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#diabetes #weightloss #antihungermedicine Weight loss by diabetes drug linked to "anti-hunger" molecule, finds study Researchers from Stanford Medicine and Harvard Medical School have discovered an “anti-hunger” molecule that is produced after vigorous exercise is responsible for the moderate weight loss caused by the diabetes medication metformin. The finding published in the journal Nature Metabolism revealed the critical role the molecule, called lac-phe, plays in metabolism, exercise and appetite which may help to discover a new class of weight loss drugs. Many people with diabetes who are prescribed metformin lose around 2% to 3% of their body weight within the first year of starting the drug. Although this amount of weight loss is modest when compared with the 15% or more often seen by people taking semaglutide drugs, the discoveries that led to those drugs also grew from observations of relatively minor, but reproducible, weight loss in people taking first-generation versions of the medications. “Until now, the way metformin, which is prescribed to control blood sugar levels, also brings about weight loss has been unclear,” said Jonathan Long, PhD, an assistant professor of pathology. “Now we know that it is acting through the same pathway as vigorous exercise to reduce hunger. Understanding how these pathways are controlled may lead to viable strategies to lower body mass and improve health in millions of people.” The researchers observed obese laboratory mice who were given metformin and found increased levels of lac-phe in their blood. They ate less than their peers and lost about 2 grams of body weight during the nine-day experiment. In the study, Long and colleagues analyzed blood plasma samples from people with Type 2 diabetes before and 12 weeks after starting metformin treatment. They found significant increases in lac-phe levels post-metformin. Additionally, among 79 participants in a multi-ethnic atherosclerosis study taking metformin, those on the drug had higher circulating lac-phe levels compared to non-users. Moreover, a statistical analysis of individuals in the atherosclerosis study who experienced weight loss over the study and follow-up period revealed a significant connection between metformin usage, lac-phe production, and weight reduction. “It was nice to confirm our hunch experimentally. The magnitude of effect of metformin on lac-phe production in mice was as great as or greater than what we previously observed with exercise. If you give a mouse metformin at levels comparable to what we prescribe for humans, their lac-phe levels go through the roof and stay high for many hours.” said Long. “These findings suggest there may be a way to optimize oral medications to affect these hunger and energy balance pathways to control body weight, cholesterol and blood pressure. I think what we’re seeing now is just the beginning of new types of weight loss drugs.” Check full updates on Medical Dialogues Also check out - Medical Dialogues Academy, a renowned academic wing of Medical Dialogues - India's premier health and news online portal, proudly presents this comprehensive course tailored for healthcare professionals eager to delve into the realm of medical journalism. 🔗 Enroll Today: https://academy.medicaldialogues.in/courses/certificate-course-in-medical-journalism/ 📚 Explore More With Us: 📌 Medical Content Writing: https://academy.medicaldialogues.in/courses/medical-content-writing/ 📌 Certificate Course in Pharmaceutical Medico-Marketing: https://academy.medicaldialogues.in/courses/certificate-course-in-pharmaceutical-medico-marketing/ Join us on this enlightening journey and become a part of a community pushing the boundaries of healthcare communication and reporting. Get the latest medical and health news at medicaldialogues.in Follow us on Twitter: https://twitter.com/medicaldialogs Facebook: https://www.facebook.com/medicaldialogues/ Instagram: https://www.instagram.com/medicaldialogues LinkedIn: https://www.linkedin.com/company/medical-dialogues Website: https://medicaldialogues.in/

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Recently, a weight loss solution called Shark Tank Diet Keto has invaded the markets. Several people have claimed they have lost weight with it. However, the legitimacy and viability of this diet has been brought into question by some physicians and the general public. In this essay, we delve into Shark Tank Diet Keto, debating its effectiveness, whether it is healthy for weight loss and if it’s a lasting weight loss solution. Over the years, various weight loss solutions have been proposed. The internet is filled with information on weight loss, a search on Google only highlights the abundance of matters surrounding weight loss and the various ways of achieving it. In my opinion, Shark Tank Diet Keto is just but one of the several solutions that have been marketed over time. The desire to lose weight remains a constant point of discussion between men and women. To me, Shark Tank Diet Keto acts as a stimulant or turning point for many people.

