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Three drugs: Liraglutide (Saxenda), Semaglutide (Wegovy), and Tirzepatide (Zepbound / Mounjaro) have been licensed for weight loss in patients who are overweight or obese. In this video I will discuss the mechanisms of action of these medicines, the licensed indications, method of administration, efficacy, side effects, and what happens to body weight after stopping treatment. TIMESTAMPS: 00:00 Introduction 00:26 Licensed Drugs 01:37 Mechanisms of Action 05:45 Licensed Indications 06:32 Method of Administration 07:14 Efficacy 08:49 Side Effects 09:47 Stopping Treatment References: Liraglutide: . SCALE Diabetes trial: https://pubmed.ncbi.nlm.nih.gov/26284720/ . SCALE Maintenance trial: https://pubmed.ncbi.nlm.nih.gov/23812094/ . SCALE Obesity & Prediabetes: https://pubmed.ncbi.nlm.nih.gov/26132939/ Semaglutide: . STEP 1 trial: https://pubmed.ncbi.nlm.nih.gov/33567185/ . STEP 2 trial: https://pubmed.ncbi.nlm.nih.gov/33667417/ . STEP 3 trial: https://pubmed.ncbi.nlm.nih.gov/33625476/ . STEP 4 trial: https://pubmed.ncbi.nlm.nih.gov/33755728/ Tirzepatide: . SURMOUNT 1: https://pubmed.ncbi.nlm.nih.gov/35658024/ . SURMOUNT 2: https://pubmed.ncbi.nlm.nih.gov/37385275/ . SURMOUNT 3: https://pubmed.ncbi.nlm.nih.gov/37840095/ . SURMOUNT 4: https://pubmed.ncbi.nlm.nih.gov/38078870/ Liraglutide vs Semaglutide: . STEP 8 trial: https://pubmed.ncbi.nlm.nih.gov/35015037/ What happens to body weight after stopping treatment: . SURMOUNT 4: https://pubmed.ncbi.nlm.nih.gov/38078870/ . STEP 4 trial: https://pubmed.ncbi.nlm.nih.gov/33755728/ . Liver Inte. 2019;39:941-949: https://pubmed.ncbi.nlm.nih.gov/30721572/ Other References: Effect of dual GIP / GLP-1 on Weight loss: https://pubmed.ncbi.nlm.nih.gov/36909312/ This video is purely of educational purposes and is intended for primary care physicians. It is not and should not be used by patients to treat themselves. The advice is to always speak to your doctor and follow his or her advice with regards to any condition you have or any treatment you are likely to undertake. #semaglutide #tirzepatide #wegovyweightloss #mounjaroweightloss #weightlossmedication #saxenda #glp1

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Losing weight after 60 is difficult and belly fat can be particularly stubborn! It sneaks up on you in our 60s, even if you have been doing all the right things to stay healthy! In this video we talk about the reason belly fat is so prevalent as we get a little older and what we can do to get rid of it! This is without any strict or crazy diets and instead just 5 tiny habits that we can tweak. There is not denying that as we get older our estrogen starts to decline and that our metabolism does slow down. But there are things that can have a very positive effect on countering these natural processes. In this video, I will also mention several ways to minimize stress, which is a great contributor to the production of cortisol which encourages the growth of belly fat. Let's discuss how to lose weight at any age! It really is possible! Are you trying to control your belly fat in your sixties? What things do you incorporate into your lifestyle to minimize its presence? Please leave your comments in the section below and help other Sixty and Me sisters deal with this annoying but not seemingly inevitable challenge? *******MAKE MORE FRIENDS THIS YEAR!***** If you believe in our mission to improve the lives of women over 60, please consider supporting us on Patreon. Learn how here: https://www.patreon.com/sixtyandme *****GET MORE FROM SIXTY AND ME***** Subscribe to our newsletter https://app.monstercampaigns.com/c/nz10ws1ql656rrzkqocf/ Subscribe to my YouTube channel: http://www.youtube.com/subscription_center?add_user=sixtyandme Also, remember to check out everything Sixty and Me has to offer here: http://sixtyandme.com/start #bellyfat #losingweight #sixtyandme
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Smart nutrition is the foundation of real progress in fitness. Without the right balance of protein, fats, and carbs, your body just can’t recover or grow properly. Supplements aren’t magic — they’re tools to help you get more out of your training. Protein helps with muscle recovery, creatine gives you that extra strength boost, omega-3s fight inflammation, and NAD+ supports energy and overall cell health. It’s all about combining the right stuff with a smart approach — that’s when the real results show up.
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GLP1 medications like Ozempic and Wegovy for weight loss are all the rage right now. But how safe are these diabetes medications? On this show, Karolyn talks with diabetes expert Dr. Daemon Jones about these drugs. Dr. Jones is a respected naturopathic physician and founder of the Healthy Daes Naturopathic Medical Center in Washington, DC. She explains how these drugs work, how effective they are, and potential side effects. If you are taking one of these drugs or considering them, you won't want to miss this show. Five To Thrive Live is broadcast live Tuesdays at 7PM ET and Music on W4CS Radio – The Cancer Support Network (www.w4cy.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com). Five To Thrive Live Podcast is also available on Talk 4 Media (www.talk4media.com), Talk 4 Podcasting (www.talk4podcasting.com), iHeartRadio, Amazon Music, Pandora, Spotify, Audible, and over 100 other podcast outlets.
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Belly fat reduction and emotional stress relief come together in this 50-minute yoga session designed to strengthen your abs and calm your mind. ✔️ Core-focused flows to target belly fat and build strength ✔️ Breathwork to release emotional stress and tension ✔️ Gentle movements to improve digestion and energy flow ✔️ Perfect for all levels—practice anytime, anywhere Unroll your mat and enjoy lightness in your body and calm in your mind. For more updates 1. We go live daily at 6 am, 7 am, 8 am, 5 pm, 6 pm, 7 pm. 2. Visit our certified organic Chemical-Free Skincare Trehi Organics: https://trehiorganics.com/ Kumkumadi Oil – https://www.amazon.in/dp/B0DK2ZZM56 Face Toner – https://www.amazon.in/dp/B0DK3HYQKK Hair Oil – https://www.amazon.in/dp/B0DK332FQJ Body Oil – https://www.amazon.in/dp/B0DK3234R4 #BellyFatBurn #StressRelief #YogaForWeightLoss #CoreStrength #DailyYoga #FatBurningYoga #YogaForBeginners #Mindfulness #SelfCare #YuvaapYoga