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Here’s what I eat in a day to lose weight and shred fat every meal packed with high protein, low fluff. If you’re cutting or trying to get lean while keeping muscle, this is for you. Quick, easy, and effective meals that fuel results and taste good too. Fat loss isn’t about starving it’s about eating smart.

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👀 Do you want to get fit without dieting or exercising by tricking your body? This sounds like sci-fi, or like a scammy ad for a fat burning supplement. However, given recent advances in exercise mimetics and strong momentum behind treating obesity pharmacologically (most notably, semaglutide - Ozempic/Wegovy and tirzepatide - Mounjaro/Zepbound), this idea could reality sooner than some expect. 🧠 In this video we will discover SLU-PP-332, a small molecule that mimics endurance training and dieting in mice - without exercise or eating less. We will cover 1) the biochemical basics of exercise mimetics and mechanisms of action, 2) take a look at pre-clinical data of different compounds, and 3) as always, review chemistry concepts. https://www.patreon.com/totalsynthesis 🚀 Thanks to all channel supporters!!! https://www.instagram.com/totalsynthesis_official/ 👉 Follow me on Instagram for updates on random research, mechanism quizzes and interesting news! https://total-synthesis.com https://total-synthesis.com/exercise-mimetics-trick-your-body-into-burning-fat/ Disclaimer - This channel does not provide medical advice! No information on this channel is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of information on Youtube. 00:00 Trick your body into losing weight - is it possible? 01:22 Obesity problem, logic behind using drugs and limitations 02:31 GLP1 agonists 03:01 Exercise mimetic basics 04:04 Resveratrol's exercise mimicry, health benefits and unexpected effects 06:03 ERR up/downregulation can trigger major effects - transgenic and knock-out mice 09:18 Drug design logic behind SLU-PP-332 11:02 Organic synthesis of SLU-PP-332 (too easy) 11:32 Molecular, structural, physiological and metabolic effects of SLU-PP-332 15:05 Outlook and conclusion Key references: - PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism | Oxidative Medicine and Cellular Longevity, 2020, 1452696 - Caloric restriction and exercise “mimetics’’: Ready for prime time? | Pharmacological Research 2016, 103, 158 - Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha | Cell 2006, 127, 1109 - Distribution and Effects of Estrogen Receptors in Prostate Cancer: Associated Molecular Mechanisms | Frontiers in Endocrinology 2022, 12, 811578 - Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma | J Med Chem 2005, 48, 3107 - Exercise and PGC-1 alpha-Independent Synchronization of Type I Muscle Metabolism and Vasculature by ERR gamma | Cell Metabolism 2011, 13, 283 - Estrogen-related receptor-α coordinates transcriptional programs essential for exercise tolerance and muscle fitness | Mol Endocrinol 2014, 28, 2060 - Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity | ACS Chem. Biol. 2023, 18, 756 - A Synthetic ERR Agonist Alleviates Metabolic Syndrome | J. Pharmacol. Exp. Ther. 2023, 001733 Another related SLU-PP compound with more chemistry information behind it: Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915 | Eur J Med Chem 2023, 258, 115582 Some recommended books on organic synthesis: - Clayden, Greeves, Warren; Organic Chemistry (basic organic chemistry knowledge) - Wyatt, Warren; Organic Synthesis: The Disconnection Approach (excellent introduction to retrosynthesis) - Kurti, Czako; Strategic Applications of Named Reactions in Organic Synthesis (extensive toolkit of functional group reactions and applications thereof with common conditions) - Nicolaou; Classics in Total Synthesis 1-3 (the ultimate total synthesis trilogy) - Nicolaou; Molecules That Changed the World (the world's most important molecules and their impact on everyday life) - Carreira, Kvaerno; Classics in Stereoselective Synthesis (compilation of the groundbreaking methods of stereoselective synthesis and application to synthesis of stereochemically complex structures)

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As more and more people become interested in the ketogenic diet, there is a growing need for a comprehensive guide that can help individuals sustain this lifestyle in the long term. This is where Lifetime Keto comes in. This guide is designed to provide valuable information and resources to help individuals achieve sustained success with their ketogenic living.

About Lifetime Keto

Lifetime Keto is not just another fad diet. It is a way of life that can help individuals achieve their health and wellness goals. This comprehensive guide provides a wealth of information on the ketogenic diet, including what it is, how it works, and how to successfully implement it into your daily routine.

Unlike other diets that rely on restricting calories or certain food groups, the ketogenic diet focuses on consuming high-fat, low-carb foods to promote fat burning and weight loss. By following the principles of the ketogenic diet, individuals can experience increased energy levels, improved mental clarity, and better overall health.

