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GLP-1 agonists are used to treat diabetes type 2 and obesity. They work by increasing insulin release and reducing appetite. There are a number of different GLP-1 medications available. If you’ve been taking a compounded GLP-1, you may need to switch to a branded option. Learn your options in this video, according to Stacia Woodcock, PharmD, Pharmacy Editor at GoodRx. Learn more: https://goodrx.co/GLP1Drugs Go to https://goodrx.co/health for the answers you need from doctors, pharmacists, and journalists you can trust. Follow Us On Social: TikTok - https://goodrx.co/TikTok Instagram - https://goodrx.co/instagram Facebook - https://goodrx.co/Facebook X - https://x.com/GoodRx #glp1 #semaglutide #tirzepatide
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Obesity is a prevalent issue in today’s society, affecting millions of individuals worldwide. It is often linked to various health complications such as diabetes, heart disease, and stroke. Many people struggle with achieving and maintaining a healthy weight, leading them to explore different options for weight loss. One such option is the drug Semaglutide, which has been gaining attention for its potential effects on weight reduction.
Evaluating the Efficacy of Semaglutide
Semaglutide is a medication that has traditionally been used to treat type 2 diabetes. However, recent studies have shown that it may also be beneficial in promoting weight loss. The drug works by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and appetite. By stimulating the release of insulin and slowing down gastric emptying, Semaglutide can lead to decreased appetite and calorie intake.
One recent clinical trial, known as the STEP 1 study, investigated the impact of Semaglutide on weight loss in individuals with obesity. The results were promising, with participants who took Semaglutide experiencing a significant decrease in body weight compared to those who received a placebo. On average, participants lost around 15% of their body weight while taking the drug, demonstrating its effectiveness as a weight loss aid.
Potential Side Effects of Semaglutide
Although Semaglutide shows promise as a weight loss treatment, it is essential to consider the potential side effects associated with the medication. Some common side effects reported in clinical trials include nausea, vomiting, diarrhea, and constipation. These gastrointestinal symptoms are often transient and tend to improve over time as the body adjusts to the drug.
In rare cases, more serious side effects may occur, such as pancreatitis or gallbladder disease. It is crucial for individuals considering Semaglutide for weight loss to consult with their healthcare provider to discuss the potential risks and benefits. Monitoring for any signs of adverse effects is essential to ensure the safe use of the medication.

Incorporating Semaglutide into a Weight Loss Plan
For individuals looking to incorporate Semaglutide into their weight loss journey, it is essential to do so under the guidance of a healthcare professional. The medication is typically prescribed in conjunction with a healthy diet and exercise regimen to maximize its effects. It is not a standalone solution but rather a tool to support sustainable weight loss efforts.
Additionally, behavioral changes such as mindfulness practices, stress management, and adequate sleep play a crucial role in achieving long-term weight loss success. Semaglutide should be viewed as part of a comprehensive approach to health and wellness, rather than a quick fix solution.
Future Research and Considerations
As research on Semaglutide and its effects on weight loss continues to evolve, it is essential to stay informed about the latest findings and developments. Long-term studies are needed to assess the sustainability and safety of using Semaglutide for weight management. Additionally, efforts to address disparities in access to weight loss medications and comprehensive care are crucial to support individuals in achieving and maintaining a healthy weight.
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00:00 - The Truth About GLP-1 Drugs: Weight Loss and Muscle Loss Explained 04:23 - Lose Weight Naturally: No Expensive Injectables Needed! 09:13 - GLP-1 Weight Loss: The Essential Diet & Exercise Guide for Long-Term Success 1. The Truth About GLP-1 Drugs: Weight Loss and Muscle Loss Explained In this video, we explore the recent findings on GLP-1 drugs and their impact on weight loss and muscle mass. While these medications can help individuals lose significant weight, they may not improve heart and lung function as expected. We discuss the importance of exercise and nutrition in conjunction with GLP-1 therapy to ensure overall health and well-being. Learn about the potential risks of muscle loss and how to mitigate them with proper strategies. Join us for an insightful discussion on maintaining cardiorespiratory fitness while using GLP-1 drugs. 2. Lose Weight Naturally: No Expensive Injectables Needed! Discover how to lose weight without expensive injectables like Wegovy, Ozempic, and Zepbound. Dr. Marcie Fraser shares practical tips for sustainable weight loss through lifestyle changes, including calorie awareness, portion control, meal prep, strength training, and cardio exercises. Learn about Dr. Fraser’s Forever Fit program designed for women over 40 to reclaim their strength and confidence. Start your wellness journey today! 3. GLP-1 Weight Loss: The Essential Diet & Exercise Guide for Long-Term Success Discover how GLP-1 medications like Wegovy and Ozempic work best when combined with personalized nutrition and exercise plans. Harvard expert Dr. JoAnn Manson reveals: ✅ Why muscle mass loss is common with GLP-1s ✅ The 3-step physical activity plan for optimal results ✅ How to track weight loss safely and avoid excessive weight loss ✅ Protein intake guidelines (60-75g/day) to preserve lean mass ✅ Managing side effects: nausea, constipation, reflux ✅ Long-term strategies to prevent weight regain after stopping GLP-1s This video breaks down key clinical insights from JAMA Internal Medicine on integrating GLP-1 therapy with lifestyle changes. Learn how to balance nutrient-dense meals, structured exercise routines, and regular monitoring for sustainable weight management. Includes practical tips for doctors and patients on dose titration, micronutrient monitoring, and creating maintenance protocols. Whether you're starting GLP-1 therapy or looking to enhance your weight loss journey, this guide covers everything from initial dose escalation to long-term maintenance strategies. Don't miss the expert recommendations on resistance training, appetite management, and preventing metabolic relapse.