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පර්යේෂණවලින් පෙනී යන්නේ ඉන්සියුලින් ලබා ගැනීම ආරම්භ කරන පුද්ගලයින් පළමු වසර තුළ බොහෝ විට බර වැඩි වන බවයි. සාමාන්‍ය බර වැඩිවීම රාත්තල් 4 ක් පමණ වන නමුත් සමහර පුද්ගලයින් රාත්තල් 11 ක් හෝ ඊට වැඩි විය හැකිය [1]. මෙය සිදු වන්නේ ඉන්සියුලින් ඔබේ රුධිරයේ 00:00 අධික සීනි ප්‍රමාණයක් ඇති විට මේදය ලෙස සීනි ගබඩා කිරීම ශරීරය කරන බැවිනි. 01:00 සමහර රුධිර පීඩන ඖෂධ සීනි වැඩි කළ හැක. 03:00 බර වැඩි වන විට දියවැඩියාවද වැඩි වේ. 04:30 ඉන්සියුලින් අක්මාවේ මේද තැන්පත් වීමට හේතු වේද? 05:00 නව ඖෂධ රාශියක් තිබේ. 06:00 sglt2 ඖෂධ ගැන ඔබේ වෛද්‍යවරයාගෙන් විමසන්න. 0820 ඉන්සියුලින් කුසගින්න වැඩි කරයි. 13:00 රුධිරයේ සීනි මට්ටම ඉතා පහත වැටීම වළක්වා ගැනීම සඳහා ඔබ වැඩිපුර ආහාර ගන්නවා. 17:40 ඔයාට සල්ලි තියෙනවා නම් මේ බෙහෙත ඔයාට උදව් වෙයි. 20:00 සීමිත දීමනාව: ආහාර ගැනීමෙන් පසු රුධිරයේ සීනි මට්ටම සඳහා කරන වියදම් සඳහා මුදල් ආපසු ගෙවීම. ඔබ 2 වර්ගයේ නම්, බර වැඩිවීමට හේතු නොවන තවත් බොහෝ ඖෂධ තිබේ. ඒවාට ප්‍රධාන වශයෙන් SGLT2 නිෂේධක ඖෂධ, DPP4 ඖෂධ සහ පැරණි විශ්වාසවන්ත මෙට්ෆෝමින් ඇතුළත් වේ. SGLT2 ඖෂධවලට වකුගඩු සහ හදවත ආරක්ෂා කිරීමේ අමතර ප්‍රතිලාභ ඇත. වඩාත් සවිස්තරාත්මක වීඩියෝවක් සඳහා ඉහත සබැඳියේ වීඩියෝව බලන්න. ඔබ 1 වර්ගයේ නම්, ඔබට ඉන්සියුලින් අවශ්‍ය වේ, නමුත් රනිල කුලයට අයත් බෝංචි සහ කොළ පැහැති එළවළු මත පදනම් වූ ආහාර වේලක් අනුභව කිරීමෙන් ඔබට අවශ්‍යතාවය අවම කර ගත හැකිය. ඔබ ඉන්සියුලින් ගන්නා විට, ඔබේ ශරීරය මුත්රා හරහා කැලරි නැතිවීම නතර කරයි. මෙයින් අදහස් කරන්නේ ඔබ ඔබේ ශරීරයේ වැඩිපුර කැලරි තබා ගන්නා බවයි, එය බර වැඩිවීමට හේතු විය හැක. එසේම, ඉන්සියුලින් ඔබට බඩගිනි දැනිය හැකි බැවින් ඔබට වැඩිපුර ආහාර අනුභව කළ හැකිය. SGLT-2 Inhibitors or sodium-glucose cotransporter 2 inhibitors like canagliflozin, ertugliflozin, dapagliflozin, and empagliflozin may lead to weight loss and improved blood sugar control in people with type 2 diabetes. We will go into each one of them in detail later in this video. They are approved by most governments including the Therapeutic Goods Administration or TGA in Australia, FDA in America and The Central Drugs Standard Control Organisation (CDSCO) in India. Some of the common Diabetic medications cause weight gain. They include Insulin, Sulfonylureas like glipizide, gliclazide, tolbutamide, Metiglinides like repaglinide and Thiazolidinediones like pioglitazone. Metformin is a common medication used to manage type 2 diabetes. While it wasn’t specifically designed as a weight loss drug, some studies have found a link between metformin and weight loss. Here’s what you need to know: How Metformin Works: Metformin primarily lowers blood sugar levels by reducing the amount of glucose released by the liver. It also improves insulin sensitivity, allowing muscles to use glucose more efficiently. Lower insulin levels can lead to better overall health and reduced risk of complications associated with high blood sugar. Metformin and Weight Loss: The relationship between metformin and weight loss is not fully understood, but several theories exist: Reduced Hunger Cues: Some studies suggest that metformin may affect hunger cues, leading to decreased appetite. Improved Blood Sugar Control: Better blood sugar management may indirectly contribute to weight loss. On average, people with diabetes taking metformin experience weight loss ranging from 4 to 7 pounds per year. However, individual responses can vary. Can Non-Diabetic Individuals Take Metformin for Weight Loss? Yes, metformin can be used for weight loss even if you don’t have type 2 diabetes. It is very unlikely cause hypoglycaemia in diabetics if used alone or with SGLT2 medications. Hypoglycaemia is a serious condition which can be fatal if not treated quickly. While we are in the middle of the video, it is essential to consult with a healthcare provider before starting any medication, including metformin, for weight management. SGLT2 inhibitors, also known as “gliflozins” or “flozins,” are a group of medications initially developed to manage type 2 diabetes. Their primary function is to lower blood glucose levels by increasing the excretion of glucose in the urine. However, their benefits extend far beyond glycemic control. https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or Time 8.15pm-3-Jun-14

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Just got home from the Improvathon. Ok, ok, so it's well into early Sunday morning so doesn't really count as day 49. Plus, I didn't really exercise and my food intake was hideous. I'm delirious since I've been up for about 42 hours without sleep. But, I had so much guilt over not exercising or posting a video I had to at least do this much.

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