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This week on Obesity Updates, Ascletis begins a U.S. Phase 2a trial of ASC30, a once-monthly oral GLP-1 agonist, while Viking launches its Phase 3 VANQUISH trial for VK2735. Viatris clears a key legal hurdle, paving the way for generic Wegovy. Roche discontinues CT-173 but shifts focus to CT-388 after promising Phase 1b data. Finally, a global study projects universal GLP-1 access could cut obesity rates by 52% and save 37 million lives—highlighting urgent policy and access gaps in obesity care.

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This would have to be one of the most asked questions we get, especially for the gym junkie who wants to get that elusive tone in their abs or legs. This video we share with you the secrets to finding the answers to this question. And this is not what you would expect. For many it is about calories, but what I explain in this short video is that calorie counting is a waste of time and it really comes down to 3 things Reduce your stress Eat quality nutrition and eat frequently Add muscle using functional strength training techniques If you do these 3 things and in this order you will achieve optimal health, happiness and lose fat without losing muscle. This is without doubt the most frustrating thing I have come across in my career as a Personal Trainer in Melbourne. The client who absolutely hammers themselves with all types of exercise, but has poor nutrition habits and wonders why they don't lose the belly fat! A classic case of the gym junkie who is ignorant to the two biggest factors regarding weight loss, STRESS and NUTRITION. In fact it is also safe to say that most personal trainers are ignorant to the first factor too! What you’ll see here is two things happening. Firstly whenever cortisol levels (your stress hormones) are chronically high, it suppresses your androgens (growth hormones), so things like testosterone and growth hormone are suppressed, which is not good if you are trying to add muscle to get stronger and fitter. You need more muscle to speed up your metabolism so you are already off to a bad start. In addition to testosterone decreasing, your gluco-corticoids or your stress hormones are elevated. One of the first reactions is that the body thinks that it’s going to have a long-term energy crisis, if we repeatedly stress out our hormonal system. So what normally happens is most bodies will start accumulating fat right around the belly button, and this is your signal that this is a chronic stress related problem. Make sure you watch this video to fully understand What Stress Is and Where Does it come from. So what do most people do to get rid of the gut? They start doing heaps of ab exercises, do more boxing classes or run more, and start starving themselves or cutting fat out and sorts of other crazy and ineffective ideas. This is the go hard go home mentality that does not work, and will only set you up for a lifetime of chronic problems. By the way calorie restriction never works either in case you were thinking of doing that too. Another philosophy of most personal trainers and diet books that just sets people up for....... you guessed it, more STRESS! What you need to do is, Eat high quality meals balanced for your Metabolic Type, Reduce your stress. Watch the video on Reducing Stress for ideas on how to do this Lastly NEVER skip meals or go longer than 4 hours without eating and you’ll see that that fat around the belly button will start to metabolize and disappear which makes everybody happy. Include a good Strength training program 3-4 times per week. (If you need help designing a program go to our Personal Training page and fill in a consult form and I will get in touch with you within 24 hours) If you live in Melbourne make sure you go to our website and fill in a contact form to book a free health and fitness consultation. https://www.noregretspt.com.au/index.php/specialised-programs/weight-loss-plans

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In the fast-paced world of healthcare, a new player has arrived in the fight against obesity—Wegovy. But is it just another medication, or could it be a real game-changer? Unlike traditional weight loss treatments, Wegovy isn’t just about willpower—it’s designed to alter the way the body regulates weight. With obesity being one of the most pressing public health challenges today, the arrival of new medical solutions could mean a breakthrough for millions. But how does it really work? And is it as effective as people claim? Let’s break it all down in this episode.

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Show Notes: https://www.jayfeldmanwellness.com/eb-134-the-sugar-diet-lose-fat-and-increase-your-metabolism-without-losing-muscle-mass Free Energy Balance Mini-Course: https://www.jayfeldmanwellness.com/energy/ Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide Energy Balance Solution program: https://jayfeldmanwellness.com/solution Jay's Instagram: https://www.instagram.com/jfwellness/ Jay's Facebook: https://www.facebook.com/jayfeldmanwellness/ Jay's Website: https://jayfeldmanwellness.com/ In this episode we discuss: -How the sugar diet, honey diet, and other similar diets actually work and whether FGF21 is really responsible for their benefits -How you can lose weight while eating sugar and without sacrificing your health -The side-effects of the sugar diet and how to modify the diet to prevent those effects -The surprising effects of the sugar diet on testosterone, digestion, and bone health -Whether you’ll lose muscle on a low protein diet like the sugar diet -Whether you shouldn’t be eating carbs and fats together due to the Randle cycle 0:00 – intro 1:08 – FGF21 summary: increasing metabolism at a cost 4:06 – how the sugar diet, honey diet, fruit till noon diet, fairy princess diet, and other similar diets actually work 10:03 – low-fat diets improve insulin sensitivity, even without protein restriction or FGF21 upregulation 17:50 – whether very low protein diets are ever beneficial and whether they always lead to muscle loss 25:54 – protein recommendations for insulin sensitivity, weight loss, and kidney function 29:07 – using the sugar diet for rapid weight loss or “getting shredded” 32:13 – sugar diet concerns: bone loss, infertility, stunted growth, muscle loss, metabolic suppression, weight regain, and nutrient deficiencies 35:53 – will eating protein with dinner prevent the negative effects? 36:28 – blood sugar instability, sleep issues, and excess glucagon on the honey diet and sugar diet 40:17 – Randle Cycle misconceptions: do you need to separate carbs and fats 44:50 – how low-fat diets work to improve glucose metabolism and misapplications of the Randle cycle 48:17 – low-fat diets and hormones: low testosterone and DHT levels in men 49:22 – the sugar diet and digestion: SIBO, impaired liver detoxification, low bile flow, and endotoxin 53:52 – is the sugar diet too restrictive? Is it sustainable? 59:57 – how to modify the sugar diet to reduce the negative effects 1:02:23 – how to achieve lasting weight loss while improving long-term health ​​To take a look at the studies and articles referenced throughout this episode, check out the show notes at https://www.jayfeldmanwellness.com/eb-134-the-sugar-diet-lose-fat-and-increase-your-metabolism-without-losing-muscle-mass Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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