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Calling all those with a passion for cardiovascular prevention! In this episode of the CardioNerds Cardiovascular Prevention Series, we take a deep dive into the world of glucagon-like peptide-1 (GLP-1) receptor agonists. Along the way, you’ll hear about the biology of the GLP-1 molecule and its related peptides, learn more about how GLP-1 agonists promote glycemic control, weight loss, and cardiometabolic health, and explore the current body of literature supporting the individualized application of these medications to patients with diabetes, obesity, and/or ASCVD. Join Dr. Christian Faaborg-Andersen (CardioNerds Academy Fellow and Internal Medicine Resident at MGH), Dr. Gurleen Kaur (Director of the CardioNerds Internship, Chief of House Einthoven, and Internal Medicine resident at BWH), and Dr. Rick Ferraro (CardioNerds Academy House Faculty and Cardiology Fellow at JHH) for a wide-ranging discussion on GLP-1 and GIP agonists with Dr. Dennis Bruemmer (Cardiologist and Director of the Center for Cardiometabolic Health in the section of Preventive Cardiology at the Cleveland Clinic). Show notes were drafted by Dr. Christian Faaborg-Andersen. Audio editing was performed by CardioNerds Academy Intern, student Dr. Tina Reddy. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - GLP-1 Agonists: Mechanisms to Applications The selection and dosing of GLP-1 and GIP agonists (GLP-1s and GIPs) depends on their intended use as an anti-glycemic or anti-obesity agent. The cardiovascular benefits of GLP-1s and GIPs may be independent of improvements in glycemic control, and in part be driven by reduction in inflammation, a key driver of arterial plaque formation. In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin. Tirzepatide is a dual agonist that activates GIP and GLP-1 receptors. GIP is highly expressed in the brain, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Caution should be used with GLP-1 agonists in patients with long-standing diabetes complicated by gastroparesis, as well as incompletely treated diabetic retinopathy. GI upset is not uncommon with GLP-1/GIP agonists, and switching to a different agonist is unlikely to help. Show notes - GLP-1 Agonists: Mechanisms to Applications What are the mechanisms of action by which GLP-1 and GIP controls blood sugar and body weight? Glucagon-like peptide-1 (GLP-1) is an endogenous hormone that is secreted in response to an oral glucose load. It promotes insulin release, inhibits glucagon secretion, and slows gastric emptying via the brain-intestine axis, leading to satiety. GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%. These medications include semaglutide, liraglutide, and dulaglutide. Glucose-dependent insulinotropic polypeptide (GIP) is also an endogenous hormone, similarly secreted by the body in response to an oral glucose load such as a meal. GIP is highly expressed in the arcuate nucleus and hypothalamus, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Tirzepatide is a dual GLP-1/GIP agonist. What is the role of GLP-1/GIP agonists in patients with overweight/obesity and/or type 2 diabetes? How does the dosing of GLP-1/GIP medications change with their intended disease target?
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Hola todos! El dia de hoy les voy a compartir mis mejores tips y consejos para iniciar la dieta keto hoy mismo. No es tan complejo y complicado como podemos pensar, la clave es ser constante y bajar esos gramos de carbohidratos. Estan listos? Si aun no lo han hecho síganme en mi red social principal que es Instagram para estar pendientes de los posts y fotos diarias. https://www.instagram.com/manuelaecheverri/?hl=en Calculador de Macros https://www.ketoconnect.net/calculator/
Ozempic And Weight Loss The Happy Weight Podcast 15 Full Episode
Drugs like Ozempic promise a quick fix to shedding kilos, but these so-called 'wonder drugs' can be risky and even deadly. ► WATCH Full Episodes on 9NOW: https://9now.app.link/uNP4qBkmN6 ► Subscribe here: http://9Soci.al/chmP50wA97J *Synopsis | Reshaping the World (2024)* Blame it on our success as a wealthy western nation, but we live with an enormous problem. Our size. Too many Australians are too big. Everyone knows excess weight is bad for our health, but battling the bulge is a fight too few of us win. And that’s the reason drugs like Ozempic are in such demand. They promise a quick fix to losing kilos, even though they’re not designed as weight-loss remedies. But as Dimity Clancey reports, users need to be very cautious. The Ozempic hype is starting to wither, replaced with the reality that it and similar drugs are risky, even deadly. *MORE VIDEOS like this one* ► https://www.youtube.com/watch?v=3nvoumJsjus ► https://www.youtube.com/watch?v=2l25ixKvYtk ► https://www.youtube.com/watch?v=SvQGfwYIOA0 FOLLOW 60 Minutes Australia ► WATCH more of 60 Minutes Australia: https://www.60minutes.com.au ► Facebook: https://www.facebook.com/60Minutes9 ► Twitter: https://twitter.com/60Mins ► Instagram: https://www.instagram.com/60minutes9 ABOUT 60 Minutes Australia For over forty years, 60 Minutes Australia have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Tara Brown, Amelia Adams, Adam Hegarty, Dimity Clancey and Nick McKenzie look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes Australia. #60MinutesAustralia
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Beware Of Keto Diet Heart Attacks By Keto Diet
Shark Tank is a popular reality TV show that features entrepreneurs pitching their business ideas to a panel of wealthy investors, known as the “sharks.” In one episode, the sharks were presented with a product called Keto Pills, a dietary supplement that claims to help people lose weight by promoting ketosis in the body. The episode generated a lot of buzz and controversy, as the sharks debated the efficacy and safety of the product. Let’s take a closer look at this episode and dissect the arguments made by both the entrepreneurs and the sharks.
