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Supplements can be valuable part of someone’s health regimen, but it’s also SO important to understand how those supplements may interact with other things you may be taking or what medical tests you may be getting. CONNECT WITH ME: Instagram: https://www.instagram.com/drsamanthaellis/ TikTok: https://www.tiktok.com/@drsamanthaellis Website: https://www.mybeautymd.com/ DISCLAIMER: The information in this video is not intended as medical advice, diagnosis, or treatment. Always seek the advice of your physician. Some of the links in this description may be affiliate links (marked with *). Affiliate links help support my YouTube channel so I can continue to create educational skincare videos for you. Also, some products may have been received as PR. Thanks for watching!

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It's Episode 3, and I'm talkin' about WORKING OUT! It's all about the exercise, and this week, I lost 5.5 pounds! YAY! Don't forget to RATE MY VIDEO!

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Going vegan or vegetarian while using Retatrutide? You can lose fat and build muscle—if you do it the right way. This video breaks down how to get enough protein, fiber, and balance on a plant-based diet that works with your GLP-1 medication. https://kidneypeptides.com/product/retatrutide-20mg-vial/

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Click Here to Subscribe: http://Bit.ly/ThomasVid Website: http://ThomasDeLauer.com Massive Discount on Locally Sourced Grassfed Beef Right to Your Door: https://www.farmfoodsmarket.com/discount/THOMAS2018 How Fasting Burns Fat: Activate Fat Burning Enzymes- Thomas DeLauer… Norepinephrine and Epinephrine: Adrenaline is released from the adrenal cortex & goes through the bloodstream to affect numerous tissues in the body. Noradrenaline is released from the nerve terminals and is the main neurotransmitter of the sympathetic nerves in the cardiovascular system. These two play a primary role in the breakdown of fat by binding to the beta-1 and 2 receptors in the body, which increases cAMP levels which in turn increases fat breakdown. The nervous system sends norepinephrine to the fat cells, making them break down body fat into free fatty acids that can be burned for energy (1,2) Hormone Sensitive Lipase: Fasting increases the activation of hormone sensitive lipase Activating hormone sensitive lipase initiates lipolysis, the breaking down of triacylglycerols into free fatty acids and glycerol (3) Glucagon: Fasting also increases glucagon levels, which breaks down fat - glucagon is a hormone that acts directly opposite to insulin (the pancreas secretes it in an effort to raise blood sugar levels) While insulin stores carbs and builds fat, glucagon is responsible for breaking down stored carbs and fats and releasing them so your body can use them for energy (4) How They All Work Together: The only site for regulation of fatty acid oxidation is at the level of hormone-sensitive lipase in adipose tissue. Under fasting conditions, with minimal insulin in the blood, glucagon promotes formation of the active form of hormone-sensitive lipase. When epinephrine is present, it further actives hormone-sensitive lipase, increasing the hydrolysis of triglycerides to produce free fatty acids (FFA) and glycerol. The glycerol is carried to the liver, where it enters gluconeogenesis, while the FFA are carried on serum albumin to the tissues where they are catabolized for energy. The liver uses some of the energy from fat mobilization to support gluconeogenesis (5) Additional: Ketone Production: Burn Fat Instead of Sugar- Fasting shifts your metabolism from burning sugar to burning fat - begins to break down triglycerides in the form of ketones. References: 1) Zauner C , et al. (n.d.). Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/10837292 2) Jensen MD , et al. (n.d.). Lipolysis during fasting. Decreased suppression by insulin and increased stimulation by epinephrine. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/3540009 3) Sztalryd C and Kraemer FB. (n.d.). Regulation of hormone-sensitive lipase during fasting. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/8141275 4) Marliss EB , et al. (n.d.). Glucagon levels and metabolic effects in fasting man. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/5480852 5) Hormone-sensitive lipase - an overview | ScienceDirect Topics. (n.d.). Retrieved from https://www.sciencedirect.com/topics/neuroscience/hormone-sensitive-lipase 6) Adrenalin and Noradrenalin The 'Dynamic Duo? (2015, April 9). Retrieved from https://thefatlossmanifesto.com/adrenalin-and-noradrenalin-the-dynamic-duo/

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In this episode of the Find Your Food Voice podcast, Julie Duffy Dillon, along with guests Coleen Bremner and Rachel Popik, discuss predicted wellness trends for 2025. They explore the evolving narratives around diet culture, the stigmatization of processed foods, the rise of hormone balancing as a wellness trend, and the implications of GLP-1 medications in weight loss discussions. The conversation emphasizes the importance of community support in navigating these trends and encourages critical consumption of media related to diet culture. Takeaways The Find Your Food Voice book is now available for pre-order. There is a noticeable shift in diet culture narratives towards more explicit weight loss discussions. Community support is crucial in resisting diet culture pressures. Processed foods are being stigmatized despite their nutritional value and convenience. Hormone balancing is becoming a catch-all phrase in wellness trends without clear definitions. GLP-1 medications are being marketed heavily, creating a complex narrative around weight loss. Shame is a common theme in diet culture and should be critically examined. Media consumption should be approached with a critical mindset to avoid harmful narratives. The importance of recognizing the dehumanization of bodies in diet culture discussions. Engagement with community can provide support and resilience against diet culture.

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