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I cover 8 ESSENTIAL things you need to know BEFORE STARTING GLP1 medications like semaglutide or tirzepatide (Ozempic/Mounjaro) for weight loss without watching this first! I'm Dr G., an internal medicine physician in Hollywood Florida, and I specialize in lifestyle modification coaching and patient education. FREE TDEE Calculator👉https://www.fcmaesthetics.com/tdee 1:1 Consultation with Dr. G👉https://www.floridaconciergemed.com/ GLP-1 Meal Plan Delivery👉https://trifectanutrition.llbyf9.net/9g4vXe Use Code "DRGLP1" for 40% OFF Your First Order! Dr. Gerard Acloque Jr., MD Hollywood, FL #weightloss #glp1 #glp1forweightloss #semaglutide #tirzepatide Some of the links in this description are affiliate links, which means I may earn a small commission if you make a purchase through them, at no extra cost to you. References 1. Wilding, J. P., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Lau, D. C. (2021). Once-weekly semaglutide in adults with overweight or obesity. *New England Journal of Medicine*, 384(11), 989-1002. 2. Wadden, T. A., Bailey, T. S., Billings, L. K., Davies, M., Frias, J. P., Koroleva, A., ... & Lingvay, I. (2019). Effect of subcutaneous semaglutide on body weight in patients with obesity: The STEP 1 randomized clinical trial. *Obesity Reviews*, 20(12), 1997-2018. 3. Davies, M. J., Bergenstal, R., Bode, B., Kushner, R. F., Lewin, A., Skjøth, T. V., ... & Pedersen, S. D. (2015). Efficacy of liraglutide for weight loss among patients with type 2 diabetes: The SCALE diabetes randomized clinical trial. *JAMA*, 314(7), 687-699. 4. Holst, J. J. (2019). The physiology of glucagon-like peptide 1. *Physiological Reviews*, 97(2), 725-738. 5. Kushner, R. F., & Kahan, S. (2018). Introduction: The state of obesity in 2018. *Medical Clinics*, 102(1), 1-11. 6. Ryan, D. H., Lingvay, I., Colhoun, H. M., Deanfield, J., García-Pérez, L. E., Jodar, E., ... & Cosentino, F. (2021). Role of obesity in cardiovascular disease. *European Heart Journal Supplements*, 23(Supplement B), B45-B54. 7. Rubino, D., Abrahamsson, N., Davies, M., Hesse, D., Greenway, F. L., Jensen, C., ... & Van Gaal, L. (2021). Effect of continued weekly subcutaneous semaglutide on weight loss in adults with obesity: The STEP 1 trial extension. *The Lancet*, 397(10277), 2146-2155. This channel (Florida Concierge Medicine & Wellness/Dr. Gerard Acloque), its content, and the opinions expressed by Dr. G are intended for informational purposes only and do not constitute medical advice. The content provided on this channel, including videos, comments, and other materials, is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified and trusted health provider with any questions you may have regarding any medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or read on this channel. Reliance on any information provided by this channel is solely at your own risk.
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Obesity is a significant health concern that affects millions of people worldwide. With the prevalence of this condition on the rise, researchers and healthcare professionals are constantly seeking effective treatments to help individuals achieve and maintain a healthy weight. One promising option that has gained attention in recent years is semaglutide, a medication originally developed for managing type 2 diabetes but has shown remarkable results in promoting weight loss. In this article, we will explore the benefits of semaglutide for effective weight loss.
The Mechanism of Semaglutide for Weight Loss
Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. These medications work by mimicking the effects of a natural hormone called GLP-1, which helps regulate blood sugar levels, appetite, and metabolism. When administered, semaglutide increases the secretion of insulin, slows down gastric emptying, and reduces appetite, leading to decreased food intake and weight loss.
Furthermore, semaglutide has been shown to have a positive impact on other factors related to obesity, such as lowering cholesterol levels, reducing inflammation, and improving insulin sensitivity. These additional benefits make semaglutide a comprehensive treatment option for individuals struggling with excess weight and related health issues.
Studies have demonstrated that semaglutide is highly effective in promoting weight loss in both overweight and obese individuals. In a large clinical trial involving over 2,000 participants with obesity, those who received semaglutide lost an average of 15% of their body weight over the course of 68 weeks, compared to 2.4% in the placebo group. These results highlight the significant potential of semaglutide as a powerful tool for combating obesity.
Potential Side Effects and Considerations
While semaglutide has shown promising results in promoting weight loss, it is essential to consider the potential side effects and risks associated with this medication. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation, which may occur during the initial phase of treatment but tend to improve over time.
It is also important to note that semaglutide is not suitable for everyone, particularly individuals with a history of pancreatitis, thyroid cancer, or severe gastrointestinal disorders. Before starting treatment with semaglutide, individuals should consult with their healthcare provider to determine if this medication is appropriate for their specific health needs and goals.
Furthermore, it is crucial to combine semaglutide treatment with a healthy diet, regular exercise, and lifestyle modifications to maximize the benefits of weight loss. By adopting a holistic approach to weight management, individuals can achieve long-term success in reaching and maintaining a healthy weight.
Future Implications and Research Directions
The success of semaglutide in promoting weight loss has sparked interest in exploring its potential applications in other areas of healthcare, such as the treatment of metabolic disorders, cardiovascular disease, and nonalcoholic fatty liver disease. Researchers are actively investigating the mechanisms of action of semaglutide and its impact on various health outcomes, with the goal of expanding its therapeutic use beyond weight management.
As scientific understanding of semaglutide continues to evolve, new formulations and dosage regimens may be developed to enhance its efficacy and tolerability. Ongoing clinical trials are evaluating the long-term safety and effectiveness of semaglutide in diverse patient populations, providing valuable insights into its role in addressing the global epidemic of obesity and its associated complications.
In conclusion, semaglutide presents a promising treatment option for individuals seeking to achieve meaningful weight loss and improve their overall health. By harnessing the therapeutic potential of this medication and implementing a comprehensive approach to weight management, individuals can overcome the challenges of obesity and embark on a path towards a healthier and more fulfilling life.
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