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The Servier pharmaceutical group was found guilty by a Paris court on Monday, as the trial over one of the biggest health scandals to have hit France came to a close. More than ten years after the opening of a judicial investigation and eighteen months after the start of the trial, the drugmaker was found guilty of involuntary manslaughter and aggravated fraud for selling the weight loss pill 'Mediator,' which was blamed for hundreds of deaths. "It was a historic trial, it becomes for me, a historic judgment. Even if it is not entirely satisfactory, it is nonetheless true that this is the first time that a laboratory has been so severely condemned," said victims' lawyer Jean-Christophe Coubris. "I hope that the laboratories will hear both the suffering of the victims and the condemnation that has been pronounced against the Servier laboratories," the lawyer added. "Servier laboratories are ordered to pay the victims around 160 million euros (188 million USD). This is extremely low compared to the real profit made by the Mediator, around 400 million euros (470,9 million USD) during the 14 years of undue marketing," said Charles-Joseph-Oudin, lawyer of Michel Due, one of the victims. Servier was also sentenced to a fine of 2.7 million euros (3,18 million USD). Jean-Philippe Seta executive of Servier pharmaceutical group was sentenced to four years of suspended imprisonment, as well as a fine of 90,600 euros (106,67 USD). At least 500 people died of heart valve problems due to the Mediator's active ingredient, according to France's health ministry. The drug was on the market for 33 years before it was pulled in 2009. Credit: Ruptly #pharma #servier #mediator

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Weight loss is a common goal for many individuals, whether it be for health reasons, personal appearance, or overall well-being. With the rise of obesity rates globally, pharmaceutical companies have been working diligently to develop drugs that can aid in weight loss. Two of the newest medications on the market, Semaglutide and Tirzepatide, have shown promise in helping individuals achieve their weight loss goals. In this article, we will compare the two drugs in terms of their effectiveness, side effects, and overall impact on weight loss.

Semaglutide: A Breakthrough in Weight Loss Medication

Semaglutide is a medication that was originally developed to treat type 2 diabetes. However, during clinical trials, it was discovered that Semaglutide also had a significant impact on weight loss. The medication works by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and appetite. In studies, Semaglutide has been shown to help individuals lose an average of 10-15% of their body weight, making it one of the most effective weight loss medications on the market.

One of the key benefits of Semaglutide is its ability to not only help individuals lose weight, but also keep it off long-term. Many weight loss medications on the market only provide short-term results, with individuals often gaining back the weight once they stop taking the medication. However, studies have shown that individuals who take Semaglutide are able to maintain their weight loss even after stopping the medication, making it a valuable tool for those looking to make lasting changes to their health and well-being.

Like any medication, Semaglutide does come with potential side effects. Some of the most common side effects of Semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication. It is important for individuals to talk to their healthcare provider before starting Semaglutide to discuss any potential side effects and determine if the medication is right for them.

Tirzepatide: A New Player in the Weight Loss Arena

Tirzepatide is another medication that has shown promise in helping individuals lose weight. Like Semaglutide, Tirzepatide was originally developed as a treatment for type 2 diabetes but has since been found to have significant weight loss benefits. Tirzepatide works by targeting multiple hormone pathways in the body, helping to regulate blood sugar levels and appetite.

In clinical trials, Tirzepatide has been shown to help individuals lose an average of 10-12% of their body weight, making it a strong contender in the weight loss medication market. One of the key advantages of Tirzepatide is its flexibility in dosing, with individuals able to adjust their dose based on their weight loss goals and individual response to the medication.

While Tirzepatide is generally well-tolerated, it does come with potential side effects. Some of the most common side effects of Tirzepatide include nausea, diarrhea, and injection site reactions. Like Semaglutide, these side effects are usually mild and tend to improve over time. It is important for individuals to work closely with their healthcare provider when starting Tirzepatide to monitor for any potential side effects and adjust the dose as needed.

Comparing Semaglutide and Tirzepatide: Which is Right for You?

When comparing Semaglutide and Tirzepatide, it is important to consider a few key factors. Both medications have been shown to be effective in helping individuals lose weight, with average weight loss ranging from 10-15% for Semaglutide and 10-12% for Tirzepatide. However, the medications work in slightly different ways, with Semaglutide mimicking the effects of GLP-1 and Tirzepatide targeting multiple hormone pathways in the body.

In terms of side effects, both Semaglutide and Tirzepatide have similar profiles, with common side effects including nausea, diarrhea, and injection site reactions. It is important for individuals to talk to their healthcare provider about any potential concerns or side effects before starting either medication. Additionally, individuals should consider their individual weight loss goals and lifestyle factors when choosing between Semaglutide and Tirzepatide, as each medication may work better for different individuals based on their unique needs and preferences.

Overall, both Semaglutide and Tirzepatide are valuable tools in the fight against obesity and can help individuals achieve their weight loss goals. Individuals should work closely with their healthcare provider to determine which medication is right for them and develop a comprehensive weight loss plan that includes healthy eating, regular physical activity, and ongoing support from healthcare professionals.

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