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Novo Nordisk Invests 2 Billion In Promising Weightloss Drug

Gastrointestinal hormones called incretins such as Glucagon-like peptide-1 also known as GLP-1, lowers the blood sugar levels by stimulating the production of insulin when it is needed (for example after eating) and reducing the production of glucagon by the liver when it is not needed (for example during digestion). They also slow down digestion, decrease appetite and reduces weight. Based on these beneficial effects of Glucagon-like peptide-1, certain Glucagon-like peptide-1 receptor agonists, also known as GLP-1 receptor agonists or incretin mimetics, were developed for treatment of hyperglycemia in diabetic patients. Medications in these class includes, exenatide (trade names Byetta and Bydureon), liraglutide (trade names Victoza and Saxenda), lixisenatide (trade name Lyxumia), albiglutide (trade name Tanzeum), dulaglutide (trade name Trulicity) and Semaglutide. Semaglutide (trade name, Ozempic) is a medication developed by Danish company Novo Nordisk. Originally developed for the treatment of type 2 diabetes in 2012. Injection version of the drug has been approved by the US Food and Drug Administration (FDA) in 2017, and by the European Commission, Health Canada and the Japanese Ministry of Health, Labour and Welfare in 2018. On 20 Sep 2019, The U.S. Food and Drug Administration, approved Novo Nordisk's Rybelsus (containing semaglutide) oral tablets, to improve control of blood sugar in adult patients with type 2 diabetes, along with diet and exercise. The efficacy and safety of Rybelsus in reducing blood sugar in patients with type 2 diabetes were studied in several clinical trials, two of which were placebo-controlled and several of which were compared to other GLP-1 injection treatments. Rybelsus was studied as a stand-alone therapy and in combination with other diabetes treatments, including metformin, sulfonylureas (insulin secretagogues), sodium-glucose co-transporter-2 (SGLT-2) inhibitors, insulins and thiazolidinediones, all in patients with type 2 diabetes. In the placebo-controlled studies, Rybelsus as a stand-alone therapy resulted in a significant reduction in blood sugar (hemoglobin A1c) compared with placebo, as determined through HbA1c tests, which measure average levels of blood sugar over time. Recommended dose of Rybelsus: Rybelsus can be started with 3 mg once daily for 30 days. After 30 days on the 3 mg dose, it can be increased to 7 mg once daily. Dose may be increased to 14 mg once daily if additional glycemic control is needed after at least 30 days on the 7 mg dose. It is not recommended as first-line therapy for patients inadequately controlled on diet and exercise and Not indicated for use in patients with type 1 diabetes mellitus or treatment of diabetic ketoacidosis. Adverse reactions and Contraindications: The most common adverse reactions, reported in patients treated with Semaglutide are gastrointestinal side effects including nausea, abdominal pain, diarrhea, decreased appetite, vomiting and constipation. Thyroid c-cell tumors. Pancreatitis. Diabetic Retinopathy Complications. Hypoglycemia. Acute Kidney Injury. Hypersensitivity Reactions. Thank You for watching this video. Please like, subscribe, share and hit the bell icon for more such videos. Please visit my blog at: http://www.medicalinfo4u.com/ Please check out my other videos below: FDA new drug approvals for treatment of hypotension (Biorphen), AHUS (Ravulizumab), cystic fibrosis: https://youtu.be/gS-fY71ddgU FDA approves Xeris’s Gvoke (glucagon pen) to treat severe hypoglycemia in diabetes patients: https://youtu.be/zy2LK91vq90 FDA approves nasal glucagon for treatment of severe hypoglycemia: https://youtu.be/kLfIKCcHtpU SGLT2 inhibitors: Do you know about this new diabetes medications? https://youtu.be/EtNM0dX36c8 6 MAJOR LONG TERM COMPLICATIONS OF DIABETES: https://youtu.be/6Yfrr9L6tCk Side effects of steroids: https://youtu.be/iEagfQUQs8E #MedicalInfo4U #FDAapprovedmedicine #newmedicine #Rybelsus #Gvoke #NovoNordisk #GLP1agonists

