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Professor Barry Borlaug presents the SUMMIT trial on the use of the GIP / GLP-1 receptor dual agonist in patients with obesity-associated Heart-Failure with Preserved Ejection Fraction, which has been published in New Engl J Med 2024 and elected the most important study in cardiology and lipidology 2024 by MARKUS at HOMe. Dr. Borlaug is Professor of Medicine and Director, Circulatory Failure Research, Division of Cardiovascular Diseases, and Chair for Research, Division of Circulatory Failure, Department of Cardiovascular Medicine at the Mayo Clinic, Rochester, Minnesota. He is a global leader in studies on mechanisms, diagnosis and treatment of heart failure, particularly heart failure with preserved ejection fraction (HFPEF). The interview was recorded on January 16th, 2025. Moderators: Prof. Dr. Dr. Stephan Schirmer (Kaiserslautern, Germany), Prof. Dr. Florian Custodis (Saarbrücken, Germany) and Prof. Dr. Gunnar Heine (Frankfurt, Germany). Articles discussed: GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders. Leggio L, Hendershot CS, Farokhnia M, Fink-Jensen A, Klausen MK, Schacht JP, Simmons WK. Nat Med 2023 doi: 10.1038/s41591-023-02634-8 Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. Kramer CM, Borlaug BA, Zile M MR, Ruff D, DiMaria JM, Menon V, Ou Y, Zarante AM, Hurt KC, Murakami M, Packer M; SUMMIT Trial Study Group. J Am Coll Cardiol 2024 doi: 10.1016/j.jacc.2024.11.001 Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA; SUMMIT Trial Study Group. N Engl J Med 2024 doi: 10.1056/NEJMoa2410027 Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial. Borlaug BA, Zile MR, Kramer CM, Baum SJ, Hurt K, Litwin SE, Murakami M, Ou Y, Upadhyay N, Packer M. Nat Med 2024 doi: 10.1038/s41591-024-03374-z Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction. Obokata M, Reddy YNV, Pislaru SV, Melenovsky V, Borlaug BA. Circulation 2017 doi: 10.1161/CIRCULATIONAHA.116.026807 An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score. Reddy YNV, Carter RE, Sundaram V, Kaye DM, Handoko ML, Tedford RJ, Andersen MJ, Sharma K, Obokata M, Verbrugge FH, Borlaug BA. Nat Med 2024 doi: 10.1038/s41591-024-03140-1 A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. Circulation 2018 doi: 10.1161/CIRCULATIONAHA.118.034646 How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Pieske B, Tschöpe C, de Boer RA, Fraser AG, Anker SD, Donal E, Edelmann F, Fu M, Guazzi M, Lam CSP, Lancellotti P, Melenovsky V, Morris DA, Nagel E, Pieske-Kraigher E, Ponikowski P, Solomon SD, Vasan RS, Rutten FH, Voors AA, Ruschitzka F, Paulus WJ, Seferovic P, Filippatos G. Eur J Heart Fail 2020 doi: 10.1002/ejhf.1741 Dapagliflozin Enhances Arterial and Venous Compliance During Exercise in Heart Failure With Preserved Ejection Fraction: Insights From the CAMEO-DAPA Trial. Tada A, Burkhoff D, Naser JA, Harada T, Pourmussa B, Reddy YNV, Jensen MD, Carter RE, Demmer RT, Testani JM, Chirinos JA, Borlaug BA. Circulation 2024 doi: 10.1161/CIRCULATIONAHA.124.068788 Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial. Borlaug BA, Reddy YNV, Braun A, Sorimachi H, Omar M, Popovic D, Alogna A, Jensen MD, Carter R Circulation 2023 doi: 10.1161/CIRCULATIONAHA.123.065134
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Are you looking for a delicious and convenient way to incorporate keto-friendly supplements into your daily routine? Look no further than Keto F1 Gummies! These chewy treats are packed with essential nutrients to help support your keto lifestyle. In this comprehensive guide, we will explore everything you need to know about Keto F1 Gummies, including their benefits, ingredients, and how to incorporate them into your diet.
Benefits of Keto F1 Gummies
Keto F1 Gummies offer a wide range of benefits for those following a ketogenic diet. These tasty treats are a convenient way to supplement your diet with essential nutrients that may be lacking in your regular meals. They are also a great option for those who struggle to swallow pills or simply prefer a more enjoyable way to get their daily dose of vitamins and minerals.
