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GLP-1 Agonists for Obesity in Non-Diabetic Patients: Game Changer or Overhyped? | A Critical Clinical Review GLP-1 receptor agonists are reshaping the treatment landscape for obesity—even in patients without diabetes. But are they truly a game-changing intervention or an overhyped pharmacologic trend with major limitations? In this comprehensive analysis, we critically examine the clinical efficacy, cardiovascular outcomes, safety profile, real-world limitations, and economic impact of GLP-1 agonists—drawing from major trials like SELECT, SURMOUNT, and recent meta-analyses. We compare leading agents including semaglutide, tirzepatide, and emerging triple agonists such as retatrutide. You'll learn: How GLP-1 RAs affect appetite, energy homeostasis, and cardiovascular risk Differences in weight loss efficacy among GLP-1 agents in non-diabetic populations Long-term adherence challenges and the risks of weight regain The emerging safety landscape, including GI side effects and perioperative risks Cost-effectiveness concerns, access barriers, and global policy considerations Who is this for? This lecture is designed for physicians, pharmacists, endocrinologists, obesity specialists, and healthcare leaders seeking a balanced, evidence-based perspective on the role of GLP-1s in modern obesity treatment. Whether you're prescribing these agents or designing treatment protocols, this session offers vital insights into optimizing use and anticipating future directions. 🎯 Is it a breakthrough or just hype? We present the evidence—so you can decide. 📌 Subscribe to GlobalRPh for more in-depth clinical content on pharmacotherapy, metabolic health, and practice-changing evidence.
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My week 3 weight loss results on Zepbound ( Tirzepatide, GLP-1, Mounjaro ) I also discuss body cavitation and wood therapy. And my reward for this week! #zepbound #tirzepatide #mounjaro #tirzepatideweightloss #weightlossjourney #glp1 #symptoms 🍍 MENTIONED IN VIDEO 🍍 https://amzn.to/4aFbi5V https://www.weightwatchers.com/us/pla... Body Cavitation https://youtu.be/FDQ3ywF1MJg?si=mvolboSB5VmlsTaw https://youtu.be/0DJWy3N-eJ8?si=_d8UsUlx1p1bDh22 https://youtu.be/k_HbGz75yoI?si=raMKf_JT3Vr5jGhN ________________________________________________________________________ 🍍 OTHER RELATED VIDEOS 🍍 HOW I PREPARED THE WEEK BEFORE TAKING ZEPBOUND/TIRZEPATIDE https://youtu.be/tzlJY_ZXOGI?si=F640pY57HJ6bV9YT My First Time Injecting Zepbound! Did it hurt? https://youtu.be/KaWA99TkNdg?si=f6OyDx4N7TaIt92U Morning After Taking First Zepbound Shot! Any Side Effects? https://youtu.be/SlhigwrAKVg?si=BbXEaeKukYGOksgG Easy Way to Get More Water on Tirzepatide | Zepbound | To Help Relieve Symptoms https://youtu.be/W4hpGqDBm28?si=gg3_ES_nQrIk96Q- 24 HOURS AFTER ZEPBOUND SHOT | DID I LOSE ANY WEIGHT? https://youtu.be/GMr3zLTYvdo?si=RlpvCySGHgFiwWlb How to Get Your Protein! For Tirzepatide / Zepbound! https://youtu.be/HLg2XEB-eVY My Second Time Injecting Zepbound! Weight Loss Update! Was it Easier? https://youtu.be/AzUfKXUkNUg How to Get Zepbound Using Weight Watchers Clinic: Timeliness & Experience | GLP-1's | Mounjaro https://youtu.be/YYB2ETpskKE ________________________________________________________________________ 🍍 HELPFUL LINKS 🍍 https://pmc.ncbi.nlm.nih.gov/articles.... https://investor.lilly.com/news-relea... https://pmc.ncbi.nlm.nih.gov/articles... ________________________________________________________________________ 🍍 ELI LILLY SAVINGS CARD 🍍 https://zepbound.lilly.com/coverage-s... ________________________________________________________________________ 🍍 ALL SOCIALS 🍍 https://linktr.ee/beewildhomestead ________________________________________________________________________ SHOP LINKS! 