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How Do Ozempic and Wegovy Work? Ozempic and Wegovy are synthetic GLP-1 molecules named Semaglutide. Ozempic is approved for type II diabetes mellitus and protection against cardiac events in type II DM patients. Wegovy is approved for weight loss in obese and overweight individuals and for protection against cardiac events in obese and overweight individuals. Let's review the mechanism of action and the side effects of these drugs. If you like this content and want more, click here: https://www.drbeen.com/med-nerd Want to join my uncensored talks? Join me on patreon or substack: Patreon: https://www.patreon.com/mobeensyed?fan_landing=true Substack: https://mobeensyedmd.substack.com/ Want to support this work?: BuyMeACoffee: https://www.buymeacoffee.com/drmobeensyed PayPal: https://paypal.me/mobeensyed?locale.x=en_US #drbeen #koolbeens #Weight_Loss Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight | FDA https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or Ozempic for weight loss: Does it work, and what do experts recommend? https://health.ucdavis.edu/blog/cultivating-health/ozempic-for-weight-loss-does-it-work-and-what-do-experts-recommend/2023/07 Semaglutide delays 4-hour gastric emptying in women with polycystic ovary syndrome and obesity - PubMed https://pubmed.ncbi.nlm.nih.gov/36511825/ The metabolic role of vagal afferent innervation | Nature Reviews Gastroenterology & Hepatology https://www.nature.com/articles/s41575-018-0062-1 Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow | American Journal of Physiology-Gastrointestinal and Liver Physiology https://journals.physiology.org/doi/full/10.1152/ajpgi.1998.275.5.G984 Wegovy® Pen Instructions | Wegovy® (semaglutide) Injection 2.4 mg https://www.wegovy.com/taking-wegovy/how-to-use-the-wegovy-pen.html Incretin https://en.wikipedia.org/wiki/Incretin Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms - PubMed https://pubmed.ncbi.nlm.nih.gov/9357836/ Give the Receptor a Brake: Slowing Gastric Emptying by GLP-1 | Diabetes | American Diabetes Association https://diabetesjournals.org/diabetes/article/63/2/407/34120/Give-the-Receptor-a-Brake-Slowing-Gastric-Emptying GLP-1 Localisation and Proglucagon Gene Expression in Healthy and Diabetic Mouse Ileum - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200298/#:~:text=For%20instance%2C%20proglucagon%20is%20cleaved,13%2C%2016%2C%2027). What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell? - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218725/ Glucagon-Like Peptide-1 Receptor Agonists for Chronic Weight Management - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533252/ Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow | American Journal of Physiology-Gastrointestinal and Liver Physiology https://journals.physiology.org/doi/full/10.1152/ajpgi.1998.275.5.G984 Why Ozempic Causes Diarrhea and How to Manage Your Symptoms - GoodRx https://www.goodrx.com/ozempic/diarrhea Wegovy (Semaglutide): Uses, Side Effects & Weight Loss https://www.drugwatch.com/drugs/wegovy/#:~:text=Wegovy%20carries%20a%20black%20box,same%20effects%20occur%20in%20humans. Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss | Gastroenterology | JAMA | JAMA Network https://jamanetwork.com/journals/jama/fullarticle/2810542 The metabolic role of vagal afferent innervation | Nature Reviews Gastroenterology & Hepatology https://www.nature.com/articles/s41575-018-0062-1 What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell? - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218725/ Enteroendocrine cell - Wikipedia https://en.wikipedia.org/wiki/Enteroendocrine_cell#:~:text=in%20the%20duodenum.-,L%20cell,in%20the%20duodenum%20and%20jejunum. What is ilial brake? inslag.indd https://scholarlypublications.universiteitleiden.nl/access/item%3A2956466/view Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483000/#:~:text=Distinct%20neuronal%20cell%20populations%2C%20particularly,glucose%20metabolism%20and%20energy%20expenditure.
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How do we ensure that we are losing body fat using our Peloton? Cardio is a tool we can use to help increase the caloric deficit which also has some fantastic benefits. When should you increase the time and intensity of your cardio? The plan to follow will be based on your response to your current session. I prefer walking on my incline treadmill to burn body fat, to lose stubborn lower back and lower belly fat but any form of movement can be beneficial. HIIT cardio has some great benefits but it may not be the best option when the goal is merely fat loss. Start with the Peloton, break a sweat and burn body fat to reach your goals!
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The Keto Biolife diet has taken the health and wellness world by storm, promising to transform your body and improve your overall well-being through the power of bio-life innovation. This revolutionary approach to weight loss and health focuses on maximizing fat burning and optimizing energy levels by shifting the body’s primary fuel source from carbohydrates to fats. By following a high-fat, low-carb diet, Keto Biolife enthusiasts have reported significant weight loss, increased energy, improved mental clarity, and a host of other benefits.
Understanding the Keto Biolife Diet
The Keto Biolife diet is based on the principle of ketosis, a natural metabolic state in which the body burns fat for fuel instead of carbohydrates. By drastically reducing your carb intake and increasing your consumption of healthy fats, you can enter ketosis and start burning stored fat for energy. This can lead to rapid weight loss and improved body composition, as well as a reduction in inflammation and better control of blood sugar levels.
