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Curious about weight changes after stopping GLP-1 drugs? Let's dive into the evidence on what happens with stopping and how to minimize the risk.
References:
-Xujia Lu et al. Habitual Coffee, Tea and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity. JCEM, 2024 DOI: 10.1210/clinem/dgae552
-Wilding JPH, Batterham RL, Davies M, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022; 24(8): 1553-1564. doi:10.1111/dom.14725
-Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021;325(14):1414–1425. doi:10.1001/jama.2021.3224
-Aronne LJ, et al "Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity" JAMA 2023; DOI: 10.1001/jama.2023.24945.
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Nutritionist Maya Feller discusses what to know about the new findings that some people were able to put their Type 2 diabetes into remission using a rigorous liquid diet instead of medication.
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The Dangers of Off-Brand Ozempic This week on 51-49, James breaks down the controversy surrounding Hims & Hers’ viral Super Bowl ad — an ad that claims to fight Big Pharma while selling its own weight-loss drugs. Behind the marketing, we uncover how Hims & Hers isn’t disrupting the system — they’re exploiting a loophole to become the next Big Pharma giant. From compounded semaglutide risks to the bigger question of corporate control over public health, this is the real story behind the weight-loss drug gold rush. 0:00 The Most ANTI-AMERICAN Super Bowl Ad 2:16 What is Hims & Hers? 3:54 The Dangers of Semaglutide 6:13 Compounded, Off-Label Ozempic?! 7:50 What is the Solution? 51-49 with James Li - Documentaries funded by the people, for the people. Follow James on TikTok: https://www.tiktok.com/@5149jamesli Follow James on X (formerly Twitter): https://twitter.com/5149jamesli Subreddit link: https://www.reddit.com/r/5149withJamesLi/ Merch store: https://www.redbubble.com/people/5149jamesli ----- Meditation 1 by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Clean Soul - Calming by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ ----- Fair Use Notice: This video may contain copyrighted material; the use of which has not been specifically authorized by the copyright owner. We are making such material available for the purposes of criticism, comment, review and news reporting which constitute the fair use of any such copyrighted material as provided for in section 107 of the US Copyright Law. Not withstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work for purposes such as criticism, comment, review and news reporting is not an infringement of copyright.
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Semaglutide tablets for weight loss have been making headlines in the health and wellness industry for their promising results in helping individuals achieve their weight loss goals. This medication, originally developed to treat type 2 diabetes, has shown significant potential in promoting weight loss when used at a higher dose specifically for that purpose.
How Semaglutide Works
Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. These medications work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) that is naturally produced in the body. GLP-1 helps regulate blood sugar levels, decrease appetite, and slow down digestion, which can all contribute to weight loss.
When Semaglutide is taken at a higher dose for weight loss, it helps control appetite, leading to reduced food intake and ultimately weight loss. Additionally, it can help improve insulin sensitivity, reduce inflammation, and increase energy expenditure, all of which can further support weight loss efforts.
Studies have shown that individuals taking Semaglutide for weight loss in addition to making healthy lifestyle changes have experienced significant weight loss compared to those using a placebo. It has been shown to be particularly effective for individuals who are overweight or obese and have struggled to lose weight through diet and exercise alone.
Potential Side Effects
Like any medication, Semaglutide tablets for weight loss can have side effects that individuals should be aware of before starting treatment. Common side effects may include nausea, vomiting, diarrhea, and constipation, especially when starting the medication or increasing the dose.
More serious side effects may include pancreatitis, kidney problems, gallbladder issues, and low blood sugar (hypoglycemia) when used in combination with other blood sugar-lowering medications. It is important for individuals to discuss their medical history and any existing conditions with their healthcare provider before starting Semaglutide for weight loss.
It is also crucial to follow the dosing instructions provided by a healthcare provider and report any side effects or concerns promptly. Some individuals may not be suitable candidates for Semaglutide treatment due to existing health conditions, so a thorough evaluation is necessary before starting this medication for weight loss purposes.
Effectiveness and Long-Term Use
While Semaglutide tablets have shown promising results in promoting weight loss, it is essential to emphasize that this medication is not a quick fix or a standalone solution. Sustainable weight loss requires a holistic approach that includes healthy eating, regular physical activity, and behavior modifications.
Individuals using Semaglutide for weight loss should work closely with their healthcare provider to develop a comprehensive weight loss plan that addresses their individual needs and goals. This may include regular monitoring of weight, blood sugar levels, and any potential side effects to ensure the medication is working effectively and safely.
Long-term use of Semaglutide for weight loss is still being studied, and it is important for individuals to remain under the care of a healthcare provider while taking this medication. Regular check-ups and consultations can help monitor progress, make necessary adjustments to the treatment plan, and address any concerns that may arise during the weight loss journey.
Cost and Accessibility
One of the potential barriers to accessing Semaglutide tablets for weight loss is the cost of the medication. While some insurance plans may cover this medication for weight loss purposes, others may not, making it expensive for individuals without coverage.
There are also considerations regarding the availability of Semaglutide and the logistics of obtaining and using this medication. Individuals interested in trying Semaglutide for weight loss should discuss these aspects with their healthcare provider and explore all available options to make an informed decision about incorporating this medication into their weight loss journey.
Overall, Semaglutide tablets for weight loss show promise in helping individuals achieve their weight loss goals when used as part of a comprehensive treatment plan. With the guidance of a healthcare provider, individuals can explore the potential benefits of Semaglutide and determine if it is a suitable option for their weight loss journey.
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Stanford researchers have used AI to discover BRP, a naturally occurring peptide that mimics Ozempic’s weight-loss effects—without the nausea or muscle loss. Key findings: 50% reduced food intake in mice and pigs after injection Fat-specific weight loss with no impact on muscle mass Brain-targeted action avoids gut-related side effects The AI-powered hunt analyzed 20,000 human genes to pinpoint this 12-amino-acid molecule, now heading to clinical trials. Could this be the next breakthrough in obesity treatment? 🔬 Study: Nature (March 2025) | DOI: 10.1038/s41586-025-08683-y 🔔 Subscribe for the latest in AI-driven medical breakthroughs and metabolic health! #Ozempic #WeightLoss #AIinMedicine #PeptideTherapy #ObesityTreatment #StanfordMedicine #MedicalBreakthrough #GLP1 #DiabetesResearch #BioTech 📚 Interested in learning more? Check out these amazing science books and resources on Amazon that I've handpicked for you! Dive deeper into the subject and expand your knowledge. 📚 🛍️ Shop my recommendations: https://amzn.to/3AuBl1r 💡 Remember, when you purchase through my link, you're supporting my channel and helping me create more engaging science content for you! It doesn't cost you anything extra, but it means a lot to me. 😊 ⬇️ Don't forget to: Like this video if you enjoyed it! Subscribe for more bite-sized science content! #ScienceInAMinute #LearnWithMe #AmazonFinds