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Calling all Body Detectives! 🕵️‍♀️🕵️‍♂️ Dr. Champ is back with another case, and this time, it's getting personal! 😉 We're diving deep into the world of sexual health, exploring solutions for premature ejaculation (PE) and erectile dysfunction (ED) that go beyond the little blue pill. (Are you looking for the secret history of the blue pill? Check out our history of medicine Body File -The secret story behind the little “blue pill” 🍆)” In this video, we'll uncover: -The truth about PDE5 inhibitors and how they REALLY work 💊 -Why "stop-start" training is OUT and daily tadalafil is IN for PE ⏱️ -How combination therapies can revolutionize your sex life 🚀 -The importance of advocating for your sexual health and finding the right treatment for YOU ❤️ Plus, Dr. Champ shares essential safety tips and reminds us that knowledge is power when it comes to sexual wellness. Don't miss this informative and empowering episode! Hit that like button 👍, subscribe to join the Body Detectives, and share this video with someone who needs to hear it! 😉 💋References: Dell'Atti L, Galosi AB, Ippolito C. A Randomized Single-Center Study to Compare the Efficacy and Tolerability of Tadalafil Once Daily Plus Lidocaine Anesthetic Spray on Premature Ejaculation. European Review for Medical and Pharmacological Sciences. 2017;21(5):1036-1040. Onal B, Can O, Ermec B, Culha MG. Retrospective Evaluation of the Efficacy of Daily Paroxetine/Tadalafil Combination in Patients With Premature Ejaculation and Erectile Dysfunction. European Review for Medical and Pharmacological Sciences. 2023;27(9):4248-4253. doi:10.26355/eurrev_202305_32335. Polat EC, Ozbek E, Otunctemur A, Ozcan L, Simsek A. Combination Therapy With Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors in the Treatment of Premature Ejaculation. Andrologia. 2015;47(5):487-92. doi:10.1111/and.12289. Abu El-Hamd M. Efficacy and Safety of Daily Use of Tadalafil in Treatment Of patients With Premature Ejaculation: A Randomised Placebo-Controlled Clinical Trial. Andrologia. 2018;50(5):e13005. doi:10.1111/and.13005. Mitsogiannis I, Dellis A, Papatsoris A, Moussa M. An Up-to-Date Overview of the Pharmacotherapeutic Options for Premature Ejaculation. Expert Opinion on Pharmacotherapy. 2022;23(9):1043-1050. doi:10.1080/14656566.2022.2035361 💋Hashtags: #ErectileDysfunction #ED #PrematureEjaculation #PE #SexualHealth #MensHealth #Tadalafil #Cialis #PDE5Inhibitors #SSRIs #Health #Wellness #DrChamp #BodyFiles #BodyDetectives #Science #Medicine #Education #Relationships #Intimacy #sildenafil #bluepill #doctor #health #healthylifestyle #mythbusting #wellness #erectiledysfunctiontreatment 💅🏻Disclaimer: The information provided in this video is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. While we strive to ensure the accuracy of the information presented, we cannot guarantee that it is complete, up-to-date, or error-free. Body Files and its creators are not liable for any damages or losses arising from the use of the information provided. 📚Medical professional huddle: Tadalafil is contraindicated in patients with certain cardiovascular conditions, those taking nitrates, and those with severe hepatic or renal impairment. Caution is also advised in patients predisposed to priapism or with a history of NAION. Combination therapy with SSRIs should be approached with caution due to the increased risk of adverse effects. Patients should be counseled on the interaction between tadalafil and alcohol. Both act as vasodilators, and substantial alcohol consumption can increase the risk of orthostatic hypotension, dizziness, and headache. It is important to remind patients that tadalafil does not protect against sexually transmitted diseases (STDs). Safe sexual practices should be encouraged and appropriate candidates should be offered PrEP.