Understanding the Shark Tank Diet Keto

Shark Tank’s ‘reinvented diet’ sounds like a high-fat, low-carb eating plan, deliberately eaten in a way that triggers ketosis, a metabolic state in which the brain and body converts fat, not carbohydrates, into fuel. Ketosis does this by bypassing carbohydrates as an energy source, relying instead on body fat for fuel. Ketogenic diets can be effective methods for weight loss because, in ketosis, energy is primarily derived from fat burning (instead of glucose as in nonketosis), resulting in a body fat percentage that decreases.

Furthermore, according to the website for the Shark Tank Diet Keto, theirs is a diet that will help their customers ‘lose weight quickly’, ‘increase energy’, ‘boost brain function’ and ‘reduce inflammation’. Foods are similar to the foods prescribed by other Keto followers: meats, fish, eggs, nuts, seeds and low-carb vegetables are fair game, while avoiding grains, fruits and sugar is advised.

Yet defenders of the Shark Tank Diet Keto point out that a VLCKD can be unsustainable in the long term, and suggest that failing to follow the diet’s strict nutrient recommendations for good health can result in nutrient deficiencies. They are also concerned about the lasting effects a high-fat diet could have on cholesterol levels and cardiovascular health. Furthermore, they point out that there’s no evidence that the diet is safe for long-term use, though there’s a limited body of evidence that it may be safe and effective for six months.

Evaluating the Impact of the Shark Tank Diet Keto

Some Shark Tank Diet Keto consumers believe they’ve lost weight and improved their health, but eating keto is no guarantee of that. While it has been helpful to some obese people in overcoming type-2 diabetes and other obesity-related disorders, it can exacerbate certain conditions such as gallstones, kidney stones, fatty liver disease, and pancreatitis.

While all these success stories are heartening and encouraging anecdotes, it’s also important to take a larger look at the prospective pitfalls and risks of the diet: some individuals will likely experience side effects, including fatigue, constipation, bad breath or simply finding it challenging or uncomfortable to keep up with the diet indefinitely, which could result in subsequent weight gain should they choose to revert to their previous eating habits.

However, \( Shark \: Tank \: Diet \: Keto \) could also be unsafe for some and isn’t appropriate for everyone, especially those with medical conditions or dietary restrictions. Speak with your healthcare provider or registered dietitian before trying any new nutrition regimen to ensure it’s right and healthy for you.

Debunking Common Myths About the Shark Tank Diet Keto

Many of his victims have issues wading through the falsehoods that surround the Shark Tank Diet Keto, keeping them from learning the truth about the diet’s real effects and veracity. One such misconception is that everyone can lose weight with the diet and, in as little as a week, drop a slew of pounds simply by following it.

But in truth, the Shark Tank Diet Keto requires a commitment to rigorously follow a restricted diet and count macronutrients to reach and sustain a state of ketosis, and is not a one-size-fits-all strategy for weight loss. It is also not a diet that allows for much flexibility or variance in the eating style.

A second myth is that the ketogenic diet (and variations like the Shark Tank Diet Keto) allows you to get lean permanently through diet alone, without regular exercise or deliberate, thoughtful feeding behaviours. The diet can be effective to kickstart weight loss and ameliorate metabolic health, but you will always need physical activity and a balanced diet to sustain it.

Conclusion: Is the Shark Tank Diet Keto Legitimate?

In the end, whether the Shark Tank Diet Keto is a good framework to lose weight hinges upon the goals and personal preferences and tolerance of the dieter, as well as underlying medical histories. For some, it can be the key to setting a health-bolstering weight-loss plan in motion. Others, however, may have difficulty keeping their bodies in ketosis, or struggle with eating consciously while abiding by a diet entailing restrictive foods and macronutrient ratios, or even experience negative manifestations.

Please note: Research the Shark Tank Diet Keto, any other weight loss program or diet carefully before you start it, do not forget to consult with your health care professional on the suitability of the chosen diet or weight loss program as it relates to your unique health needs and preferences. Sustainable weight loss requires a balanced healthy diet, regular physical activity, and healthy lifestyle. This is far more effective than any quick-fix diet pill, fasting trick, or ‘miracle’ app promising instant weight loss.

In conclusion, the Shark Tank Diet Keto could be a good starting point for some people looking to lose weight and transform their wellbeing – but this diet requires thoughtful consideration, especially in terms of sustainability and its potential side effects. By making thoughtful decisions and placing your health as a priority, you can have an effective and continual weight loss experience.

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