However, sustaining a ketogenic lifestyle can be challenging, especially for beginners. That’s where Lifetime Keto comes in. This guide offers practical tips, meal plans, and recipes to help individuals stay on track with their ketogenic living journey.

The Benefits of Lifetime Keto

One of the key benefits of following Lifetime Keto is the potential for weight loss and improved body composition. By reducing carbohydrates and increasing healthy fats in your diet, you can kickstart your body’s natural fat-burning mechanisms and shed excess pounds.

In addition to weight loss, the ketogenic diet has been shown to have numerous other health benefits. It can help lower blood sugar levels, reduce inflammation in the body, and improve overall heart health. By following the principles outlined in Lifetime Keto, individuals can experience these benefits firsthand.

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Furthermore, the ketogenic diet is known for its ability to stabilize blood sugar levels and reduce cravings for sugary and processed foods. This can be incredibly helpful for individuals looking to break free from unhealthy eating habits and develop a healthier relationship with food.

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While the ketogenic diet can be incredibly effective for weight loss and overall health, it’s important to approach it with the right mindset. Setting realistic goals, staying consistent, and seeking support from others can all contribute to long-term success with Lifetime Keto.

Meal planning and preparation are also key components of sustaining a ketogenic lifestyle. By planning your meals ahead of time and stocking your kitchen with keto-friendly foods, you can make it easier to stick to your dietary goals and avoid temptations.

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A: The timing of results can vary from person to person, but many individuals start to see changes in their energy levels, weight, and overall health within a few weeks of starting the ketogenic diet. Consistency and dedication are key to achieving long-term success with Lifetime Keto.

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Get access to my FREE resources 👉 https://drbrg.co/49SkDVX Check out these surprising things you need to know about vitamin C! Check out Dr. Berg’s Vitamin C Complex Here: 🛒 https://bit.ly/3tZrDi0 OR https://amzn.to/3DwYTQG DATA: https://www.cancer.gov/about-cancer/treatment/cam/patient/vitamin-c-pdq https://www.sciencedirect.com/science/article/pii/S2213231720302123 0:00 Introduction: Vitamin C explained 0:05 What is ascorbic acid? 1:45 Surprising things about vitamin C 8:10 Check out my video on what vitamin C does! Today, let’s talk about vitamin C. I want to increase your awareness of the type of vitamin C you might be taking and the type you should be taking. According to recent editions of the dictionary, ascorbic acid is the same thing as vitamin C. But, is the type of ascorbic acid in most vitamin supplements actually similar to vitamin C found in nature? In my opinion, no. Ascorbic acid (synthetic vitamin C) is made from glucose and other chemicals. Personally, I would only take ascorbic acid for a short-term detox cleanse, not on a long-term basis. The best type of vitamin C to get is vitamin C from food or food-based vitamins. Foods that have the most vitamin C: • Leafy greens • Berries • Lemons • Organ meats • Bell peppers • Sauerkraut Things you need to know about vitamin C: 1. There is little to no benefit from taking high doses of ascorbic acid. 2. Most vitamin C sold is fake and made from sugar. 3. Vitamin C is not absorbed well if you consume sugar at the same time. 4. A mega-dose of ascorbic acid may cause oxidation, diarrhea, and bloating. ADD YOUR SUCCESS STORY HERE: https://www.drberg.com/add-client-success-story?utm_source=youtube&utm_medium=description FREE COURSE➜ ➜ http://bit.ly/BulletproofImmuneSystemCourse Dr. Eric Berg DC Bio: Dr. Berg, age 56, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media. Follow Me On Social Media: Facebook: https://bit.ly/FB-DrBerg Instagram: https://bit.ly/IG-DrBerg TikTok: https://bit.ly/TikTok-DrBerg DR. BERG'S SHOP: http://shop.drberg.com/ ABOUT DR. BERG: https://www.drberg.com/dr-eric-berg/bio Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. #keto #ketodiet #weightloss #ketolifestyle Thanks for watching! I hope this helps you better understand vitamin C and what type of vitamin C to take.

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#himsstocktoday #himsandhersstockanalysis #himsstocknews The Hims and Hers stock faced a dramatic 26% decline following a food and drug administration announcement regarding ozempic drug shortage status changes. The stock market news reflects growing concerns as the company can no longer sell generic versions of weight loss drugs, significantly impacting their business model. Join us for the latest financial news and business news as we analyze the implications of this development for investors and the broader healthcare sector.