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Weight loss is a common goal for many individuals, whether it be for health reasons or personal aesthetics. With the rise in obesity rates around the world, there has been a surge in research and development of medications that can aid in weight loss. Two medications that have gained attention in recent years are semaglutide and tirzepatide. Both medications have shown promising results in helping individuals lose weight, but which one is more effective?
Semaglutide
Semaglutide is a medication that belongs to a class of drugs known as GLP-1 receptor agonists. It works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) that is naturally produced by the body. This hormone helps to regulate blood sugar levels and appetite. Studies have shown that semaglutide can help individuals lose weight by reducing appetite and promoting feelings of fullness.
Semaglutide is typically administered as a subcutaneous injection once a week. It has been approved by the FDA for the treatment of obesity in individuals with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related comorbidity. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation.
Research has shown that individuals who take semaglutide can experience significant weight loss compared to those who take a placebo. In clinical trials, participants who took semaglutide lost an average of 15-20% of their body weight, making it a promising option for individuals struggling with obesity.
Tirzepatide
Tirzepatide is another medication that has shown promising results in aiding weight loss. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist. This means that it targets two different hormones that play a role in regulating blood sugar levels and appetite. Tirzepatide has been found to have a stronger effect on weight loss than other GLP-1 receptor agonists.
Unlike semaglutide, tirzepatide is administered as a subcutaneous injection once a week. It has been studied in individuals with obesity and type 2 diabetes, as well as in individuals without diabetes. Common side effects of tirzepatide include nausea, vomiting, diarrhea, and injection site reactions.
In clinical trials, tirzepatide has been shown to lead to significant weight loss in individuals with obesity. Participants who took tirzepatide lost an average of 10-15% of their body weight, making it a competitive option to consider for weight loss treatment.
Comparison
When comparing semaglutide and tirzepatide for weight loss, several factors should be taken into consideration. Semaglutide has been studied in individuals with obesity and has shown to lead to greater weight loss compared to tirzepatide. On the other hand, tirzepatide has been found to have a stronger effect on weight loss than other GLP-1 receptor agonists, including semaglutide.
Both medications have been associated with similar side effects, such as nausea, vomiting, and diarrhea. The choice between semaglutide and tirzepatide may depend on individual preferences, tolerability, and response to treatment. It is important to consult with a healthcare provider to determine the most suitable option for weight loss treatment.
In conclusion, both semaglutide and tirzepatide are promising medications for weight loss. They have shown to be effective in helping individuals lose weight and improve overall health. Further research is needed to determine the long-term effects and safety profile of these medications. In the meantime, individuals interested in weight loss treatment should discuss their options with a healthcare provider to make an informed decision.
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Mental health is super complicated. And many things, from your genetics to your environment, can affect it. But what you EAT might be having a big impact on your mental health, too. Hosted by: Hank Green ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at https://www.scishowtangents.org ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Sam Buck, Christopher R Boucher, Avi Yashchin, Adam Brainard, Greg, Alex Hackman, Sam Lutfi, D.A. Noe, Piya Shedden, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: https://academic.oup.com/ajcn/article/99/1/181/4577292 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127755/ https://www.sciencedirect.com/science/article/pii/S0261561401800224 https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/prospective-evaluation-of-the-depressionnutrient-intake-reverse-causality-hypothesis-in-a-cohort-of-communitydwelling-older-canadians/AB78CAE596A328F79EB19FEF9623FEEC https://www.sciencedirect.com/science/article/abs/pii/S0006322313004514 https://jech.bmj.com/content/61/7/631.short https://www.sciencedirect.com/science/article/abs/pii/S0920996413003617 https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/vitamin-d-deficiency-and-depression-in-adults-systematic-review-and-metaanalysis/F4E7DFBE5A7B99C9E6430AF472286860 https://www.sciencedirect.com/science/article/pii/S0163834317305868 https://onlinelibrary.wiley.com/doi/abs/10.1111/acps.12847 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429650/ https://www.sciencedirect.com/science/article/pii/S0308814606003049 https://www.ncbi.nlm.nih.gov/pubmed/20717016 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417078/ https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-11-200 https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-10-66 https://www.sciencedirect.com/science/article/pii/S0149763414001249?via%3Dihub https://www.sciencedirect.com/topics/medicine-and-dentistry/gut-microbiome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259177/ https://www.nature.com/articles/s41564-018-0337-x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365110/ https://onlinelibrary.wiley.com/doi/full/10.1002/wps.20672 https://guides.temple.edu/c.php?g=78618&p=4178695 https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262608/ https://www.ncbi.nlm.nih.gov/pubmed/29197739?dopt=Abstract Image Sources: https://www.istockphoto.com/photo/woman-biting-green-apple-gm1134557695-301519179 https://www.istockphoto.com/vector/valentines-day-dinner-seamless-pattern-gm1046207476-279939393 https://www.istockphoto.com/photo/close-up-the-vitamin-d-and-omega-3-fish-oil-capsules-supplement-on-wooden-plate-for-gm1166535212-321376714 https://commons.wikimedia.org/wiki/File:Acetylcysteine_3D.png https://www.istockphoto.com/photo/table-filled-with-large-variety-of-food-gm1155240408-314440450 https://www.videoblocks.com/video/clean-healthy-detox-eating-vegan-food-rhvp_gnw4jqh3lq4y
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Some people eat too much food. Others eat unhealthy food, perhaps because they cannot afford healthy alternatives. Other people continue to eat a balanced diet but still struggle with their weight. How we eat and how our bodies react to food greatly affects our health. More than a third of all deaths today are caused by diseases such as obesity and type 2 diabetes. But why does the body tell us that it wants more food – even though it has enough energy? And can you get the body to settle for what it needs by adjusting the body’s control systems? These questions have puzzled researchers for decades. And translating new knowledge into something to combat these diseases turned out to be extremely challenging. In the 1990s, as the obesity pandemic spreads, even young people start to lose their ability to keep their body weight and blood glucose in balance. In turn, researchers and pharmaceutical companies set out to find new remedies. Follow the Episode 1 "A diabetes doctor’s dream" of this year's Advent Calendar: The Story of GLP-1. 00:00:00 Introduction: Eating Habits and Health 00:00:14 Impact of Obesity and Type 2 Diabetes 00:00:28 Understanding Body's Hunger Signals 00:01:00 Efforts to Combat Obesity in the 1990s 00:01:40 Lotter’s Journey at Novo Nordisk 00:02:00 Challenges Faced by Novo Nordisk in the 1990s 00:02:50 Lotter's Mission and New Leadership 00:03:40 Discovering GLP-1 and Its Potential 00:04:40 Jens Reifeld’s Research Journey 00:05:20 Discovery of GLP-1's Role in Diabetes 00:06:40 Early Clinical Data and Challenges with GLP-1 00:07:30 Turning GLP-1 into a Viable Drug 00:08:10 Overcoming Obstacles and Future Directions
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F1 Keto Gummies are a popular weight loss supplement that has taken the dieting world by storm. These gummies are designed to help individuals achieve their weight loss goals by boosting their metabolism and promoting fat burning. With the F1 Keto Gummies, users can enjoy delicious gummies while reaping the benefits of a ketogenic diet.
Benefits of F1 Keto Gummies
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1. Ketosis: F1 Keto Gummies work by putting the body into a state of ketosis, where it burns fat for fuel instead of carbs. This can lead to rapid weight loss as the body uses stored fat for energy.
2. Fat Burning: The ingredients in F1 Keto Gummies are known for their ability to promote fat burning, especially in stubborn areas like the belly and thighs. By targeting stored fat, users can achieve a leaner and more toned physique.
3. Improved Digestion: These gummies also contain ingredients that support digestion, helping the body better absorb nutrients and eliminate waste. A healthy digestive system is essential for weight loss and overall well-being.
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1. Yes, F1 Keto Gummies are considered safe for most individuals when used as directed. However, it is always recommended to consult with a healthcare professional before starting any new supplement, especially if you have any underlying health conditions.
2. These gummies are made with natural ingredients and do not contain any harmful chemicals or additives. They are also gluten-free and suitable for vegans, making them a great choice for individuals with dietary restrictions.
3. While F1 Keto Gummies are generally safe, users may experience mild side effects such as digestive issues or headaches. These side effects are usually temporary and can be alleviated by drinking plenty of water and adjusting the dosage if needed.
Weightloss Day One
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