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Are you curious how GLP-1 and GIP hormones actually help you lose weight? In this video, Dr. Daniel Obi-Ofodile, MD provides the breaks down, the science behind these powerful incretin hormones for this conversation —and how they work together to reduce appetite, slow gastric emptying, and improve insulin response. Whether you’re exploring natural supplements, new medications, or just want to understand the biology behind weight loss, this explainer covers the essentials in a simple and engaging way. What you’ll learn: • What GLP-1 and GIP are • How they regulate hunger and metabolism • How they’re used in weight loss medications • Natural ways to support GLP-1 and GIP Resources: Download the free GLP-1 & GIP natural recipe at the bottom of this description. Link for the Natural products in this recipe. Arginine/citruline https://amzn.to/4j88BNc Astragulus https://amzn.to/3XAmyLz Forskohli https://amzn.to/3XzrZu4 Inulin/mountfit https://amzn.to/3Yalcar Turmeric https://amzn.to/4l3m0aS Liposomal Berberine https://amzn.to/4hS32RV Guarana https://amzn.to/4i9ijhv Alpha Lipoic acid https://amzn.to/4l72iuU Green Tea extract https://amzn.to/3FJQhLS MCT Oil https://amzn.to/4l72g6m Resveratrol https://amzn.to/3Y6ETQi Natural GLP-1 & GIP Support Formula – Liquid & Extract Forms Designed for ease of absorption and patient-friendly compliance Key Liquid/Extract-Based Ingredients & Benefits: • Berberine Extract (liquid tincture, 500 mg/day): Supports GLP-1 secretion and insulin sensitivity. • Curcumin Phytosome or Liquid Liposomal Curcumin (500–1000 mg/day): Improves absorption, supports GLP-1 modulation. • Inulin Syrup (prebiotic fiber, 5–10 g/day): Fermentable fiber increasing GLP-1 and gut microbiome health. • Forskolin Extract (Coleus forskohlii liquid, 250 mg/day): Stimulates GLP-1 secretion via cAMP activation. • EGCG from Green Tea Extract (liquid form, 300–400 mg/day): Enhances GLP-1 response, antioxidant support. • Alpha-Lipoic Acid (liquid R-ALA, 300–600 mg/day): Improves insulin action and glucose metabolism. • Hydrolyzed Whey Protein (liquid or ready-to-drink, 10–30 g/day): Increases both GLP-1 and GIP post-meal. • MCT Oil (liquid C8/C10, 5–10 mL/day): Stimulates GLP-1 and GIP via lipid-triggered gut hormone release. • Mangiferin/Resveratrol (liquid extract blend): Natural DPP-4 inhibitors that preserve incretin hormones. Suggested Use: Take extracts in divided doses with meals. Shake well and use as directed under practitioner guidance. Product Description: A liquid and extract-based formula to support natural GLP-1 and GIP function, enhance metabolic control, and promote healthy insulin response through bioavailable, easy-to-absorb plant and protein nutrients. References: 1. Nilsson M, et al. Am J Clin Nutr. 2004. (Whey protein and incretin release) 2. Steinert RE, et al. Am J Clin Nutr. 2011. (MCTs and gut hormone secretion) 3. Huang TH, et al. Phytomedicine. 2012. (Mangiferin as natural DPP-4 inhibitor) 4. Tolhurst G, et al. Diabetes. 2012. (SCFAs and incretin secretion) 5. Anand P, et al. Mol Pharm. 2007. (Bioavailability of curcumin formulations)
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Semaglutide is a GLP-1 agonist that's been around for a long time, suddenly Hollywood elites are now promoting it for fat loss. Here's the science you need to know. Support your fasting lifestyle with Berberine HCl & Alpha Lipoic Acid by by MYOXCIENCE Nutrition: https://bit.ly/berberine-biotin-ala-stack Use code Podcast to save Belly Fat Effect Book: https://amzn.to/3kBkySA Links to Studies: Posting soon -----------------------------------------Show Notes-------------------------------------- Best Low Carb Snacks: https://bit.ly/best-low-carb-snacks Best Sleep Mask: http://bit.ly/2AIVbDV Blue Blocking Glasses: http://bit.ly/blueblox Best Mouth Tape (Nexcare): https://amzn.to/31qJayh NeilMed Nasal Wash Kit https://amzn.to/3EUQaYE Breath Right Strips: https://amzn.to/31t5VSl A Metabolism Book Should Have:https://amzn.to/2jUiAh5 -----------------------------------------Show Notes-------------------------------------- 0:00 Intro 0:20 Semiglutide or Ozempic is a GLP-1 agonist. 0:30 GLP-1, glucagon like peptide 1, functions under the category of gastrointestinal incretin hormones that helps you process the foods you eat. It improves insulin sensitivity. Decreases glucagon. 1:30 About 80% of the mechanisms of bariatric surgery is by amplifying the release of incretin hormones. 2:00 There was a 14% loss of body weight in study participants. 2:50 Semiglutide aka Ozempic exerts stress on pancreatic beta cells, with an increased prevalence of pancreatitis and potentially pancreatic cancer. 4:40 GIP and GLP-1 are released after eating to increase insulin secretion from beta cells and prevent post-meal glucose excursions. 5:50 The diminished activity of GIP and GLP-1 is a feature of type-2 diabetes, beta cell insulin resistance, an obesity. 7:10 Exercise increases the release of gastrointestinal incretin hormones. 7:25 Berberine increases gut hormones and changes your microbiome. 7:40 These incretin hormones control the ecosystem of your gut microbiome and can improve function of immune cells around your gut. 8:10 Bifidobacterium can lead to a healthier GI incretin response. 9:00 GABA and L-glycine. 9:45 Protein and fat. 10:30 Polyphenols

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