In addition to their convenience, Keto F1 Gummies are formulated to support your keto lifestyle. They are low in carbs and sugar, making them an ideal choice for those looking to maintain ketosis. Plus, they are packed with nutrients like B vitamins, electrolytes, and antioxidants to help keep you feeling energized and healthy.
Another key benefit of Keto F1 Gummies is their versatility. Whether you need a boost of energy before a workout or a quick snack on the go, these gummies can provide the support you need. With their delicious fruity flavors, they make taking your daily supplements a treat rather than a chore.
Ingredients in Keto F1 Gummies
Keto F1 Gummies are made with high-quality ingredients that are carefully selected to support your keto lifestyle. These gummies are free from artificial colors, flavors, and preservatives, making them a wholesome choice for your daily supplement regimen. Some key ingredients found in Keto F1 Gummies include:
– B Vitamins: Essential for energy production and overall health.
– Electrolytes: Help maintain proper hydration and muscle function.
– Antioxidants: Protect cells from damage and support immune health.
How to Incorporate Keto F1 Gummies Into Your Diet
There are several ways to incorporate Keto F1 Gummies into your daily routine. One simple option is to enjoy them as a tasty snack between meals. These gummies can help curb cravings and keep you feeling satisfied without derailing your keto diet.
Another way to use Keto F1 Gummies is as a pre-workout supplement. The B vitamins and electrolytes in these gummies can help boost your energy levels and enhance your performance during exercise. Simply enjoy a few gummies before your workout for an added burst of energy.
You can also take Keto F1 Gummies with your morning coffee or tea as a convenient way to start your day on a healthy note. These gummies can help support your energy levels and mental clarity throughout the day, making them a great addition to your morning routine.
Frequently Asked Questions About Keto F1 Gummies
Q: Are Keto F1 Gummies suitable for vegetarians and vegans?
A: Yes, Keto F1 Gummies are free from animal-based ingredients and are suitable for vegetarians and vegans.
Q: How many gummies should I take each day?
A: The recommended dosage of Keto F1 Gummies may vary, so it’s best to follow the instructions on the packaging or consult with a healthcare professional.
Q: Can I take Keto F1 Gummies if I have dietary restrictions?
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A: Keto F1 Gummies are designed to be keto-friendly and are free from common allergens like gluten and dairy, making them suitable for many dietary restrictions.
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Maggie Beer has long been a household name in the culinary world. Known for her delicious recipes and passion for quality ingredients, Maggie has now turned her attention to the popular Keto diet. With her latest cookbook, “Maggie Beer Keto Weight Loss: Chef’s Special Recipes for Keto Success,” Maggie has created a collection of recipes that are not only low in carbs but also delicious and satisfying.
How Maggie Beer Keto Recipes Can Help You Achieve Weight Loss Success
One of the biggest challenges of following a Keto diet is finding meals that are both satisfying and low in carbs. Maggie Beer’s recipes are designed to help you stay on track with your weight loss goals while still enjoying delicious meals. By using high-quality ingredients and simple cooking techniques, Maggie shows that eating Keto doesn’t have to be complicated or boring.
Each recipe in Maggie’s cookbook is carefully crafted to be not only delicious but also nutritious. By focusing on whole foods and fresh ingredients, Maggie’s recipes help you fuel your body with the nutrients it needs to thrive. Whether you’re looking for a quick and easy dinner or a decadent dessert, Maggie has you covered with her Keto-friendly recipes.
One of the things that sets Maggie’s recipes apart is her focus on flavor. By using a variety of herbs, spices, and seasonings, Maggie ensures that every dish is bursting with taste. Whether you’re a fan of spicy foods or prefer something more mild, Maggie’s recipes offer something for everyone. With Maggie’s recipes, you’ll never feel like you’re missing out on flavor while following a Keto diet.
Benefits of Using Maggie Beer’s Keto Recipes
There are many benefits to using Maggie Beer’s Keto recipes to support your weight loss journey. Not only are her recipes delicious and satisfying, but they can also help you stay on track with your diet goals. By providing easy-to-follow recipes with simple ingredients, Maggie makes it easy to stick to your Keto diet without feeling overwhelmed.
