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David Nathan, MD, Professor at Harvard Medical School, and Director of the Diabetes Center at Massachusetts General Hospital, shares why metformin remains the best first-line therapy for type 2 diabetes. To learn more, visit and subscribe to the NIDDK Diabetes Discoveries & Practice blog: https://www.niddk.nih.gov/health-information/professionals/diabetes-discoveries-practice/metformin-first-choice

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In this episode, I explore a crucial question for anyone on GLP-1 medications: can we get our bodies to respond naturally to GLP-1 again? After noticing changes in weight and health while attending a fitness conference, I began wondering about the long-term metabolic effects of GLP-1 treatments and how we might return to normal hormone sensitivity. I share personal experiences, discuss insights from Dr. Jason Fung's work, and break down practical strategies for anyone hoping to restore natural hormone balance—whether they’re on medication or not. Top Topics: GLP-1 Desensitization & Long-Term Use: I ask the big question—does our body ever go back to normal GLP-1 function after extended use of medication? This curiosity was sparked by my own experience on a 10mg dose and thinking ahead about eventually coming off it. I also compare this situation to insulin resistance, explaining how too much of a good thing can make the body ignore it entirely. Insights from Dr. Jason Fung: I highlight ideas from Dr. Fung, a kidney specialist and metabolism expert. He emphasizes how hormones control weight gain and loss, and how overexposure leads to hormonal resistance. It's a wake-up call to consider what our bodies are really doing with all the insulin, glucose, and GLP-1 they're exposed to. How to Resensitize to GLP-1 Naturally: The second half of the episode focuses on practical, everyday actions we can take to help our body become responsive again. These include: Exercise: Cardio and resistance training both help burn off excess sugar and improve hormone sensitivity. Stress Reduction: Managing cortisol through deep breathing, prayer, or journaling can restore hormone balance. Sleep: Quality sleep is non-negotiable. Poor sleep can suppress GLP-1 and increase hunger hormones. Time-Restricted Eating: This strategy gives your body a break from constant food intake and encourages it to use stored energy, leading to better glucose and insulin regulation. Takeaways: Hormonal resistance isn't a life sentence. We can take actionable steps—like moving more, eating smarter, and prioritizing rest—to help our bodies work better naturally. GLP-1 medication might be part of the healing journey, but these daily habits are how we stay healthy in the long term. Whether you're just starting your weight loss journey or thinking about the long haul, there's hope for rebalancing your metabolism and getting back to a healthier set point. Keep learning, keep trying, and know that you're not alone in this.

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Intuitive eating and losing weight— are they compatible? Can you eat intuitively and lose weight? ➤ ONLINE NUTRITION COACHING IS OPEN! : https://edukale.com/nutrition-coaching-sessions/ ➤ Make sure to get your FREE optimal Wellness and Nutrition Checklist! https://bit.ly/2JTb0wv If you’ve been watching my videos for a while, you probably know that I eat intuitively and love to promote this way of eating. This has led to many questions surrounding weight: can you eat intuitively and lose weight? Does intuitive eating work for weight loss? Here’s the truth on intuitive eating and weight loss. In this video, I'll talk about losing weight with intuitive eating, and how weight loss can happen but shouldn't be the main focus. I'll address the question "Will I gain weight with intuitive eating?" And also guide you if you are looking for how to lose weight. Hopefully this video gives you the insight you are looking for on intuitive eating and weight loss! ↠ Don't forget to like this video and subscribe! __________ • Read my blog post for more info and my sources: https://edukale.com/can-you-actually-lose-weight-with-intuitive-eating/ • Check out my blog! https://edukale.com/ • Follow me on Pinterest! https://www.pinterest.com/edukale/ • Follow me on Instagram: https://www.instagram.com/edukalebylucie/ ↠VIDEOS MENTIONED Intuitive eating playlist: https://www.youtube.com/playlist?list=PLJbjPbdqPjM76OSGuKwTgj5GOA8a2_fxP Set point theory: https://youtu.be/41XGR_wszIk The problem with cheat meals: https://youtu.be/zTpNzs5QOPg How to stop binge eating: https://youtu.be/LSOYZoMddFE Why diets don't work: https://youtu.be/hJ8jFWhipxY __________ ▹ The camera I use: https://amzn.to/3aHXzwr ▹Yvette Sports - https://is.gd/83eFFL Discount codes: Lucie15 for 15% off sitewide & Lucie20 for 20% off on orders $109+ Music by T1MB3R - On the Edge - https://thmatc.co/?l=2B58EEEA Music by Mark Generous - Meganne - https://thmatc.co/?l=F1D06443 Music by Ryan Little - flew da coupe. - https://thmatc.co/?l=22E02155 Music by Clans - Mellow - https://thmatc.co/?l=C0C1D6AA __________ All information posted is for educational and informational purposes ONLY. While I am a nutritionist with a master’s degree in biology specialized in nutrition and health, I am NOT a doctor or dietician. I'm just stating my informed opinion, and these videos are NOT intended as a substitute for professional medical advice. Any decision to act upon the advice given in these videos is done at your own risk. DISCLAIMER: Links included in this description might link to a product of which I am an affiliate. Purchasing the product via this link could potentially provide me with a commission, at no additional charge to you!

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👉Please Check the 👉First Comment of this video for the Official Website Link of "Puravive" Wondering if Puravive is the right weight loss supplement for you? In this in-depth review, I share my honest experience after trying Puravive, breaking down its ingredients, benefits, and whether it truly delivers on its promises. Is it a scam or a game-changer for weight loss? Watch till the end to see real results, expert insights, and my final verdict on whether you should buy it. Don’t forget to like, comment, and subscribe for more weight loss product reviews! puravive review,puravive honest review,puravive customer review,puravive reviews,puravive reviews 2025,puravive,purevive review,puravive ingredients,puravive weight loss,puravive work,buy puravive,puravive supplement,puravive price,puravive pills,puravive buy,puravive official website,puravive capsule,does puravive works,puravive us,pura vive review,puravive bat,puravive 2025,purevive Disclaimer- Some content is used for educational purposes under fair use. Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is permitted by copyright statutes that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. All credit for copyright material used in the video goes to the respected owner. Affiliate Disclaimer: Some of the links mentioned in the video and in the description are my affiliate links, if you use them and buy something, I’ll receive a small commission. These commissions help support the channel and allow me to continue to record more of these Free Training videos for you guys. Thank you very much for your support!

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