🍍 FOLLOW & SHOP MY AMAZON STORE 🍍 https://amzn.to/4grY5Pa _______________________________________________________________________ DISCLAIMER: Some links are affiliate links, meaning I earn a small commission from your purchase which helps me and my channel out and I definitely appreciate it and you! The price is no different for you :) FTC Disclaimer Required for all Influencers: I am a content creator and an Amazon Influencer. I am also a partner or affiliate with multiple brands. I partner with brands to gain discounts, samples, and provide giveaways for my audience. Some of the links posted throughout my sites I may earn commission from by you making purchases or utilizing the codes for a discount for yourself (This does not increase the price for you). Thank you for doing so, this really helps my channel and to provide quality content for you! 00:00 Introduction 01:38 3 Week weight loss result 03:41 Getting a home body cavitation system 07:18 Reward for weight loss 11:56 2nd part of reward 14:20 Taking dance classes
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• Get faster with TrainerRoad: https://goo.gl/RHTG3p • Submit your training question: https://goo.gl/pkY3GN • Open description box for a list of topics covered in this episode • Subscribe to the podcast: https://goo.gl/kWYZs9 // TOPICS COVERED IN THIS EPISODE • How to burn fat with cycling • What is “spot-burning” for fat? • What is the difference between visceral and subcutaneous fat • Why food matters more than training for fat burning • What role intensity plays in losing weight • How insulin and sugar affect fat loss • Why athletes have a surprisingly complex time with weight control • Testosterone and cyclists • Is hormone replacement therapy banned for cyclists? • Why taking testosterone is cheating • Natural ways to increase testosterone production • What effect sleep has on testosterone • Should cyclists always avoid weight gain? • How cyclists can ad weight that helps make them faster • Why cyclists should strength train • Why sugary drinks can be bad for cyclists • The difference between hydration during a race and recovery • What is osmolality and why you should keep track of it • Which nutrition products optimize hydration • How mountain bikers can improve their pacing • Why mountain bike races start so hard • How to train your body to start races hard • Coach Chad's favorite books // ABOUT THE PODCAST The Ask a Cycling Coach is the only podcast dedicated to making you a faster cyclist. Each week Coach Chad, Coach Jonathan and TrainerRoad’s CEO Nate answer your cycling and triathlon training questions. • Watch more livestreams: https://goo.gl/tmuYhE • Listen to all podcast episodes on: → Apple Podcasts: https://apple.co/2zdeBTt → Soundcloud: https://goo.gl/SBUx5Y → Spotify: https://goo.gl/knr2zS → Google Play: http://bit.ly/2u2pt0O → Stitcher: https://goo.gl/HqbVVb → Overcast: https://goo.gl/Ct83nR // BECOME A FASTER CYCLIST TrainerRoad gives you structured indoor workouts, science-backed training plans, and simple performance-focused analytics tools. • Check out features: https://goo.gl/zbF4G7 • Download the app: https://goo.gl/XDqPTn • Browse training plans: https://goo.gl/21qJjz // WATCH NEXT (A FEW OF OUR BEST VIDEOS) • The Chase: An Inside Look at What It Takes to Be The Best: https://goo.gl/DQcJJT • Strength Training for Cyclists: https://goo.gl/4DHoab • 5 Stretches Every Cyclist Should Know: https://goo.gl/yLBoZ5 • How to Become a Faster Mountain Biker” https://goo.gl/H15V3G • Is Higher Cadence Better, How Crank Length Affects Power & More: https://goo.gl/8H7HiU // CONNECT WITH OTHER CYCLISTS • Join the Ask a Cycling Coach podcast Facebook Group: https://goo.gl/dfGxjo • Get details on new & unreleased features in the TR Beta Testers Group: https://goo.gl/m5om6f // STAY IN TOUCH • Subscribe to YouTube channel: https://goo.gl/M2N6yJ • Facebook: https://goo.gl/QTQrEt • Instagram: https://goo.gl/15AR5g • Twitter: https://goo.gl/Ue9j6m • Strava Club: https://goo.gl/qryRTt • Reddit: https://goo.gl/cqfrTk
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🚨 Compounded GLP-1 Update! 🚨 March 19th was supposed to be the end, but you can STILL find compounded Tirzepatide at Orderly Meds! If you’re looking for a GLP-1 compound update, this is one of the only places left selling it. #GLP1CompoundUpdate #CompoundTripeptide #Tirepizide #Trizapedite #CompoundPharmacy #GLP1 #SemaglutideCompound #CompoundedMedication #tirzepatide
