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This is a very brief overview discussion of GLP-1 agonist drugs as they pertain to weight loss. This isn't a discussion about their use in diabetes or treatment of other metabolic, cardiovascular, digestive, or renal diseases.

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The FDA has approved the first weight-loss drug in seven years for people who are either obese or overweight with at least one weight related medical condition. CBS News chief medical correspondent Dr. Jon LaPook joins "CBS This Morning" to explain how the drug works and who might benefit the most from it. Each weekday morning, "CBS This Morning" co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. Subscribe to “CBS This Morning” on YouTube: https://www.youtube.com/user/CBSThisMorning Watch CBSN live: http://cbsn.ws/1PlLpZ7c​ Download the CBS News app: http://cbsn.ws/1Xb1WC8​ Follow "CBS This Morning" on Instagram: http://bit.ly/1Q7NGnY Like "CBS This Morning" on Facebook: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter: http://bit.ly/1Xj5W3p Subscribe to our newsletter: http://cbsn.ws/1RqHw7T​ Try Paramount+ free: https://bit.ly/2OiW1kZ For video licensing inquiries, contact: [email protected]

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Berberine is one of my favorite supplements out there and has been for several years. The reason is simple: berberine helps treat the biggest and most important conditions that people face including weight gain, insulin resistance, and gut dysfunction. It's not only healthy for people who are already healthy, but it's also amazing for people who want to stay healthy! You can use it to assist with weight loss, balance your blood sugar, build more muscle mass, or just optimize your physique. Let's talk about the benefits of berberine and why you can make a strong case to use it. Many of the benefits we are going to be discussing today stem from Berberine's ability to increase something called AMPK or AMP kinase. This is the same enzyme that is increased when you exercise. So when you think about the benefits, think about berberine as a tiny bottle of exercise. It doesn't replace exercise but it's helpful to wrap your head around how it's working. Activating AMPK increases fat burning potential, mitochondrial proliferation in muscle tissue, insulin sensitivity, and much more. With this in mind, let's talk about the benefits: 1. Berberine can help improve insulin resistance and low blood sugar. It has been shown to be as powerful as some medications at lowering blood sugar (metformin). 2. Berberine can help you lose weight. Berberine enhances the effectiveness of diet and exercise. 3. Berberine can help improve your gut health. Berberine increases butyrate production and reduces local inflammation in the gut. 4. Berberine can help lower cholesterol. Some studies show that berberine can reduce cholesterol more effectively than statins. 5. Berberine helps treat metabolic disorders like non-alcoholic fatty liver disease, type II diabetes, PCOS, high blood pressure, obesity, and elevated triglycerides. 6. Berberine can help your brain stay healthy. For everyday general health, use around 500 to 1,000 mg each day. For metabolic conditions use 1,000 to 2,000 mg each day #berberine #nutrition #weightloss #highcholesterol #diabetes #insulinresistance #supplements #naturaltreatment Download my free thyroid resources here (including hypothyroid symptoms checklist, the complete list of thyroid lab tests + optimal ranges, foods you should avoid if you have thyroid disease, and more): https://www.restartmed.com/start-here/ Recommended thyroid supplements to enhance thyroid function: - Supplements that everyone with hypothyroidism needs: https://bit.ly/3tekPej - Supplement bundle to help reverse Hashimoto's: https://bit.ly/3gSY9eJ - Supplements for those without a thyroid and for those after RAI: https://bit.ly/3tb36nZ - Supplements for active hyperthyroidism: https://bit.ly/3t70yHo See ALL of my specialized supplements including protein powders, thyroid supplements, and weight loss products here: https://www.restartmed.com/shop/ Want more from my blog? I have more than 400+ well-researched blog posts on thyroid management, hormone balancing, weight loss, and more. See all blog posts here: https://www.restartmed.com/blog/ Prefer to listen via podcast? Download all of my podcast episodes here: https://apple.co/3kNYTCS Disclaimer: Dr. Westin Childs received his Doctor of Osteopathic Medicine from Rocky Vista University College of Osteopathic medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Childs is no longer practicing medicine and does not hold an active medical license so he can focus on helping people through videos, blog posts, research, and supplement formulation. To read more about why he is no longer licensed please see this page: https://www.restartmed.com/what-happened-to-my-medical-license/ This video is for general informational, educational, and entertainment purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Childs and you. You should not make any changes to your medications or health regimens without first consulting a physician. If you have any questions please consult with your current primary care provider. Restart Medical LLC and Dr. Westin Childs are not liable or responsible for any advice, course of treatment, diagnosis, or any other information, services, or product you obtain through this website or video. #thyroid #hypothyroidism #hashimoto's

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The creator of a controversial diet is facing a lot of heat for an unusual policy. Beatrice Politi reports.

