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😲Game Changer ของโรคอ้วน!! ใครเล่นหุ้นต้องจับตาดูสองบริษัทนี้ดีๆ GLP-1 ซึ่งเป็นฮอร์โมนช่วยสั่งสมองให้ลดความอยากอาหาร พัฒนาเป็นยาลดความอ้วน ยาตัวแรกมาด้วยชื่อ Saxenda จาก Novo Nordisk เริ่มใช้ตั้งแต่ 2014 ลดน้ำหนักได้สูงสุด 5% ของน้ำหนักตัว พัฒนาต่อมาเป็น Wegovy จาก Novo อีกเช่นเคย ในปี 2021 เป็น "GAME CHANGER" เลยเพราะลดน้ำหนักได้สูงสุด 15%! แต่ที่พีคกว่านั้นคือสิงหาปีที่แล้ว 2023 Eli Lilly ปล่อยยาตัวใหม่ชื่อ Zepbound เป็น Dual action ทั้ง GLP-1 และ GIP ฮอร์โมนอีกตัวนึง น้อง Zepbound ลดน้ำหนักได้สูงสุด 21%!! ตัวนี้ทำตลาดอเมริกาแตก ทั้งตลาดยาและตลาดหุ้น! อนาคตตลาดยาคาดว่าจะโตปีละ 4% และมาจับตาดูยากินจาก Eli Lilly กันค่ะ !! อ้างอิงจาก: https://www.biochempeg.com/article/332.html https://www.nejm.org/doi/full/10.1056/NEJMoa2206038 https://www.nytimes.com/2023/08/17/health/weight-loss-drugs-obesity-ozempic-wegovy.html https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2019.00155/full https://www.reuters.com/business/healthcare-pharmaceuticals/eli-lilly-beats-profit-estimates-diabetes-weight-loss-drug-strength-2024-04-30/ https://money.usnews.com/investing/articles/diabetes-and-weight-loss-drug-stocks-with-big-potential https://www.fiercebiotech.com/biotech/pfizer-plans-be-very-active-obesity-market-ceo-mum-precise-rd-plans?utm_medium=email&utm_source=nl&utm_campaign=LS-NL-FiercePharma+Tracker&oly_enc_id=4902C2464678I2I https://investor.lilly.com/news-releases/news-release-details/lilly-present-new-research-treatment-diabetes-and-obesity https://pubmed.ncbi.nlm.nih.gov/36050763/ https://www.iqvia.com/blogs/2024/02/2024-the-obesity-markets-inflection-point#:~:text=Global%20obesity%20spending%20reached%20nearly,by%202028%2C%20according%20to%20the https://web.musc.edu/about/news-center/2023/11/13/fda-approves-new-weight-loss-drug-with-remarkable-track-record https://hitconsultant.net/2023/11/06/prescribing-trends-surge-wegovy-ozempic-gain-popularity/ https://www.fastcompany.com/91108767/zepbound-shortage-2024-update-limited-availability-when-end-date https://www.everydayhealth.com/weight/an-expert-q-a-on-zepbound-tirzepatide-the-mounjaro-offshoot-newly-approved-as-a-weight-loss-drug/ #biotechnology #glp1 #obesity #wegovy #zepbound #novonordisk #elililly #pfizer #stocks #ลดความอ้วน #ตลาดหุ้น #usa #อเมริกา #weightloss #ลดน้ำหนัก 00:00 Highlights 00:14 Intro 01:42 ปัญหาโรคอ้วนในอเมริกา 02:26 ตลาดยาลดความอ้วน 03:07 ทำไม GLP-1 ถึงใช้ลดน้ำหนักได้ 04:26 ยา GLP-1 จาก Novo Nordisk 06:15 ยา GLP-1 จาก Eli Lilly 07:58 อนาคตยาลดความอ้วน 09:23 ข้อควรระวังในการใช้ 10:55 ผลหลังหยุดยา
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Semaglutide is a medication that has been making waves in the weight loss industry for its effectiveness in helping people shed excess pounds. Originally developed as a treatment for type 2 diabetes, semaglutide has shown promising results in clinical trials for weight management, leading to its approval by the FDA for this purpose. If you’ve been struggling to lose weight through diet and exercise alone, semaglutide tablets may be a game-changer for you.
What is Semaglutide?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it works by mimicking the effects of the natural hormone GLP-1 in the body. GLP-1 is responsible for regulating blood sugar levels, appetite, and body weight. By activating GLP-1 receptors in the brain, semaglutide can help reduce hunger and increase feelings of fullness, making it easier to stick to a calorie-controlled diet and lose weight.
In addition to its effects on appetite and weight loss, semaglutide also improves insulin sensitivity and glucose metabolism, making it an effective option for people with type 2 diabetes who are overweight or obese. This dual benefit makes semaglutide a valuable tool in the management of both conditions.
