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GLP1 agonists (GLP1a), including semaglutide and tirzepatide, were initially developed for diabetes mellitus (DM) management but are increasingly used for obesity. Female factor infertility has been found to improve after exposure to GLP1a, though it is unclear if the effect is related to obesity or other drug effects. The impact of GLP1a on male factor infertility has not been fully described. This study sought to assess improvements in semen analysis (SA) parameters in men with abnormal SA, while controlling for DM and body mass index (BMI), to determine the improvement attributable to GLP1a exposure. Read the full abstract: https://www.auajournals.org/doi/10.1097/01.JU.0001110004.96669.db.06

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Berberine is a bioactive compound found in several plants, including barberry, goldenseal, and Chinese goldthread. It has gained attention for its potential health benefits. Here are 10 notable benefits of berberine: 1. Blood Sugar Regulation: Berberine has been shown to help lower blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver. This makes it a popular supplement for managing type 2 diabetes. 2. Cholesterol and Lipid Management: Research suggests that berberine can help lower total cholesterol, LDL (bad) cholesterol, and triglycerides while increasing HDL (good) cholesterol levels, contributing to heart health. 3. Weight Loss Support: Berberine may aid in weight loss by improving metabolism and promoting fat loss. Some studies indicate that it can help reduce body mass index (BMI) and waist circumference. 4. Anti-Inflammatory Properties: Berberine has demonstrated anti-inflammatory effects, which can help reduce inflammation in the body and may benefit conditions characterized by chronic inflammation. 5. Antimicrobial Effects: Berberine exhibits antimicrobial properties against various bacteria, viruses, and fungi. It has been studied for its potential in treating infections and supporting gut health. 6. Gut Health Improvement: Berberine may help balance gut microbiota and improve digestive health, potentially alleviating symptoms of gastrointestinal disorders and supporting overall gut function. 7. Cardiovascular Health: By improving lipid profiles, reducing blood pressure, and exerting anti-inflammatory effects, berberine may contribute to better cardiovascular health and reduced risk of heart disease. 8. Cancer Research: Preliminary studies suggest that berberine may have anti-cancer properties, inhibiting the growth of certain cancer cells and enhancing the effectiveness of some chemotherapy drugs. 9. Potential Neuroprotective Effects: Some studies indicate that berberine may have neuroprotective effects, potentially benefiting cognitive function and offering protection against neurodegenerative diseases. 10. Hormonal Balance: Berberine may play a role in regulating hormones, particularly insulin and glucose metabolism, which can be beneficial for individuals with polycystic ovary syndrome (PCOS) and other hormonal imbalances. Denwalker.com mm Twitter=@drdenwalker YouTube: Dr. Dennis Walker @dr.denniswalker6588 Twitter @drdenwalker

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Is your BODY TYPE - The Stress/Cortisol Body Type? Do you have kind of a Chubby Face, Belly Fat, or Back Fat? Then you need to watch this Video to understand Cortisols role in your Body; the good, the bad & the Ugly roles it plays. First, Cortisol has a vital physiological role By raising plasma glucose levels at times of stress, providing the body with the energy it needs to face bodily attacks from injury, illness or infection. Now, Too much cortisol for too long can have serious, negative effects. The tissue breakdown, reduced protein synthesis and conversion of protein to glucose can decrease musculature and increase abdominal fat. It also suppresses levels of growth hormone and sex hormones, which can reduce libido and fertility. It lessens glucose usage and increases blood levels potentially predisposing to diabetes.   Now, Exercise is perceived by the body as a form of stress and stimulates the release of cortisol. In general, the more your fitness improves the better the body becomes at dealing with physical stress. However, research shows that the time and intensity of exercise can affect the level of cortisol release. When it comes to exercise, more may not be better.  Training for more than 60 minutes, even at a low intensity will burn up the body’s glycogen stores and stimulate cortisol release. Long-term cortisol exposure was significantly higher in endurance athletes. Short high intensity exercise such as sprints, HITT or weight training cause less of an increase in plasma cortisol concentrations. However, the levels tend to surge if rest periods are short and work levels are high and was also increased by training in the early morning when cortisol levels are naturally higher and the response to exercise can be more. So, It is possible to enjoy the undeniable benefits of exercise while minimising the impact on cortisol concentrations: * Don’t overdo it. Take regular breaks from intense training and listen to your body. * Leave intense sessions to later in the day, when cortisol levels are lower. * Eat right to fuel your body and make sure you consume carbohydrates and protein after exercise to decrease the cortisol response. Remeber, overdoing it can have the opposite effect of what you’re trying to achieve. Therefore, aim for around 150–200 minutes of moderate-intensity exercise each week and allow yourself time to rest between workouts. So that means We are looking at 3 days a week for about :45 minutes total each day. You could add another day of just HIIT intervals on your favorite Cardio Machine. But remember more isn’t always better. #stressbodytype #stresshormone #bodyfat #cortisol #insulin #bodytype #exerciseforyourbodytype #diabetes #bellyfat Suggested Equipment for Use: Amazon list: Theraband Resistance Bands (Yellow, Green & Red) https://amzn.to/3lo660v Assisted Pull-up Band (Long Resistance Band). 3/4”. Black https://amzn.to/3J8QCHk SPRI Resistance Loops. https://amzn.to/3CrkAmo Exercise Ball https://amzn.to/3Sb6pGz Bosu Ball https://amzn.to/3mIU3vw SPRI Resistance Bands With Handles (Green) Medium Resistance. https://amzn.to/3UTdbn3 Neoprene Smaller Weights: https://amzn.to/3xVgqQz Disclaimer: This content including advice provides generic information only. It is in no way a substitute for a qualified medical opinion. Always consult a specialist or your own doctor for more information.