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Drs Akshay Jain and Girish Joshi discuss clinical considerations to keep in mind when someone on GLP-1 therapy is undergoing elective procedures. https://www.medscape.com/viewarticle/glp-1-guidance-reduce-regurgitation-and-aspiration-risk-2024a1000d35?src=soc_yt -- TRANSCRIPT -- Akshay B. Jain, MD: Welcome back to ADA 2024 updates. I'm endocrinologist Dr Akshay Jain from Vancouver in Canada, and today we've got a very special guest. We've got Professor Dr Girish Joshi. Dr Joshi is a professor of anesthesiology and pain medicine at UT Southwestern in Dallas, Texas. He was one of the speakers at a very impactful session that was talking about the postoperative and intraoperative considerations for people who are on GLP-1 therapy. He's here to talk with us about clinical considerations that one needs to keep in mind when someone on glucagon-like peptide 1 (GLP-1) receptor agonist therapy is undergoing elective procedures. Welcome, Dr Joshi. Girish P. Joshi, MD: Thank you, Akshay. It's an honor. Jain: I was attending your session, and I found it very clinically impactful. This is something that we are seeing more and more in clinical practice. For our viewers today, can you share with us, as an anesthesiologist, the potential risks for aspiration and the rates of aspiration that you're seeing in people who are on GLP-1 therapy? Joshi: We don't know the exact rate of aspiration with GLP-1 therapy because there are no good studies, but there are several anecdotal reports, including several personal communications where people have contacted me and the American Society of Anesthesiologists (ASA). I'm the chair of the task force for these GLP-1 recommendations developed by the ASA. To give an example, one of the cases reported to me was from a colleague in Dallas where a patient, otherwise completely healthy, came in for a shoulder arthroscopy — a simple outpatient procedure in a freestanding ambulatory surgery center. Surgery went fine. At the end of the procedure, she regurgitated gastric content and aspirated, and then had to be taken to the intensive care unit (ICU) and she spent 7 days in the ICU. Retrospectively, it was recognized that she was on GLP-1 therapy for weight loss, which was not disclosed. This was just before the ASA came up with the guidance, basically, so people didn't know that GLP-1 receptor agonists do increase the risk for aspiration. Jain: That's a really good point straight from your clinical practice. For our viewers who may not be familiar with the guidelines, could you tell us, in a nutshell, for people on GLP-1 therapy who are going in for an elective procedure that requires general anesthesia, what would be the recommendations for holding GLP-1s? Joshi: I have to first emphasize that currently, the evidence to provide any guidance is sparse, and whatever studies are available are basically questionable or of poor quality. With that said, the reason why the ASA came up with the guidance was to inform our colleagues, anesthesiologists, as well as our colleagues from surgery and other proceduralists of this concern about increased regurgitation and aspiration in patients on GLP-1 receptor agonists. That was the primary aim. Because the evidence is sparse, we basically came up with different approaches to decrease or mitigate the risk for regurgitation and aspiration. It starts with having a collaborative discussion, including the patients, or shared decision-making with the physicians and the patient regarding the potential risks, so mention to the patient that there is a potential risk. Then, avoid the elective procedures in patients at high risk. Examples of patients at high risk would be those who are basically in the escalation phase of the GLP-1 therapy, patients with prior history of gastroparesis, or patients on drugs that can cause gastroparesis. I don't know whether you remember I had an algorithm I developed and presented at the American Diabetes Association (ADA) meeting, where I presented the potential risk factors. If the patients are at risk for regurgitation and aspiration, that's the patient population we've got to be extra careful with. Maybe start off withholding the drug if the patients are on, say, a weekly therapy, then 1 week before, though the evidence is minimal. Nevertheless, more importantly, avoid elective procedures during that escalation phase in this patient population. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-guidance-reduce-regurgitation-and-aspiration-risk-2024a1000d35?src=soc_yt

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