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Which GLP 1 Is Best For Cardiovascular Benefit? In this informative video, we’ll discuss the various GLP-1 receptor agonists and their potential cardiovascular benefits. Understanding these medications is essential for managing type 2 diabetes effectively, especially when considering their impact on heart health. We will explore how these drugs mimic natural hormones in the body to regulate blood sugar levels while also influencing cardiovascular risk factors. We’ll cover the differences among GLP-1 RAs and their specific effects on heart failure and major adverse cardiovascular events (MACE). You’ll learn about the results from key studies and how they relate to the effectiveness of different agents. Additionally, we’ll highlight how GLP-1 RAs can aid in weight loss and improve blood pressure and lipid profiles. Choosing the right medication is crucial, and we’ll discuss factors to consider when selecting between GLP-1 RAs and SGLT2 inhibitors based on individual patient needs. This video aims to provide you with a clearer understanding of which GLP-1 receptor agonist may offer the best cardiovascular protection for you or your loved ones. Join us for this informative discussion, and don't forget to subscribe to our channel for more helpful information on cardiology and diabetes management. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@CardiologyCommunity/?sub_confirmation=1 #Cardiology #GLP1 #DiabetesManagement #HeartHealth #CardiovascularBenefits #HeartFailure #MACE #WeightLoss #BloodPressure #Cholesterol #SGLT2Inhibitors #MedicationChoices #HealthInformation #DiabetesAwareness #CardiovascularRisk About Us: Welcome to Cardiology Community, your trusted source for all things related to cardiology and heart health. Our mission is to provide engaging, informative content that helps you understand the complexities of cardiovascular wellness. Please note that our content is purely informational and should not be considered medical advice. Always consult with a healthcare professional for personal health concerns and do your own research to make informed decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

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"Why am I not losing fat even though my calorie intake is very low?" Here's the scientific answer and what to do about it! Subscribe here https://www.youtube.com/subscription_center?add_user=shockingfit Online Coaching now available: https://www.tomic.com/contact/ The necessary calorie intake for fat loss can vary greatly among individuals. A typical "bulk" intake of 3000-3500 calories for some people might be causing fat loss or weight maintenance. And that same person who has to go high on calories to gain weight might need to go very low on calories to lose weight. In general, we know that the energy balance equation holds. If you're in a caloric deficit, you will lose weight. But some people adapt much better to a low-calorie diet and their body reduces the amount of energy expended to compensate for the lowered intake. In the bodybuilding/fitness world this is called having an "adaptive metabolism." There are four main components of the "Calories Out" portion of the energy balance equation: Basal metabolic rate (BMR) Thermic Effect of Food (TEF) Physical Activity (PA) Non-exercise activity thermogenesis (NEAT) Let's look at all four of these to see how they would adapt to a lower calorie intake on a fat loss diet. BMR - It will naturally reduce as you weight goes down, but it doesn't change many people to the person with the same stats. It's pretty consistent with 96% of the population is in the range of 1680-2320 kcal/day. TEF - The energy expenditure from thermic effect is about 10% of your total calorie intake. https://ajcn.nutrition.org/content/63/2/164.abstract PA - As you lower your body weight you'll burn a bit fewer calories from your deliberate physical activity. NEAT - Now, this is where there are massive variations between individuals. Some people will adapt very well to overfeeding and underfeeding through regulating their NEAT levels while others will have a more rigid response. One of the main reasons for the differences in NEAT is genetics. If we look at a fascinating study back from 1990 by Dr. Claude Bouchard: https://www.nejm.org/doi/full/10.1056/NEJM199005243222101#t=article We can see to which extent genetics can play a huge role in fat gain and distribution of fat. In the study, they took 12 pairs of identical twins. The participants were male with average age of 21. First off they determined how many calories each person needed to eat to maintain weight, then the researchers overfed each by 1000 kcal/day for 84 days. Every participant of the study gained fat but what's fascinating are the large differences between the pairs of twins. Within the pairs, there wasn't much difference. But between the pairs the weight gain ranged from 9 pounds (4.3 kg) to 29 lbs (13 kg) despite the fact that all subjects had the same calorie surplus. Some pairs were just able to effortlessly "burn off" the excess calories. And not only did pairs differ in weight gain but also in the distribution of body fat increased. This marker as well was quite similar between the twins. i.e. if one twin gained 15 lbs around the midsection, the other usually gained about the same amount of weight in the same place. As you can see genetics do play a role, and some people are more "resistant" to overfeeding. Another interesting finding from this study is that some people will have an easier time showing their six pack due to less of their fat stored in the midsection. The research on NEAT: https://www.sciencemag.org/content/283/5399/212.short https://www.ncbi.nlm.nih.gov/pubmed/12468415 Further reading: https://wholehealthsource.blogspot.com/2013/06/the-genetics-of-obesity-part-i.html Check out these videos: How to estimate your calorie intake https://www.youtube.com/watch?v=Y8nKEwrN9I0 For calculating your macros https://www.youtube.com/watch?v=VIFRY_--YuU Why do some people never get fat https://www.youtube.com/watch?v=5nO9-nbeUIk The slow/fast metabolism myth https://www.youtube.com/watch?v=bO44Q3XGuvM Further reading: https://www.bodyrecomposition.com/fat-loss/the-energy-balance-equation.html https://www.nejm.org/doi/full/10.1056/NEJM199005243222101#t=article Talk soon, Mario Online Coaching: https://www.tomic.com/contact/ For more fitness, nutrition, and personal development tips check out: Facebook: https://www.facebook.com/MarioTomicOfficial Instagram: https://instagram.com/mariotomich Website: https://www.tomic.com Music: Falling Down by Ryan Little https://freemusicarchive.org/music/Ryan_Little/Before_Dawn_Instrumental_Album/01_Falling_Out_prod_by_R4C2010 Follow Ryan Little at: https://www.youtube.com/TheR4C2010

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