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We explore GLP-1 and GIP receptor agonists like Tirzepatide (Zepbound, Mounjaro), discussing their mechanism, appetite regulation, fat loss benefits, and how they're absorbed and metabolized. Always consult a healthcare provider before use. #GLP1 #GIP #Tirzepatide #Zepbound #Mounjaro #WeightLoss #Metabolism #AppetiteRegulation #ObesityTreatment #Healthcare
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What if We're Using GLP-1 Medications All Wrong? Drugs like Ozempic, Wegovy, and Mounjaro are transforming the landscape of medical weight loss, but could their side effects be a sign that we’re not harnessing their full therapeutic potential? In this eye-opening conversation, Dr. Ben Bikman, metabolic health researcher and professor at BYU, joins Dr. Bret Scher to explore a powerful new framework: using GLP-1 medications at low doses and for short durations to help curb carbohydrate cravings, break addictive eating cycles, and support long-term metabolic health. Rather than prescribing high doses indefinitely, Dr. Bikman proposes a more targeted approach: - Microdosing GLP-1s to enhance satiety and reduce cravings for processed carbs - Using the medication as a temporary metabolic tool to support transitions to lower-carb diets - Reducing long-term risks such as muscle loss, mood changes, and diminishing effectiveness - Emphasizing the importance of habit change, insulin regulation, and muscle preservation This conversation reimagines GLP-1s not as a lifelong solution, but as a catalyst for sustainable, low-insulin lifestyles, aligned with ketogenic and metabolic therapies. 📌 Could a 90-day microdosing protocol replace years of medication? Learn how this metabolic-first strategy could empower patients to reclaim their health, without becoming dependent on medication for life. #GLP1 #Ozempic #Wegovy #Mounjaro #BenBikman #MetabolicHealth #Microdosing #InsulinResistance #LowCarbDiet #KetogenicTherapy #MedicalWeightLoss #BretScher #MetabolicMind *Expert Featured:* - Dr. Benjamin Bikman - https://x.com/BenBikmanPhD - benbikman.com - insuliniq.com *Papers/Articles Mentioned:* -https://www.washingtontimes.com/news/2025/may/27/microdosing-glp-1-drugs-could-solve-americas-carbohydrate-crisis/ -https://pubmed.ncbi.nlm.nih.gov/8984033/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ *About us:* Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. *Timestamps:* 0:00 - What if we’re using GLP-1s all wrong? 1:40 - Dr. Benjamin Bikman’s interest in metabolic health and GLP-1s 3:20 - Unexpected side effect of GLP-1s 5:26 - Are GLP-1s actually beneficial? 10:55 - The difference between “weight loss” and metabolic health 15:10 - The role of cravings and satiety signals 19:58 - Dr. Bikman’s ideal use of GLP-1s 24:14 - “Self-discipline in a syringe” 25:11 - Are all weight loss interventions beneficial? 27:20- New studies examining microdosing GLP-1s 32:12 - Learn more about Dr. Bikman
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📄 Abstract: _ Recent research suggests that increasing ketones in the blood, either through a ketogenic diet or ketone supplements, may help women with irregular menstrual cycles regain regularity. _ In a controlled trial, 11 out of 13 pre-menopausal women on a keto diet reported improvements in menstrual frequency and intensity, with some women even resuming menstruation after prolonged absence. 🔬 Process: _ Participants: 19 pre-menopausal, healthy but overweight women, aged approximately 34. _ Groups: Participants were divided into three groups: keto diet alone, keto diet with ketone supplements, and a low-fat diet. _ Duration: All participants followed a six-week intervention, with researchers providing meals to ensure consistency. _ Assessments: Lifestyle and menstrual cycle data were gathered through biweekly surveys and self-reports. ⚙️ Results: _ Menstrual Impact: 85% of women on a keto diet noticed menstrual changes, regardless of weight loss. Menstruation Resumed: Six women who hadn’t menstruated for over a year began having periods. _ Ketones as Key Factor: The study suggests ketone presence, not weight loss, influenced menstrual regulation. _ Individualized Effect: While some women saw benefits from ketone supplements, effects varied, hinting at individualized responses. 🔍 Source: Institutions: The Ohio State University, Metagenics Inc. Funding: Seed funds from Ohio State University’s Department of Human Sciences and supplements provided by Metagenics Inc. Journal: PLOS ONE