Entrepreneurs’ Pitch
The entrepreneurs behind Keto Pills touted their product as a revolutionary weight loss solution that could help people achieve their fitness goals without having to follow strict diets or exercise regimens. They claimed that the pills were made from natural ingredients and had been scientifically proven to induce ketosis in the body, resulting in rapid weight loss. The entrepreneurs also shared testimonials from satisfied customers who had seen significant results after using the product.
Overall, the entrepreneurs presented Keto Pills as a game-changer in the weight loss industry, promising users a quick and easy way to shed pounds and achieve their desired body goals. They were confident in the effectiveness of their product and believed that the sharks would see the potential for huge profits in this lucrative market.
However, the sharks had some concerns about the safety and viability of Keto Pills as a weight loss solution. Some of the sharks questioned the scientific evidence behind the product’s claims, citing the lack of independent studies or peer-reviewed research to support its efficacy. Others raised red flags about the potential side effects of the pills and expressed skepticism about the long-term effects of inducing ketosis artificially.
Sharks’ Responses
Each of the sharks had their own reservations about Keto Pills, with some expressing outright disbelief in the product’s effectiveness and others raising questions about the entrepreneurs’ business strategy. Mark Cuban, known for his no-nonsense approach, was the first to voice his doubts about the product, citing the lack of concrete data to back up the entrepreneurs’ claims.
Barbara Corcoran, on the other hand, questioned the scalability of the business and the sustainability of the product in an increasingly competitive market. She pointed out that the weight loss industry is saturated with similar products and questioned whether Keto Pills could stand out among the competition.
Ultimately, none of the sharks were persuaded to invest in Keto Pills, with most citing the lack of reliable scientific evidence and the saturated nature of the weight loss market as their reasons for passing on the opportunity. The episode served as a cautionary tale about the importance of thorough research and due diligence when evaluating new products and business ideas.
Lessons Learned
The Shark Tank episode featuring Keto Pills shed light on the challenges of bringing a new product to market, especially in the competitive and skeptical world of weight loss supplements. It underscored the importance of presenting solid data and research to back up product claims, as well as the need for a clear and compelling business strategy to attract investors.
Entrepreneurs looking to pitch their ideas on Shark Tank or any other platform should be prepared to answer tough questions and address any concerns raised by potential investors. They should also be ready to pivot their business model or product offering based on feedback received during the pitch process, as flexibility and adaptability are key to success in the ever-evolving world of entrepreneurship.
While Keto Pills may not have won over the sharks on this episode, the entrepreneurs behind the product can take this experience as a learning opportunity to refine their pitch and strengthen their product offering. With the right amount of perseverance and determination, they may still find success in bringing Keto Pills to market and helping people achieve their weight loss goals in a safe and effective manner.
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Overall, the Shark Tank episode with Keto Pills serves as a valuable lesson for entrepreneurs and investors alike, highlighting the importance of due diligence, research, and innovation in the fast-paced world of business. It also underscores the need for transparency and integrity when promoting new products, as consumers and investors are increasingly savvy and discerning in their purchasing decisions.
