more expensive than oral semaglutide, both in terms of the medication itself and the cost of supplies needed to administer the injection.
While some insurance plans may cover both forms of semaglutide, patients should check with their provider to see what their out-of-pocket costs will be. In some cases, patients may find that oral semaglutide is a more affordable option, especially if they are not comfortable with administering injections themselves.
Convenience and Accessibility of Oral Semaglutide vs. Injectable Semaglutide
When it comes to convenience, oral semaglutide may have the upper hand. Taking a pill once a day is generally easier for patients than having to remember to administer a weekly injection. Oral semaglutide can also be taken without any special training, whereas injectable semaglutide requires patients to learn how to properly administer the injection.
Accessibility is another factor to consider. While injectable semaglutide may require a prescription and a visit to the doctor’s office to receive the injection, oral semaglutide can be picked up at a pharmacy without the need for a doctor’s visit. This may make oral semaglutide a more attractive option for some patients.
Long-Term Success Rates of Oral Semaglutide vs. Injectable Semaglutide
Long-term success rates of oral and injectable semaglutide have not been well-studied, as both medications are relatively new to the market. However, initial studies have shown promising results for both forms of the medication.
Patients who are able to stick to a healthy diet and exercise program while taking semaglutide are likely to see long-term benefits in terms of weight loss and overall health. It is important for patients to work closely with their healthcare provider to monitor their progress and make any necessary adjustments to their treatment plan.
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http://www.DoctorsToTrust.com @doctorstotrust presents episode 2606 | Dr BEN BIKMAN + expert panel Metabolic Health Summit Metabolic Health Summit panel Q&A… Ben Bikman: question on GLP1 drugs: in early research in low dose as anti-diabetic drug, had been lukewarm -primary mechanism of action: glucagon inhibition for one with hyperglycemia, this was a good way of bringing that down -at higher dose, primary mechanism of action is stomach paralysis [much less enthusiastic] One of the mechanism of improving insulin sensitivity from GLP1 drugs could be an induction of adipocyte hyperplasia [vs hypertrophy]. A sister version of the most popular one has been shown to activate hyperplasia [Liraglutide] How? You can be making new fat cells [hyperplasia] and still lose weight due to stomach paralysis… Concern about long term use of drug: substantial reduction of lean mass— again, due to stomach paralysis The day they want to get off of that drug…consider: middle age woman, lost both fat and lean mass on drug -also have increased number of fat cells -off drug: the fat mass will Easily return But, not all negative: If one can use lowest possible dose, and follow low carb diet--they can be fine |||||||||||||||||||||||||||||||| doctorstotrust.com metabolichealthsummit.com benbikman.com original video on here: https://youtu.be/J_AFik8DMoM?si=XHvwjwLJsYeG3o6g We do not use corruptible, epidemiological survey research as causal science. For each short/sharable video, the original Youtube links are provided above. None of this content is intended to be individual, personalized medical advice. We hope you find value for yourself in these videos & find them easy to share with loved ones! DISCLAIMER The DoctorsToTrust videos are for general informational purposes only and do not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
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In this episode of Sensible Health Solutions, Dr. Luper takes a deep dive into GLP-1 medications—a hot topic in the world of weight management and diabetes treatment. He breaks down how these medications work in the body, what makes them effective, and the potential benefits and side effects. Whether you're curious about GLP-1 for managing blood sugar levels or looking for a better understanding of its role in weight loss, this episode provides clear, evidence-based information to help you navigate this treatment option. Join Dr. Luper as he uncovers the science behind GLP-1 medications and what it means for your health. This content is for informational purposes only and is not a substitute for professional medical advice, treatment or diagnosis. Seek medical attention from a healthcare professional for any medical conditions.
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