Another benefit of using Maggie’s recipes is that they can help you save time and money. Many of her recipes can be made in under 30 minutes, making them perfect for busy weeknights. Additionally, Maggie’s focus on using seasonal ingredients can help you save money at the grocery store while still enjoying delicious meals.
By incorporating Maggie’s recipes into your meal plan, you can also improve your overall health and well-being. The Keto diet has been shown to have numerous health benefits, including weight loss, improved energy levels, and better mental clarity. With Maggie’s delicious recipes, you can enjoy the benefits of the Keto diet without feeling deprived or restricted.
How to Incorporate Maggie Beer’s Keto Recipes Into Your Meal Plan
If you’re looking to incorporate Maggie Beer’s Keto recipes into your meal plan, there are a few key tips to keep in mind. First, be sure to plan ahead and make a list of ingredients you’ll need for the week. This can help you stay organized and ensure you have everything you need to make Maggie’s delicious recipes.
Another tip for incorporating Maggie’s recipes into your meal plan is to batch cook and meal prep. By preparing ingredients in advance and cooking in large batches, you can save time and ensure you always have a Keto-friendly meal on hand. Maggie’s recipes are perfect for meal prep, as many of them can be stored in the fridge or freezer for later use.
Lastly, don’t be afraid to experiment and make Maggie’s recipes your own. While Maggie provides detailed instructions for each recipe, feel free to add your own twist or substitutions to suit your taste preferences. With Maggie’s versatile and flavorful recipes, the possibilities are endless for creating delicious meals that support your weight loss goals.
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FAQ About Maggie Beer’s Keto Weight Loss Cookbook
1. Are Maggie Beer’s Keto recipes suitable for beginners?
Yes, Maggie’s recipes are perfect for beginners looking to start their Keto journey. With simple ingredients and easy-to-follow instructions, Maggie’s recipes are accessible to cooks of all skill levels.
2. Can I use Maggie Beer’s recipes for long-term weight loss maintenance?
Absolutely! Maggie’s recipes are designed to be both delicious and nutritious, making them perfect for long-term weight loss maintenance. By incorporating a variety of flavors and ingredients, Maggie’s recipes can help you stay on track with your healthy eating goals.
3. Are Maggie’s recipes family-friendly?
Yes, Maggie’s recipes are designed to appeal to a wide range of tastes and preferences, making them perfect for families. Whether you’re cooking for picky eaters or adventurous foodies, Maggie’s recipes offer something for everyone.
4. Can I customize Maggie’s recipes to fit my dietary restrictions?
Yes, many of Maggie’s recipes can be easily customized to fit a variety of dietary restrictions. Whether you’re gluten-free, dairy-free, or vegetarian, Maggie’s recipes can be adapted to suit your needs while still being delicious and satisfying.
5. Where can I purchase Maggie Beer’s Keto Weight Loss cookbook?
Maggie Beer’s Keto Weight Loss cookbook is available for purchase online and in select bookstores. You can also find some of Maggie’s recipes on her website and social media channels for free inspiration and resources.
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KetoBlast is a revolutionary dietary supplement that has taken the world by storm, transforming the way people approach weight loss and overall health. With its explosive results and loyal following, KetoBlast has become a popular choice for those looking to shed pounds and improve their well-being. By following a ketogenic diet, users of KetoBlast have experienced incredible transformations in their bodies, leading to increased energy, improved mental clarity, and rapid fat loss.
The Science Behind KetoBlast
KetoBlast works by putting the body into a state of ketosis, where it burns fat for fuel instead of carbohydrates. This process is achieved by limiting the intake of carbohydrates and increasing the consumption of healthy fats and proteins. By doing so, the body begins to burn stored fat for energy, resulting in rapid weight loss and a host of other health benefits. The key ingredient in KetoBlast is Beta-Hydroxybutyrate (BHB), which is a ketone that helps the body enter into ketosis more quickly and efficiently.
Users of KetoBlast often report feeling more energized and focused throughout the day, as ketones are a cleaner and more efficient source of energy than glucose. Additionally, ketosis has been shown to have a number of other benefits, such as reducing inflammation, improving insulin sensitivity, and even potentially reducing the risk of certain chronic diseases.