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Join us on a groundbreaking journey in our latest interview from Town & Country Compounding. We sit down with Dr. Jeffrey A. Morrison, a board-certified physician in integrative and functional medicine and the founder of The Morrison Center in New York City. Explore how Dr. Morrison's innovative practices, which beautifully blend scientific advancements and holistic health, are setting new standards in patient care. Dr. Morrison's center, recognized for its custom treatment plans and a holistic approach, stands at the forefront of transforming healthcare. His expertise covers a wide range of specialties from Microdosing GLP-1s to Sermorelin therapies, Low-Dose Naltrexone, Methylene Blue, Bioidentical Hormone Replacement Therapy (BHRT), and comprehensive detoxification programs. Highlights of the Discussion: Microdosing GLP-1 Receptor Agonists: Personalized medicine and its role in enhancing patient outcomes including microdosing. Sermorelin: Anti-aging protocols and the safe stimulation of growth hormone production. Low-Dose Naltrexone (LDN): Innovative uses in autoimmune diseases and chronic pain management. Methylene Blue: Emerging applications in neuroprotection and environmental detoxification. Bioidentical Hormone Replacement Therapy (BHRT): How personalized approaches differ from conventional treatments. Ask a pharmacist a question: TCCompound.com/contact
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Have you ever heard about Keto ABC Gummies? If not, you are missing out on one of the most exciting health trends in America right now. These gummies claim to be a breakthrough in weight loss and overall health management, and have even been featured on the hit TV show Shark Tank. With such high praise and attention, it’s no wonder that people are scrambling to get their hands on these powerful little gummies. But what exactly are Keto ABC Gummies, and do they live up to the hype? Let’s delve deeper into this innovative product and find out what makes them so special.
What are Keto ABC Gummies?
Keto ABC Gummies are a new and innovative way to support your ketogenic diet. Made with a unique blend of natural ingredients, these gummies are designed to help your body enter and stay in a state of ketosis. This means that your body will be burning fat for energy instead of carbohydrates, which can lead to rapid weight loss and improved overall health. Keto ABC Gummies are easy to incorporate into your daily routine and are a convenient way to support your keto lifestyle.
One of the key ingredients in Keto ABC Gummies is beta-hydroxybutyrate (BHB), which is a ketone that your body naturally produces during ketosis. By supplementing with BHB, you can help your body get into ketosis faster and stay there longer. This can lead to increased energy levels, improved mental clarity, and of course, weight loss. In addition to BHB, Keto ABC Gummies also contain other natural ingredients such as green tea extract, Garcinia Cambogia, and apple cider vinegar, all of which are known for their weight loss and health benefits.
How do Keto ABC Gummies work?
When you consume Keto ABC Gummies, the BHB in the gummies is quickly absorbed into your bloodstream. This signals your body to start burning fat for energy instead of carbohydrates, which can lead to rapid weight loss. In addition, the other natural ingredients in the gummies work together to support your overall health and well-being. Green tea extract is known for its metabolism-boosting properties, Garcinia Cambogia can help suppress your appetite, and apple cider vinegar has been shown to promote gut health.
By taking Keto ABC Gummies regularly, you can help your body stay in ketosis longer, which can lead to even greater weight loss and health benefits. These gummies are a convenient and delicious way to support your ketogenic diet and improve your overall health. If you have been struggling to lose weight or maintain a healthy lifestyle, Keto ABC Gummies may be the solution you have been looking for.
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If you are following a ketogenic diet or are interested in trying keto for weight loss or health reasons, Keto ABC Gummies could be a great addition to your daily routine. These gummies are easy to take and can help support your body’s natural fat-burning processes. However, it is important to remember that no supplement can replace a healthy diet and regular exercise. While Keto ABC Gummies can be a helpful tool in your weight loss journey, they should be used in conjunction with a healthy lifestyle for the best results.
Before starting any new supplement regimen, it is always a good idea to consult with your healthcare provider to make sure that the product is right for you. If you have any underlying health conditions or are taking medications, it is especially important to talk to your doctor before starting Keto ABC Gummies. With their blend of natural ingredients and powerful benefits, these gummies have the potential to support your health and weight loss goals, but it is always best to err on the side of caution when starting a new supplement.
