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All GLP-1 receptor agonists share a common mechanism, activation of the GLP-1 receptor. GLP-1 receptors are expressed by β cells, cells in the peripheral and central nervous systems, the heart and vasculature, kidney, lung, and GI mucosa. Binding of agonists to the GLP-1 receptor activates the cyclic AMP-PKA pathway and several GEFs (guanine nucleotide exchange factors). GLP-1 receptor activation also initiates signaling via PKC and PI3K and alters the activity of several ion channels. In β cells, the end result of these actions is increased insulin biosynthesis and exocytosis in a glucose-dependent manner

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00:00 - Pharmacies Warn of Unsustainable Demand for Weight Loss Medication: What You Need to Know 03:18 - Rising Demand for Weight Loss Drugs: A Growing Concern Among Young Adults 06:42 - UK Pharmacists Warn of Unsustainable Demand for Weight Loss Drugs 1. Pharmacies Warn of Unsustainable Demand for Weight Loss Medication: What You Need to Know The demand for weight loss medications like Wegovy and Mounjaro is skyrocketing, but pharmacists warn that the current trend may be unsustainable. In this video, we delve into the findings of a recent National Pharmacy Association (NPA) poll, which reveals that a significant number of people are interested in weight loss treatments, but many may not be clinically eligible. We discuss the potential risks of unregulated online suppliers and the importance of regulated pharmacies in managing these medications. Learn about the role of pharmacies in the NHS weight management program and how they can help ensure that these powerful medicines are used safely and effectively. Join us as we explore the implications of this growing demand and what it means for public health. 2. Rising Demand for Weight Loss Drugs: A Growing Concern Among Young Adults New polling reveals 35% of 18-34-year-olds have tried to access weight loss medication in the past year, far exceeding the national average. With 64% of 25-34-year-olds willing to use weight loss jabs if free on the NHS, experts warn of a potential supply crisis. Drugs like Wegovy and Mounjaro, historically reserved for medical conditions, are now sought after for aesthetic reasons linked to a resurgence of extreme thinness as a beauty standard. Supply shortages in the UK and warnings from regulators about unregulated online purchases highlight the urgent need for responsible use. This trend raises critical questions about public health, accessibility, and the role of pharmaceutical policies. Key takeaways: Rising demand, aesthetic-driven weight loss, supply chain challenges, and the importance of prescription requirements for safety. 3. UK Pharmacists Warn of Unsustainable Demand for Weight Loss Drugs Pharmacists in the UK are warning that the demand for weight loss drugs is becoming unsustainable, with over a million people using medications like Wegovy and Mounjaro. The National Pharmacy Association has expressed concerns that the supply of these medications may soon be unable to meet the growing demand, leading to potential shortages and encouraging people to turn to unregulated online sources. In this video, we'll discuss the implications of this trend and what it means for those seeking weight loss treatment. The demand for weight loss medications has been driven in part by the success of medications like Wegovy and Mounjaro, which have been shown to be effective in helping people lose weight. However, the high demand for these medications has put a strain on the supply chain, leading to shortages in some parts of the UK. The National Pharmacy Association has warned that the growing demand for weight loss medications is unsustainable and that the supply of these medications may soon be unable to meet the demand. This could lead to potential shortages and encourage people to turn to unregulated online sources, which can be dangerous and ineffective. In this video, we'll discuss the implications of this trend and what it means for those seeking weight loss treatment. We'll also explore the potential solutions to this problem and how pharmacists and healthcare professionals can work together to ensure that those who need weight loss medications can access them safely and effectively. Keywords: weight loss, medications, Wegovy, Mounjaro, National Pharmacy Association, UK, pharmacists, healthcare, weight loss treatment, obesity, health.

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Are you stuck at the same weight for weeks while on Ozempic, Wegovy, Mounjaro, or Zepbound? Wondering if it’s time to increase your GLP-1 dose? In this video, I break down the real signs it’s time to go up—and the major red flags to watch for. We’ll talk food noise, weight plateaus, side effects, and the right way to progress so you don’t end up quitting the meds altogether. Always consult with your healthcare provider! ~Juls My Private Facebook Group - https://www.facebook.com/share/qmphPaBWHcGDXjrq/ My Instagram https://www.instagram.com/julswellnesswarrior Julian Bakery https://julianbakery.com/?sca_ref=8317917.1wBQnkwey2zPhy Coupon Code “SPRING15” 15% OFF Hooga Health https://hoogahealth.com/?ref=JULIANNEROMAN Coupon Code “Juls” 12% OFF Bon Charge https://boncharge.com/?rfsn=8102693.58c6e3 Coupon Code “Juls” 15% OFF

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