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PMDD stands for premenstrual dysphoric disorder. This is not to be confused with Premenstrual Syndrome or PMS. PMS is changes in mood during certain parts of the menstrual cycle. It affects 80% of women. The mood changes can be mild to moderate. In fact, some women will just see it as feeling a little moody the week before their menstrual cycle. PMDD is a severe form of PMS. It’s almost like turning into the werewolf when the full moon rises. For some people, it’s just that drastic. It affects 3% - 8% of women. So it’s not as common as PMS. We treat PMDD with antidepressants or hormone therapy. I show you why some women get PMDD and why the antidepressants help. I discuss the difference between intermittent and continuous dosing with antidepressants. I also discuss the two main hormone treatments. If you do not want to take any kind of medication, you can try lifestyle changes. The first are diet modifications such as eliminating caffeine, sugar, nicotine and alcohol and minimizing sodium. You would combine this with sleeping 7-9 hours a night and getting regular exercise – like 3-5 times a week. Some nutritional supplements have shown to be helpful. These would be Calcium 1200mg/day, Vitamin B6 50-100mg/day. Other supplements would be Magnesium 200 – 360mg/day, Vitamin E 400 IU/day. There are some herbal remedies that have been shown in studies to be helpful. Agnus castus fruit extract, also known as chasteberry and Gingko biloba. To download the mood diary go here: http://markspsychiatry.com/mood-diary/ Video on Brain Zaps from medication withdrawal http://www.youtube.com/watch?v=KrcUEarpx-s Want to know more about mental health and self-improvement? On this channel I discuss topics such as bipolar disorder, depression, anxiety disorders, attention deficit disorder (ADHD), relationships and personal development/self-improvement. If you don’t want to miss a video, click here to subscribe. https://goo.gl/DFfT33 References: Article about how SSRI’s increase allopregnalone Griffin LD, Mellon SH. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23):13512–13517. Bäckström T, Bixo M, et. al. Allopregnanolone and mood disorders. Prog Neurobiol. 2014 Feb; 113:88-94. Epub 2013 Aug 23. Schiller CE, Schmidt PJ, Rubinow DR. Allopregnanolone as a mediator of affective switching in reproductive mood disorders. Psychopharmacology (Berl). 2014;231(17):3557–3567. doi:10.1007/s00213-014-3599-x Griffin LD, Mellon SH. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23):13512–13517. Khine K, Rosenstein DL, Elin RJ, Niemela JE, Schmidt PJ, Rubinow DR. Magnesium (Mg) retention and mood effects after intravenous Mg infusion in premenstrual dysphoric disorder. Biol Psychiatry. 2006 Feb 15;59(4):327-33. Yonkers KA, Pearlstein TB, Gotman N. A pilot study to compare fluoxetine, calcium, and placebo in the treatment of premenstrual syndrome. J Clin Psychopharmacol. 2013 Oct; 33(5):614-20. Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.

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Let's deep dive into whether you should lose body fat or build lean muscle first. This can often be a confusing topic so i wanted to make it easy and understandable so you can then hopefully make your decision. I'll be showing you the best ways to do both and really see results from each phase. Also check out my free calorie calculator (which makes more sense after watching the video) It'll give you a good idea on what calories you need for either losing body fat or gaining lean muscle! https://matthewdowningcoaching.com/calculator-lifestyle-assessment/ I hope you enjoy the video and get something from it! If you have any subjects you'd like me to go over then please leave them in the comments below!

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The popular weight loss “miracle” drug, Ozempic, has been a topic of much debate and curiosity amongst Americans. With obesity hitting record heights and highly influential people, doctors, and celebrities singing its praises, it makes sense why people would be curious. Like most “quick fixes,” however, Ozempic is no magic bullet. While it holds great potential as a weight loss tool, there’s a knowledge gap that remains to be addressed about its proper usage and discontinuation among individuals. Today on The Dhru Purohit Podcast, we have a special compilation episode where Dhru speaks with several past podcast guests about the pros, cons, and best practices for taking Ozempic and other GLP-1 agonists. Dhru sits down with JJ Virgin to get her nuanced take on where these weight loss drugs might benefit those battling lifelong obesity and metabolic disorders. He speaks with Calley Means to get his insights on how these drugs are approved, the dirty tactics behind their marketing, and the agenda behind their streamlined FDA approval for obese teens. In a sneak peek of his upcoming episode, Dhru asks Dr. Gabrielle Lyon about what she’s seen in her clients taking Ozempic, the importance of resistance training and monitoring protein intake on these weight loss drugs, and potential side effects. Finally, Dhru highlights an interview with his wellness colleagues, Dr. Casey Means and Dr. Robert Lustig, on how to use Ozempic correctly and strategies to get off it safely. In this special compilation episode, Dhru dives into: -Why we’re talking about Ozempic and GLP-1 weight loss drugs -JJ Virgin’s nuanced thoughts on Ozempic -The importance of a healthy diet and lifestyle as an adjunct to Ozempic -Calley Mean’s criticism of Ozempic as a long-term solution to the obesity crisis -Financial corruption within the institutions funding weight loss drugs -Metabolic and comorbidity cost of Ozempic in teens -Dr. Gabrielle Lyon breaks down the best and worst practices around Ozempic -Side effects of Ozempic and other GLP-1 agonists -Dr. Casey Means and Dr. Robert Lustig on how to take GLP-1 agonists the right way -How to come off of them successfully -Evidence-based ways for sustainable weight loss in children Also mentioned in this episode: -The Top Weight Loss Do’s and Don'ts for Women 40+ with JJ Virgin (episode 407): https://podcasts.apple.com/us/podcast/dhru-purohit-podcast/id1381257272?i=1000619114815 -Whistleblower Exposes the Dirty Tactics that Coca-Cola Used to Rig the System and Keep Vulnerable Populations Unhealthy with Calley Means (episode 363): https://podcasts.apple.com/us/podcast/dhru-purohit-podcast/id1381257272?i=1000595414392 -How Does GLP 1 & Ozempic Affect Metabolic Health & Do They Work? | Dr. Rob Lustig & Dr. Casey Means: https://www.youtube.com/watch?v=AKNnxKAaONc -A Whole New Level - Levels’ podcast: https://podcasts.apple.com/us/podcast/levels-a-whole-new-level/id1563263076 -Well Beyond 40 - JJ Virgin’s podcast: https://podcasts.apple.com/us/podcast/well-beyond-40/id911502027 This episode is brought to you by: -Birch Living: https://birchliving.com/dhru -Pique Life: https://piquelife.com/dhru To get 20% off your Birch Living mattress, head over to https://birchliving.com/dhru today. For a limited time, Pique is offering my community 12% off their fasting tea bundle plus an exclusive gift! So head on over to https://piquelife.com/dhru to redeem this exclusive offer today!