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K1 Keto, a revolutionary weight-loss supplement, made its way onto the popular television show Shark Tank in hopes of securing a deal with one of the esteemed investors. The product, formulated with natural ingredients to boost metabolism and burn fat, has gained a lot of attention in the health and wellness industry. With the opportunity to showcase their product to a national audience, the creators of K1 Keto were eager to impress the sharks and potentially take their business to the next level.
The Pitch
As the K1 Keto team walked onto the set of Shark Tank, they were filled with a mix of nerves and excitement. The founders, a group of passionate individuals who had seen the positive effects of their product firsthand, were ready to share their story with the world. The pitch began with a brief introduction to the product and its benefits, followed by a demonstration of how K1 Keto works to support weight loss. The sharks listened intently, asking questions and expressing interest in the potential of the supplement.
One of the sharks, known for their tough negotiating tactics, pushed back on the founders, questioning the market potential and competitive landscape of the weight-loss industry. The K1 Keto team stood their ground, citing the positive feedback from customers and the unique selling points of their product. Despite the skepticism from some of the sharks, others saw the potential in K1 Keto and expressed interest in making a deal.
After some deliberation, the founders of K1 Keto received an offer from one of the sharks. The terms were negotiated, and a deal was struck that would provide the funding and expertise needed to take the business to the next level. The K1 Keto team left the tank feeling elated and hopeful for the future of their product.
The Aftermath
Following their appearance on Shark Tank, K1 Keto experienced a surge in sales and brand recognition. The exposure from the show helped to solidify their position in the market and attract new customers looking to achieve their weight-loss goals. The deal made with the shark investor provided the resources needed to scale up production and expand the reach of the product to a wider audience.
As K1 Keto continued to grow, they maintained their commitment to quality and customer satisfaction. The team worked tirelessly to improve the product and develop new offerings that would appeal to a diverse range of consumers. With the support of their investors, K1 Keto was able to navigate the challenges of building a successful business and establish itself as a trusted name in the health and wellness industry.
Over time, K1 Keto’s journey through Shark Tank became a symbol of perseverance and dedication in the face of adversity. The founders never gave up on their dream of bringing their product to the masses, and their hard work paid off in the form of a thriving business that continues to inspire others to pursue their passions.
Final Thoughts
As K1 Keto looks to the future, they remain focused on their mission to help people achieve their weight-loss goals in a healthy and sustainable way. The journey through Shark Tank was a pivotal moment in the company’s history, propelling them to new heights of success and recognition. With their innovative product and dedicated team, K1 Keto is poised to make a lasting impact on the health and wellness industry for years to come.
For those who may be considering starting their own business or pursuing a passion project, the story of K1 Keto serves as a reminder that anything is possible with hard work, determination, and a belief in the power of your ideas. The journey may not always be easy, but with perseverance and a willingness to adapt and grow, success is within reach.
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As K1 Keto continues to inspire others with their story of triumph and resilience, they stand as a testament to the power of entrepreneurship and the potential for innovative ideas to change lives for the better. The journey may have had its challenges, but the result is a thriving business that is making a difference in the lives of countless individuals seeking to improve their health and well-being.
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Did you know that some of your favorite franchise brands were born on Shark Tank? Well, it's true! Shark Tank has been the launchpad for many successful franchises you know and love today. Let's dive into the Shark Tank and discover some franchises that got their big break. Wicked Good Cupcakes - this mother-daughter duo, Tracey Noonan and Dani Vilagie, struck a sweet deal with Kevin O'Leary. Now, their Cupcake Jar Company is a nationally recognized brand. Cinnaholic - although co-founders Shannon and Florian didn't end up partnering with Robert Herjavec, their focus on brick and mortar locations really paid off. They've expanded across the US with their gourmet vegan cinnamon rolls. College Hunks Hauling Junk and Moving - founders Omar and Nick turned down a deal from Robert Herjavec, but they've continued to grow into a super successful franchise concept with 188 locations. So, which one of these surprise you the most? Don't forget to hit that like button and follow for more fun franchise facts. ◽️◽️◽️◽️◽️◽️ Want me to help you find the perfect franchise for you? Book a time here: https://calendly.com/macchia/discovery-call?month=2023-05 ◽️◽️◽️◽️◽️◽️ Instagram: https://www.instagram.com/franchisehounds TikTok: https://www.tiktok.com/@franchisehounds Twitter: https://twitter.com/FranchiseHounds #SharkTankFranchises #SuccessfulStartups #FranchiseSuccess