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Get a free 2 week trial of MacroFactor here: http://bit.ly/jeffmacrofactor In this video I'm breaking down several potential strategies for "boosting metabolism". We'll discuss drinking more water, green tea, spicy foods, sauna, ice baths, reverse dieting, meal frequency, weighted vests, gaining muscle mass, and cardio. Along the way, we will categorize these based on if they “work”, “might work”, or “probably don't work”. ------------------------------- ** My Fundamentals Training Program: https://shop.jeffnippard.com/product/fundamentals-hypertrophy-program/ ** MacroFactor Diet App: http://bit.ly/jeffmacrofactor [FREE 2 week trial] ** My Ultimate Guide To Body Recomposition: https://shop.jeffnippard.com/product/the-ultimate-guide-to-body-recomposition/ ** MASS (Monthly Research Review): https://bit.ly/jeffMASS ** Rise Gym Apparel: https://rise.ca/jeff ** PEScience Supplements: https://www.PEScience.com/discount/jeff ** Instagram: https://instagram.com/jeffnippard ------------------------------- Categories: 0:00 - Intro 0:42 - What is metabolism? 2:47 - Drinking more water 3:58 - Green tea 4:39 - Spicy food (capsaicin) 5:47 - Sauna 6:18 - Ice baths 6:50 - Building muscle 7:43 - Reverse dieting 8:41 - Meal frequency 9:33 - Cardio 10:49 - Weighted vests 11:53 - Slow dieting 12:15 - NEAT smuggling 12:35 - Weight loss success ------------------------------- References: Variability in Daily Energy Expenditure: https://pubmed.ncbi.nlm.nih.gov/34385400/ Green Tea: https://pubmed.ncbi.nlm.nih.gov/33671139/ https://pubmed.ncbi.nlm.nih.gov/17906192/ https://pubmed.ncbi.nlm.nih.gov/10584049/ https://pubmed.ncbi.nlm.nih.gov/19445822/ https://pubmed.ncbi.nlm.nih.gov/20372175/ https://pubmed.ncbi.nlm.nih.gov/25740906/ https://pubmed.ncbi.nlm.nih.gov/24299662/ Spicy Foods: https://pubmed.ncbi.nlm.nih.gov/28001433/ Sauna: https://pubmed.ncbi.nlm.nih.gov/7743620/ Ice Baths: https://pubmed.ncbi.nlm.nih.gov/10751106/ Reverse Dieting: https://macrofactorapp.com/reverse-dieting/ Meal Frequency: https://pubmed.ncbi.nlm.nih.gov/22719910/ https://pubmed.ncbi.nlm.nih.gov/26024494/ Weighted Vest: https://pubmed.ncbi.nlm.nih.gov/29279372/ https://weightology.net/the-use-of-weighted-apparel-during-contest-prep/ Energy Expenditure and Weight Loss Success: https://pubmed.ncbi.nlm.nih.gov/35013190/ ------------------------------- Filmed by Matt Dziadecki https://www.instagram.com/dziadecki/ Edited by Jeff Nippard Music by Bankrupt Beats: https://www.youtube.com/watch?v=xUCZTjMJr2k ------------------------------- About me: I'm a Canadian natural pro bodybuilder and internationally-qualified powerlifter with a BSc in biochemistry/chemistry and a passion for science. I've been training for 15 years drug-free. I'm 5'5 and fluctuate between 160 lbs (lean) and 180 lbs (bulked). ------------------------------- Disclaimers: Jeff Nippard is not a doctor or a medical professional. Always consult a physician before starting any exercise program. Use of this information is strictly at your own risk. Jeff Nippard will not assume any liability for direct or indirect losses or damages that may result from the use of information contained in this video including but not limited to economic loss, injury, illness or death.

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Today we have a 20 minute fat burning wall Pilates workout. This intense low impact workout will tone your whole body, build strength as well as burn fat! Access ALL programs & challenges to 10x your results - https://www.jennacollinsfitness.com/plans-pricing 8 Week Wall Pilates Ultimate Body Sculpt - https://www.jennacollinsfitness.com/8-week-wall-pilates-program 21 Day Weight Loss Accelerator - https://www.jennacollinsfitness.com/21-day-weight-loss-program 7 Day Belly Fat Breakthrough (Free) - https://www.jennacollinsfitness.com/7daybellyfatbreakthrough Instagram - https://www.instagram.com/jennacollinsfitness/ Website - www.jennacollinsfitness.com Business email - [email protected] General disclaimer Any form of exercise involves a risk of injury, especially when performed incorrectly or with poor form. I am a qualified personal trainer and nutrition coach. I am not a physician, dietitian or medical doctor. Please do not take my advice as a substitute for medical advice. The health and fitness advice provided on my channel is to the best of my knowledge and is a guideline for exercise and nutrition that you can follow and perform at your own risk. Should you have any existing medical conditions or health concerns please consult a medical doctor before performing any exercises or implementing nutritional advice provided Jenna Collins Fitness. I do not guarantee results from any of my workouts. Each person is different and will get different results from any workout they perform. Regular exercise combined consistent good nutrition habits is key to getting results.

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💊 Is Ozempic really a miracle weight loss drug, or is there more to the story? From social media buzz to lawsuits and side effects, the Ozempic controversy is heating up! In this video, we uncover the truth behind the hype, the risks, and what experts are saying. ✅ Why Ozempic is so controversial right now ✅ The biggest concerns about Ozempic for weight loss ✅ What doctors are saying about long-term risks ✅ Lawsuits, side effects, and public backlash explained ✅ Should you take Ozempic? Expert recommendations 💡 Is the Ozempic controversy justified, or is it overblown? Watch till the end for the real truth! 👉 What do you think about the Ozempic controversy? Drop your thoughts in the comments! 🔔 Subscribe for more health & pharmacy updates! 👍 Like & Share to spread awareness! #Ozempic #OzempicControversy #WeightLossDrug #OzempicExposed #OzempicSideEffects #WeightLossDebate #PharmacyAdvice #GLP1Medication #HealthNews #OzempicScandal "What do you think about the Ozempic controversy? Do you believe it’s overhyped or a real concern? Share your thoughts below!" 📢 Subscribe for more health & pharmacy tips! → https://www.youtube.com/@PharmacistOnline?sub_confirmation=1 ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ 🎬SUGGESTED VIDEOS Don't forget to watch other videos. Please check them out : https://youtu.be/AMNlkvd4krY https://youtu.be/7dKyUA3FXO4 https://youtu.be/j5Qg2gDIENg https://youtu.be/3QJgXkRmB5k Disclaimer Fair Use: 1. The videos have no negative impact on the original works. 2. The videos we make are used for educational purposes. 4. We use only the audio component and tiny pieces of video footage, only if it's necessary. DISCLAIMER: Copyright Disclaimer Under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education, and research. Fair use is permitted by copyright statutes that might otherwise be infringing.

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