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GLP-1s and Weight Loss: It’s Not Just the Medication—It’s the Method What started as a breakthrough for diabetes management quickly revealed something bigger: GLP-1s weren’t just improving insulin sensitivity—they were helping patients lose significant weight. Once the question was asked—“Can we use GLP-1s solely for weight loss?”—the answer was clear: yes, and the results were remarkable. GLP-1s help by: Improving insulin sensitivity (the opposite of insulin resistance) Decreasing glucagon production Enhancing satiety and fullness Stabilizing energy levels But here’s the key: The most profound and lasting results came when patients paired the therapy with lifestyle upgrades—improved diet, consistent exercise, targeted supplementation, and sustainable habits. At Serotonin Centers, we believe GLP-1 therapy works best when it’s part of a comprehensive wellness strategy, not a standalone solution. Looking to take a smarter, more complete approach to weight loss? Visit our website to get started. #GLP1WeightLoss #InsulinSensitivity #MetabolicHealth #LifestyleOptimization #SerotoninCenters Disclaimer: This content is for informational purposes only and is not intended as medical advice. Consult a healthcare provider for personalized guidance.

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https://youtu.be/KFfABn_021s Looking to learn more about WEGOVY and its side effects? This video covers everything you need to know about this medication, including its effects on the body and specific side effects to watch out for. If you're considering starting WEGOVY or are already using it, this information is crucial. Stay tuned as I also address common questions like how long it takes to lose weight on Wegovy, whether it causes hair loss, and the differences between Rybelsus, Ozempic, and Wegovy. By the end of this video, you'll have a better understanding of WEGOVY and be equipped to make informed decisions regarding its use. Let's dive in! #wegovy #semaglutide #weightloss Disclaimer: The videos posted will be for general informational purposes only. They should not be used to self-diagnose or a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. You should not make any changes to your health regimen or diet before first consulting a doctor.

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While looking over the research on the effect of GLP-1 receptor agonists on alcohol consumption, I stumbled across a recent and _really_ interesting paper on how that class of drugs affects sensation. It's "Glp-1 Receptor Agonists Significantly Impair Taste Function" by Rafa Khan and Richard L. Doty in _Physiology & Behavior_ Vol. 291 (published version at https://www.sciencedirect.com/science/article/abs/pii/S003193842400341X and white paper version at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4953499 ). Don't necessarily take that title on its face, as the details are super important and incredibly interesting and maybe not as dire as you'd think. And, well, I felt like it would be a good use of my platform to discuss all of this. So that's what we're doing today, talking about this hugely consequential new class of drugs - Wegovy/Ozempic (semaglutide), Mounjaro (tirzepatide, although that's also a GIP), and whatever else is going to be out there - with an eye towards spirits nerdery. First I broadly discuss the history and basic mechanisms of these drugs, with a brief detour into side effects and what I would consider to be "best practices" in using them for weight loss purposes. (N.b., I don't get into treatment for type 2 diabetes and that's another set of concerns, also I am not a doctor and please consult a medical professional for all this etc..) And then I discuss the paper above. And... well, it's complicated. Based on their results I think the main takeaway is that while GLP-1 agonists seem to have very good odds of degrading your sense of taste, there's also pretty good odds that you won't actually notice. 🤷 Extra special thanks to my Different Spirits on Patreon (https://www.patreon.com/differentspirits), who got this video first - Eric Amig Anthony Darcy Bean Jamie Brown Kingsbury bushcraft William Christopher Clematis Rob D Liam Davitt Joe Devine Samuel Dose Stephen Eckert eon Ingmar nine Steve Frazee Ian Gendler Solomon Grundy John Halliday Alex Hurd Trevor Jarrait Jonathan Lestingi Kyaru Ariel Mserious Craig Nielsen Jason Newquist No Thanks Chris Rhodes Randy Rice RumSquirrel Gordon W Zach W