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Dr. Zachary Knight and Dr. Andrew Huberman discuss the development of GLP-1 drugs like Ozempic for diabetes and weight loss, examining their historical origins, biological mechanisms, and impact on appetite and metabolism. Dr. Zachary Knight is a professor of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute (HHMI) investigator. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast. Watch the full episode: https://youtu.be/C5KpIXjpzdY Show notes: https://www.hubermanlab.com/episode/dr-zachary-knight-the-science-of-hunger-medications-to-combat-obesity Timestamps 00:00 Introduction to Weight Loss Challenges 00:06 The Discovery of GLP-1 & Its Origins 01:35 Understanding the Incretin Effect 02:58 The Role of GLP-1 in Diabetes Treatment 04:39 Challenges & Innovations in GLP-1 Drug Development 05:52 Breakthroughs in GLP-1 Drugs for Weight Loss 10:47 Mechanisms of GLP-1 Drugs in the Brain 13:39 Conclusion & Further Insights #HubermanLab #Science #GLP1 Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

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http://skilltutorials.com/FatLossSupplement The body fat that you hold under your skin is stored in adipocytes, also known as fat cells. To lose body fat, these cells must be as small as possible, so you need to empty the fat cells of most of their contents. There are several fat burning supplements for men that do just that, increasing your ability to lose fat while still doing the same exercises. Caffeine is a potent one and a great weight loss supplement for men and women. Most likely you associate caffeine with the buzz you get in the morning or the fact that it can seriously ramp up your fat burning efforts. This works the best when caffeine is taken just before a workout. Take 200 -- 400 mg of caffeine between meals, 2 to 3 times per day or 30 minutes before workouts. Yohimbe is the active ingredient found in the bark from a West African tree, which aids in libido boosting as well as fat loss by increasing the amount of fat that gets released from your fat cells, similar to caffeine. It is one of the more powerful natural fat burning supplements for men around. Take enough yohimbe to provide 5-20mg of yohimbine per dose, two to three times per day; one dosage should be consumed 30-60 minutes prior to training-day workouts. Calorie Burners Just because supplements like caffeine and yohimbe help free up more fat from your fat cells, that doesn't necessarily mean that it will be burned off for good. Most natural fat burning supplements only work on one facet of your biology, but when combined they are a super fat loss combination. You also need to ramp up your calorie burn, which forces your body to use that freed-up fat as a fuel source. These four ingredients will boost the number of calories your body burns, kissing that extra few pounds of weight good-bye. Green Tea Extract Green tea extract is a real no-brainer. It aids fat loss by boosting the number of calories you burn each day. The active ingredients in green tea responsible for the fat-burning effect are catechins, particularly one known as epigallocatechin gallate (EGCG). Take about 500-1,000mg of green tea extract standardized for EGCG two to three times per day. Take one of those dosages 30-60 minutes prior to training-day workouts. These are just a sample of some of the more powerful fat burning supplements for men that nature has provided for us. Taken individually, they lose a lot of their power, but when used synergistically they take on a much more powerful form. Share this video: http://www.youtube.com/watch?v=36dGz_coIOc http://youtu.be/36dGz_coIOc Subscribe: http://www.youtube.com/user/bodybuildallday Tags: fat burning supplements for men best fat burning supplements for men fat burning supplements best fat burning supplement fat burning pills fat burning food fat burning diet fat burning drinks good fat burning supplements best fat burning exercise

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Amgen shares experienced their steepest decline in over two decades as results from their experimental weight-loss drug, MariTide, failed to surpass Wall Street's high expectations. Despite showing promise with an average 20% weight loss in a year-long trial, analysts noted MariTide’s results were only on par with drugs already approved from Novo Nordisk and Eli Lilly, such as Ozempic, Wegovy, and Mounjaro. Amgen's drug also showed slightly higher side effects, contributing to the market’s disappointment. Amgen Shares Plunge After Weight-Loss Drug Misses Expectations | News Today | AF14 #Amgen #MariTide #WeightLoss #StockMarket #NovoNordisk #EliLilly #Ozempic #Medicare #Medicaid #Biotech Talks Shows Central brings the latest in news, lifestyle programs, comic and political Talk Shows, Such as, Black & White, Nadeem Malik Live, Red Line, Gup Shab Nay Had Kar Di and more to your screens. Subscribe and never stay behind on the newest developments from across the country Talk Shows Central YouTube Channel is managed by Dot Republic Media, All Copyrights Reserved. Subscribe to our channel for all the latest updates: http://bit.ly/TalkShowsCentralYT Like our Facebook page: https://www.facebook.com/TalkShowsCentral/

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