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When starting a ketogenic diet with KetoBlast, it is important to gradually reduce your carbohydrate intake while increasing your consumption of healthy fats and proteins. It is also recommended to drink plenty of water and engage in regular exercise to maximize the effects of KetoBlast. Many users find that tracking their macronutrient intake and keeping a food diary can help them stay on track and achieve their weight loss goals.
KetoBlast is available in convenient supplement form, making it easy to incorporate into your daily routine. Simply take the recommended dosage with a glass of water, preferably in the morning or before a meal. Many users find that taking KetoBlast before a workout helps to boost their energy levels and increase fat burning during exercise.
The Results Speak for Themselves
Countless users have experienced incredible transformations with KetoBlast, shedding stubborn pounds and achieving their weight loss goals in record time. Many report feeling more confident, energetic, and in control of their health after incorporating KetoBlast into their lives. With its powerful combination of natural ingredients and proven results, KetoBlast has become a trusted ally in the quest for optimal health and well-being.
Whether you are looking to lose weight, improve your energy levels, or simply enhance your overall health, KetoBlast offers a safe and effective solution that delivers real results. Join the KetoBlast community today and experience the transformative power of ketosis for yourself!
Frequently Asked Questions
Q: Is KetoBlast safe to use?
A: KetoBlast is made with all-natural ingredients and is considered safe for most users. However, it is always recommended to consult with a healthcare professional before starting any new supplement regimen.
Q: How quickly will I see results with KetoBlast?
A: Results with KetoBlast can vary from person to person, but many users report seeing significant improvements within the first few weeks of use. Consistency with diet and exercise is key to maximizing the effects of KetoBlast.
Q: Can I take KetoBlast if I have dietary restrictions?
A: KetoBlast is suitable for most dietary restrictions, as it is gluten-free, dairy-free, and non-GMO. However, if you have specific allergies or sensitivities, it is best to check the ingredients list before using KetoBlast.

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Are you looking to kick start your weight loss journey and achieve your dream body? Luxe Keto ACV could be the solution for you. This revolutionary weight loss supplement combines the power of keto and apple cider vinegar to help you burn fat faster and more efficiently than ever before. In this comprehensive overview, we will take a closer look at Luxe Keto ACV, including how it works, what ingredients it contains, and the potential benefits it can offer. Read on to discover if Luxe Keto ACV is the right choice for you.
How Does Luxe Keto ACV Work?
Luxe Keto ACV works by harnessing the power of ketosis and apple cider vinegar to help your body burn fat for energy instead of carbs. When you take Luxe Keto ACV, your body enters a state of ketosis, where it begins to use stored fat as its primary source of fuel. This can lead to rapid weight loss and increased energy levels, making it easier for you to stick to your diet and exercise routine.
Apple cider vinegar is also a key ingredient in Luxe Keto ACV, as it has been shown to support weight loss by increasing feelings of fullness and reducing cravings. Additionally, apple cider vinegar can help regulate blood sugar levels, improve digestion, and boost immune function.
By combining the power of keto and apple cider vinegar, Luxe Keto ACV provides a comprehensive approach to weight loss that can help you achieve your goals faster and more effectively than ever before.
Ingredients of Luxe Keto ACV
Luxe Keto ACV is made with a blend of natural ingredients that have been scientifically proven to support weight loss and improve overall health. The key ingredients in Luxe Keto ACV include:
– BHB (Beta-Hydroxybutyrate): BHB is a ketone body that helps your body enter and maintain ketosis, making it easier to burn fat for energy.
– Apple Cider Vinegar: Apple cider vinegar has been shown to support weight loss by increasing feelings of fullness, reducing cravings, and improving digestion.
– Green Tea Extract: Green tea extract is rich in antioxidants and can boost metabolism, promote fat burning, and improve overall health.
Potential Benefits of Luxe Keto ACV
There are many potential benefits of taking Luxe Keto ACV as part of your weight loss journey. Some of the key benefits of Luxe Keto ACV include:
– Rapid Weight Loss: By promoting ketosis and increasing fat burning, Luxe Keto ACV can help you lose weight quickly and efficiently.
– Increased Energy Levels: When your body burns fat for energy instead of carbs, you may experience a significant boost in energy levels, making it easier to stay active and motivated.
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