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(USMLE topics) Methamphetamine: mechanism of action, short-term and long-term effects, addiction and overdose. Purchase a license to download a non-watermarked copy of this video on AlilaMedicalMedia(dot)com ©Alila Medical Media. All rights reserved. Voice by: Ashley Fleming All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Methamphetamine, also called meth or crystal meth, among other names, is a psychostimulant drug mainly known for its recreational use. Methamphetamine is chemically similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder, obesity and narcolepsy; but being more potent and highly addictive, methamphetamine is rarely prescribed for medical treatments. Most commonly, the drug is produced illegally, from pseudoephedrine, an ingredient in cold medicines. It can exist as white powder, pills, or bluish-white crystals, and can be consumed by swallowing, smoking, snorting, or injecting. Methamphetamine acts to increase the amount of a neurotransmitter called dopamine in the brain. Dopamine is at the basis of the brain reward pathway, which is designed to “reward” the body for important behaviors that are essential for survival, such as feeding when hungry. Engaging in enjoyable activities causes dopamine release from dopamine-producing neurons into a space between neurons, where it binds to and stimulates its receptors on the neighboring neuron. This stimulation is believed to produce pleasurable feelings or rewarding effect. Normally, dopamine molecules are promptly cleared from the synaptic space to ensure that the postsynaptic neurons are not over-stimulated. This is possible thanks to the action of dopamine-transporter, which channels dopamine back to the transmitting neuron. Methamphetamine binds to dopamine-transporter and blocks dopamine re-uptake. In addition, it can enter the transmitting neuron and trigger more dopamine release. The result is that dopamine builds-up in the synapse to a much greater amount than normal. This produces a continuous over-stimulation of receiving neurons and is responsible for the prolonged and intense euphoria experienced by drug users. At a low dose, methamphetamine stimulates the brain and can elevate mood and alertness; and by accelerating heart rate and breathing rate, it increases energy in fatigued individuals. It also reduces appetite and promotes weight loss. These seemingly “positive” effects keep users coming back for more, eventually leading to addiction and potential overdose. Long-term drug users may experience extreme weight loss, severe dental damage, and constant hyperactivity which results in anxiety, sleeping disorders and violent behaviors. Overdose takes the drug’s effects to the extreme and can cause psychosis, heart attacks, seizures, strokes, organ failures, and even death. Currently, there is no approved pharmacological treatment for methamphetamine addiction; the most effective treatments are cognitive behavioral therapies.

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When it comes to CBD gummies, there is a lot of buzz about their potential health benefits, from helping with anxiety and pain relief to improving sleep and mood. But can these tasty treats also aid in treating erectile dysfunction (ED) and promoting weight loss? In this article, we will delve into a dual-purpose investigation to explore the potential effects of CBD gummies on these two common health concerns.

The Potential of CBD Gummies for Treating ED

Erectile dysfunction is a common condition that affects millions of men worldwide, impacting their ability to achieve or maintain an erection. While there are various treatment options available, some individuals are turning to alternative remedies like CBD gummies. CBD, or cannabidiol, is a compound found in cannabis and hemp plants that has been shown to have anti-inflammatory and analgesic properties. These properties may potentially help improve blood flow and alleviate anxiety, both of which can contribute to ED.

Research on the effects of CBD on ED is still limited, but some studies have shown promising results. For example, a study published in the Journal of Sexual Medicine found that CBD may help increase blood flow to the pelvic area, which could improve erectile function. Additionally, CBD’s calming effects may help reduce performance anxiety, a common psychological cause of ED.

It’s essential to note that more research is needed to fully understand the benefits of CBD gummies for treating ED. It’s always best to consult with a healthcare provider before incorporating CBD into your treatment regimen, especially if you are taking medications for ED or other health conditions.

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The Role of CBD Gummies in Weight Loss

Weight loss is another common health goal for many individuals, and CBD gummies are being touted as a potential aid in achieving this objective. While CBD itself is not a weight loss miracle, it may indirectly support weight loss efforts through various mechanisms. For example, CBD has been shown to help regulate metabolism, reduce appetite, and promote fat browning, which converts white fat cells into brown fat cells that are easier to burn.

Additionally, CBD gummies may help reduce inflammation in the body, which can contribute to weight gain and make it challenging to lose weight. Chronic inflammation has been linked to obesity and metabolic disorders, so reducing inflammation with CBD could potentially support weight loss efforts.

It’s important to remember that CBD gummies are not a substitute for a healthy diet and regular exercise when it comes to weight loss. While they may offer some support, it’s crucial to focus on overall lifestyle habits to achieve and maintain a healthy weight.

FAQs about CBD Gummies for ED and Weight Loss

Q: Are CBD gummies safe to use for treating ED and promoting weight loss?

A: CBD is generally considered safe for most people, but it’s always best to consult with a healthcare provider before using CBD gummies, especially if you have underlying health conditions or are taking medications.

Q: How long does it take to see results from using CBD gummies for ED or weight loss?

A: The effects of CBD gummies can vary from person to person, so it may take some time to see noticeable results. It’s essential to be patient and consistent with your use of CBD gummies for optimal outcomes.

Q: Can CBD gummies interact with medications for ED or weight loss?

A: CBD has the potential to interact with certain medications, so it’s essential to talk to your healthcare provider before using CBD gummies alongside any prescription medications for ED or weight loss.

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