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How do I stop gaining weight after stopping Mounjaro or Ozempic? - Dr. Sue Decotiis on Pix11 News Mounjaro have been game changers for people with diabetes and obesity. But once the weight off, is it gone for good? Now, in an Eli Lilly study, when patients stopped taking medication like Mounjaro after 36 weeks, most regained about 14% of their body weight. Other findings were somewhat similar for Ozempic, where two thirds of the total weight loss was then regained. Now some are calling this the Ozempic rebound. So joining us now to talk about it is weight loss expert doctor Sue Decotiis. Welcome to the show. Thank you so much. Okay doctor I feel like everyone is talking about this weight loss journey for a lot of people. First of all, tell us, do you prescribe or recommend this for people and have you seen similar results with the weight coming back? Well, I practice here in Manhattan and my patients are pretty tough. You know, they don't want to regain that weight. As you know, this medication is very expensive. Okay. So what we do is we follow patients very carefully and we put them on a body composition scale every week, every other week. And we make sure they're actually losing fat. Okay. And their muscle is staying the same. They're drinking a lot of water. And we find that after we reach their ideal goal weight, I mean, body fat, not just total weight, okay. That's really important. Most of the doctors prescribing this medication are not even putting people on a body composition scale. And a lot of the studies done by Lilly and Novo Nordisk did not even include a body comp scale. It sounds like rather than just prescribing this medication, you also look at lifestyle changes. Exactly. We do. People, but. We watch that body fat, you know, because a lot of us are heavy, not because we overeat. Our metabolism slows down. Right. So that's what this drug does. It turns insulin on. The other issue that we have is there are a lot of shortages. I mean, I see patients in Connecticut, new Jersey, New York, they come in to see me all over the country. There are shortages all over the place. What the worst thing someone can do is stop the drug abruptly. Okay, so with my patients, I titrate the drug up and I taper it down. That makes such a difference. There's also something called. Touching base on that. How long is someone typically on these drugs? Because it sounds like you start them at one level and you kind of really depends on their metabolism. Exactly. So if I'm following your body composition scale, I'm seeing what's happening with your body fat as I'm taking the drug down. And when I do that, I'll see how well your body is holding. Some people can get off it pretty easily. Okay. We also know now that estrogen is really a positive modulator. See, this is where we're ahead, right? Most of the time women, we have trouble losing weight. We can't compete with men. Right. Estrogen tends to be a modulator for this drug. So women do very very well on this medication. So it really depends on the individual. But when we're monitoring you it's really important that we take you down okay. So if someone is coming off of the medication what other lifestyle changes or what do you suggest that they implement into their life to make sure that they're keeping. Well, if they haven't been? And many of my patients are, they do have a good lifestyle. But we encourage exercise. We don't encourage heavy aerobics, but we want them to build muscle. We want them to eat a lot of protein and vegetables. We measure the fiber in their diet. But again, if insulin isn't working, you can eat really, really well. And my patients are not the type of people that are just watching at home, watching TV and eating Oreos, right? These people are very active. So and these drugs like Mounjaro, Tirzepatide, ozempic, Semaglutide, they really have to be monitored very carefully. And my practice, for the most part, I love to use Tirzepatide. Are there any differences in the medication? There really. Are. So Manjaro is the newer drug okay. And that works by affecting two areas in the stomach, something called GIP as well as GIP one. In my practice, people have lost a lot more weight on Manjaro and Tirzepatide than they did on Ozempic, so that's pretty much my go to drug. There are also less side effects, and I feel that people are more easily tapered off that drug. And the Lilly studies have shown that people lost a lot more body fat on Mounjaro than they did in Ozempic, so realized it's not how much weight you lose. What's your body fat? That's really key, and most people are not getting that advice. Sue Decotiis, MD 20 E 46th St., #1201 New York, NY 10017 Phone: (917) 261-3177 www.drdecotiis.com/ozempic-semaglutide-mounjaro-tirzepatide-weight-loss-doctor-manhattan-nyc pix11.com #Ozempic #Mounjaro #Wegovy #Semaglutide #WeightLoss #weightlossnyc #WeightLossPrescriptions #MedicalWeightLoss #WeightLossDoctor #NYC #DR #MD #News #Pix11

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👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON! https://www.patreon.com/speedpharmacology Antidiabetic drugs are medications used to treat diabetes mellitus by lowering blood glucose levels. With the exception of insulin, exenatide, liraglutide and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents. This pharmacology lecture covers topics such as pathophysiology of diabetes mellitus type 1 & type 2, hyperglycemia, hypoglycemia, insulin production, pancreatic beta & alpha cells, glycogen, glucagon, glucose function; mechanism of action of glucose-lowering drugs; rapid, short, intermediate, long -acting insulin analogs, synthetic amylin, incretin mimetics, DPP-4 inhibitors, sulfonylureas, glinides, biguanides, thiazolidinediones, sodium-glucose cotransporter-2 inhibitors, and alpha-glucosidase inhibitors. Drugs mentioned include insulins Lispro, Aspart, Glulisine, Regular, NPH (isophane), Detemir, Glargine, Degludec; Pramlintide; Exenatide, Liraglutide; Alogliptin, Linagliptin, Saxagliptin, Sitagliptin; Glimepiride, Glyburide, Glipizide; Nateglinide, Repaglinide; Metformin; Pioglitazone, Rosiglitazone; Canagliflozin, Dapagliflozin; Acarbose, and Miglitol. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Diabetes review 2:19 Insulin Analogs 6:40 Synthetic Amylin 7:27 Incretin Mimetics 9:10 DPP4 Inhibitors 9:57 Sulfonylureas 11:49 Glinides 12:36 Biguanides 13:37 Thiazolidinediones 15:30 SGLT2 Inhibitors 16:24 Alpha-glucosidase Inhibitors

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