Semaglutide is available in tablet form for once-daily dosing, which is convenient for many people compared to injections or other weight loss medications that require more frequent administration. The tablets are typically taken in the morning on an empty stomach, with or without food, depending on the individual. It’s important to follow your healthcare provider’s instructions on how to take semaglutide to ensure maximum effectiveness.
How Does Semaglutide Work for Weight Loss?
When you take semaglutide, it activates GLP-1 receptors in the brain, which signal to your body that you are full and satisfied. This reduces your appetite and cravings for high-calorie foods, making it easier to stick to a healthy eating plan and consume fewer calories overall. By creating a calorie deficit, your body starts burning stored fat for energy, leading to weight loss over time.
In addition to its effects on appetite, semaglutide also slows down gastric emptying, meaning food stays in your stomach longer and you feel fuller for longer periods after eating. This helps prevent overeating and snacking between meals, further supporting weight loss efforts. The combination of reduced hunger and delayed stomach emptying makes semaglutide a powerful tool for long-term weight management.
Studies have shown that semaglutide can help people lose significant amounts of weight when used as part of a comprehensive weight loss program that includes diet and exercise. In one clinical trial, participants who took semaglutide lost an average of 15% of their body weight over 68 weeks, compared to 2.4% in the placebo group. These results demonstrate the efficacy of semaglutide in aiding weight loss when used consistently and as directed.
What Are the Benefits of Using Semaglutide for Weight Loss?
One of the main benefits of using semaglutide for weight loss is its ability to reduce appetite and increase feelings of fullness, making it easier to control portion sizes and food cravings. This can lead to a sustainable weight loss journey that doesn’t feel overly restrictive or challenging. By taking semaglutide, you may find it easier to make healthier food choices and stick to your weight loss goals in the long run.
Another benefit of semaglutide is its effect on metabolic health, including improved insulin sensitivity and glucose control. People with type 2 diabetes may see additional benefits from taking semaglutide, as it can help lower blood sugar levels and reduce the risk of complications associated with uncontrolled diabetes. By addressing both weight management and diabetes management, semaglutide offers a comprehensive approach to improving overall health.
Additionally, semaglutide has been shown to have positive effects on cardiovascular health, including reducing the risk of heart disease and stroke in people with obesity and diabetes. By promoting weight loss and improving metabolic markers, semaglutide can help lower the risk of chronic diseases that are often linked to excess weight. This holistic approach to health makes semaglutide a valuable tool for people looking to improve their overall well-being.
Are There Any Side Effects or Risks Associated with Semaglutide?
Like any medication, semaglutide comes with potential side effects and risks that you should be aware of before starting treatment. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation, which may improve over time as your body adjusts to the medication. It’s important to stay hydrated and eat small, frequent meals to help manage these gastrointestinal symptoms.
In rare cases, semaglutide can cause more serious side effects, such as pancreatitis, gallbladder problems, kidney problems, or low blood sugar (hypoglycemia), especially when used in combination with other diabetes medications. If you experience severe abdominal pain, persistent vomiting, or changes in urination or blood sugar levels while taking semaglutide, seek medical attention immediately.
People with a history of pancreatitis, gallstones, kidney disease, or thyroid disorders may be at higher risk of experiencing complications with semaglutide and should discuss their medical history with their healthcare provider before starting treatment. Semaglutide is not recommended for use in pregnant women or people with a history of medullary thyroid carcinoma (a type of thyroid cancer).
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Don’t forget to like, subscribe, and hit the bell icon for more insights on fitness and performance enhancers! Follow Me: Instagram (Main): tony.huge Instagram: superhuman.ceo Tiktok: superhumanceo Facebook: superhumanceo DISCLAIMER: The Video Content is not intended to substitute professional medical advice, diagnosis, or treatment. Always seek your physician's advice or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.
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Ozempic vs. Mounjaro: Weight Loss Medications – Blessing or Threat? In this video, we dive deep into the buzz surrounding Ozempic and Mounjaro, two groundbreaking medications initially designed to treat type 2 diabetes but now making waves in the world of weight loss. Are these injectable medications the miracle solutions everyone’s been waiting for, or do they pose serious risks that outweigh the benefits? Topics Covered: - How Ozempic (semaglutide) and Mounjaro (tirzepatide) work in the body - Pros and cons of using these medications for weight loss - Potential side effects and long-term health concerns - Are they safe for non-diabetic users? - Real stories: Transformations, triumphs, and warnings Key Question: Should we celebrate these medications as a blessing for millions struggling with obesity, or do we need to sound the alarm on potential misuse and health risks? 💡 Whether you’re considering these options, know someone who is, or just want to stay informed, this video breaks down the science, the hype, and the controversy behind Ozempic and Mounjaro. 📌 **Disclaimer:** This video is for informational purposes only. Please consult a healthcare professional for medical advice tailored to your needs. #Ozempic #Mounjaro #WeightLoss #HealthDebate #DiabetesMedication #WeightLossJourney #HealthTips
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