While following the Keto Biolife diet, it’s important to focus on whole, unprocessed foods such as meat, fish, eggs, nuts, seeds, and low-carb vegetables. Avoiding processed foods, sugar, grains, and high-carb snacks is key to staying in ketosis and reaping the benefits of this innovative approach to health and wellness.
Many people find that the Keto Biolife diet is not only effective for weight loss, but also helps them feel more focused, alert, and energized throughout the day. By fueling your body with healthy fats and avoiding spikes in blood sugar, you can achieve a more stable and sustained level of energy that can carry you through your daily activities with ease.
The Science Behind Keto Biolife
The Keto Biolife diet is backed by decades of research on the benefits of low-carb, high-fat diets for weight loss and overall health. Studies have shown that ketosis can help improve insulin sensitivity, decrease inflammation, and promote fat loss while preserving lean muscle mass. By adhering to the principles of the Keto Biolife diet, you can tap into your body’s natural ability to burn fat for fuel and achieve lasting results.
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One of the key factors that sets the Keto Biolife diet apart from other weight loss programs is its focus on bio-life innovation. By incorporating cutting-edge research on the microbiome, metabolism, and cellular health, Keto Biolife offers a comprehensive approach to transforming your body from the inside out. By nourishing your body with nutrient-dense foods and supporting your metabolism with targeted supplementation, you can optimize your health and unlock your full potential.
Whether you’re looking to lose weight, boost your energy levels, or improve your overall well-being, the Keto Biolife diet offers a unique and effective solution. By harnessing the power of bio-life innovation, you can transform your body and achieve your health and fitness goals like never before.
Frequently Asked Questions About Keto Biolife
Q: Is the Keto Biolife diet safe for everyone to follow?
A: While the Keto Biolife diet can be effective for many people, it’s important to consult with a healthcare provider before making any significant changes to your diet or lifestyle. Individuals with certain medical conditions or dietary restrictions may need to modify the Keto Biolife approach to suit their individual needs.
Q: How quickly can I expect to see results on the Keto Biolife diet?
A: Results can vary depending on individual factors such as metabolism, activity level, and adherence to the diet protocol. Some people may experience rapid weight loss and increased energy within the first few weeks of following the Keto Biolife diet, while others may take longer to see significant changes in their body composition and overall health.
Q: Can I exercise while following the Keto Biolife diet?
A: Yes, exercise can be an important component of a healthy lifestyle and can complement the effects of the Keto Biolife diet. However, it’s important to listen to your body and adjust your physical activity levels as needed to support your energy levels and overall well-being while following the diet.
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Semaglutide is a medication that is currently being utilized in weight loss programs for individuals struggling with obesity. This medication has shown promising results in helping patients achieve significant weight loss, but like any other medication, it comes with its own set of side effects that users should be aware of. Understanding these side effects is crucial for individuals considering incorporating semaglutide into their weight loss journey.
Common Side Effects
Some of the common side effects associated with semaglutide include nausea, vomiting, diarrhea, and constipation. These gastrointestinal side effects are typically mild to moderate in severity and tend to improve over time as the body adjusts to the medication. It is important for individuals to monitor these side effects and consult their healthcare provider if they become bothersome or persistent.
Another common side effect of semaglutide is decreased appetite, which can be both a benefit and a challenge for individuals trying to lose weight. While reduced appetite can aid in weight loss efforts, it is important for individuals to ensure they are still consuming adequate nutrients to meet their body’s needs. Monitoring food intake and consulting a nutritionist may be beneficial in managing this side effect.
In some cases, individuals may experience injection site reactions with semaglutide, such as redness, swelling, or itching at the injection site. These reactions are usually mild and resolve on their own. Proper injection technique and site rotation can help minimize the risk of these reactions.
Rare Side Effects
While most individuals tolerate semaglutide well, there are some rare but serious side effects that have been reported. These include pancreatitis, gallbladder disease, kidney problems, and allergic reactions. It is important for individuals taking semaglutide to be aware of these potential risks and promptly report any unusual symptoms to their healthcare provider.
Another rare but potentially serious side effect of semaglutide is hypoglycemia, or low blood sugar. This can occur in individuals taking other medications that lower blood sugar levels, such as insulin or sulfonylureas. Monitoring blood sugar levels closely and adjusting medications as needed can help prevent hypoglycemia while taking semaglutide.
There have been reports of thyroid tumors in animal studies with semaglutide, although the relevance to humans is not clear. Individuals with a history of thyroid cancer or other thyroid problems should discuss the potential risks and benefits of semaglutide with their healthcare provider before starting treatment.
Conclusion
Overall, understanding the potential side effects of semaglutide is essential for individuals embarking on a weight loss journey with this medication. By being aware of these side effects and closely monitoring their symptoms, individuals can minimize risks and maximize the benefits of semaglutide in their weight loss program. Consulting a healthcare provider and following their guidance can help ensure a safe and effective experience with semaglutide.