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Learn how to increase testosterone in 5 easy ways and boost testosterone NATURALLY! Why is it important to maintain a healthy testosterone level? What is the significance of testosterone in the first place? I also tackle the mystery behind soybeans and Ashwagandha, an ancient medicinal herb. Do soybeans really lower testosterone levels? Does Ashwagandha have any real effects on testosterone? I discuss these topics (and more!) in detail, so make sure you stick around until the end! Thanks for watching!! Schedule an appointment: https://www.renamalikmd.com/appointments Become a premium member: https://renamalik.supercast.com Come back EVERY MONDAY for a NEW video Subscribe: https://www.youtube.com/c/RenaMalikMD/?sub_confirmation=1 Share this video with a friend: https://youtu.be/lef5duf6ylQ Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men: https://jamanetwork-com/journals/jama/fullarticle/1029127 Testosterone concentrations in young pubertal and post‐pubertal obese males https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cen.12018 Sleep timing may modulate the effect of sleep loss on testosterone https://doi.org/10.1111/j.1365-2265.2012.04419.x Impaired sleep is associated with low testosterone in US adult males: results from the National Health and Nutrition Examination Survey https://doi.org/10.1007/s00345-018-2485-2 An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract https://www-ncbi-nlm-nih-gov/pmc/articles/PMC6750292/ Soy protein intake by active young adult men raises plasma antioxidant capacity without altering plasma testosterone https://doi.org/10.1016/j.nutres.2005.12.002 Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: results of a meta-analysis https://pubmed.ncbi.nlm.nih.gov/19524224/ Serum Testosterone Concentrations and Urinary Bisphenol A, Benzophenone-3, Triclosan, and Paraben Levels in Male and Female Children and Adolescents: NHANES 2011–2012 https://ehp.niehs.nih.gov/doi/full/10.1289/EHP150 Increased physical activity has a greater effect than reduced energy intake on lifestyle modification-induced increases in testosterone https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706091/ ------------------------------------------------------ Check out these Playlists: Penis Problems?! Erectile Dysfunction, Premature Ejaculation & More: https://bit.ly/3wwivzS Overactive Bladder Treatment: https://bit.ly/3hMzBoP How to Increase Testosterone: https://bit.ly/2T9QJKV All my REACTION videos: https://youtu.be/_Dl46d7I1uI Reacting to Grey's Anatomy: https://youtu.be/LiDevzHnoos ------------------------------------------------------ DOWNLOAD YOUR LIST OF BLADDER IRRITANTS https://renamalikmd.com/bladder-irritants-landing-page/ ----------------------------------------------------- Check out my Amazon storefront (affiliate links included): https://www.amazon.com/shop/renamalikm.d. Coupons & Discount codes (affiliate links included): http://www.renamalikmd.com/linktree ----------------------------------------------------- Let's Connect!: WEBSITE: http://www.renamalikmd.com I INSTAGRAM: @RenaMalikMD http://www.instagram.com/RenaMalikMD TWITTER: @RenaMalikMD http://twitter.com/RenaMalikMD FACEBOOK: @RenaMalikMD https://www.facebook.com/drrenamalik/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ ------------------------------------------------------ DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.

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Semaglutide is a medication that has been gaining attention in recent years for its potential in aiding weight loss. Originally developed to treat type 2 diabetes, semaglutide has shown promising results in reducing body weight in patients who are overweight or obese. Researchers are now exploring the relationship between semaglutide and weight loss, with many hopeful that this could be a game-changer in the fight against obesity.

Understanding Semaglutide and Its Mechanism of Action

Semaglutide belongs to a class of medications called GLP-1 receptor agonists. GLP-1 (glucagon-like peptide-1) is a hormone that is naturally produced in the body and plays a role in regulating blood sugar levels and appetite. When semaglutide is injected, it mimics the action of GLP-1, leading to increased insulin secretion, reduced glucagon secretion, slowed gastric emptying, and increased feelings of fullness. This combination of effects can result in reduced food intake and ultimately weight loss.

Studies have shown that semaglutide can lead to significant weight loss in patients who are overweight or obese. In fact, in clinical trials, semaglutide has been shown to help individuals lose up to 15% of their body weight. This is a significant improvement compared to existing weight loss medications, which typically result in much smaller weight loss percentages. The effectiveness of semaglutide in promoting weight loss has led to its approval by the FDA for the treatment of obesity.

Potential Side Effects of Semaglutide

Like any medication, semaglutide is not without its potential side effects. Some common side effects of semaglutide include nausea, diarrhea, and constipation. These side effects are usually mild and tend to diminish over time as the body adjusts to the medication. However, in some cases, more serious side effects such as pancreatitis or thyroid tumors may occur. It is important for patients to discuss the potential risks and benefits of semaglutide with their healthcare provider before starting treatment.

It is also worth noting that semaglutide is not a magic bullet for weight loss. While it can be a helpful tool in achieving weight loss goals, it is most effective when combined with a healthy diet and regular exercise. Semaglutide should be used as part of a comprehensive weight loss program that includes lifestyle changes and behavioral therapy to ensure long-term success in maintaining weight loss.

Future Directions in Semaglutide Research

Researchers are continuing to study the effects of semaglutide on weight loss and are exploring new ways to optimize its use. Some studies are looking at the potential of combining semaglutide with other medications or therapies to enhance its weight loss effects. Others are investigating the long-term effects of semaglutide on weight maintenance and overall health. As research in this area progresses, we may gain a better understanding of how semaglutide can be used most effectively to combat obesity and improve patient outcomes.

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