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Sticking to a healthy diet isn’t always easy, and it can feel almost impossible when you’re just starting out. While some may see this as a sign of weakness, today’s guest explains that our bodies simply haven’t evolved to keep up with modern lifestyles and the constant availability of ultra-processed foods. Today on The Dhru Purohit Show, Dhru sits down with Dr. Mike Israetel to discuss how our modern food environment taps into our evolutionary drive to consume and store calories for times of scarcity. Dr. Mike explains why punishing yourself or approaching weight loss with self-hatred is counterproductive and shares a practical guide for sustainable weight loss, no matter your goal. If you’re considering semaglutides, he outlines the key factors for a successful experience. Ready to crush your weight loss goals in 2025? Tune in for these expert tips! Dr. Mike, PhD, is the co-founder and Chief Content Officer of RP Strength (Renaissance Periodization) and the face of its popular YouTube channel. With a doctorate in sports physiology from East Tennessee State University, he is a seasoned expert in fitness and performance. As a former sports nutrition consultant for the U.S. Olympic Training Site in Johnson City, Tennessee, Dr. Mike has shared his expertise at global scientific and performance conferences, including seminars at the U.S. Olympic Training Center in Lake Placid. He has coached countless athletes in nutrition and weight training and continues to push his limits as a competitive bodybuilder and professional Brazilian Jiu-Jitsu grappler. In this episode, Dhru and Dr. Mike dive into: -Why the human body is good at storing fat and why it has been a key part of our survival as a species -Forgiveness and acceptance of your current body while empowering yourself to make changes -How to lose stubborn fat in a sustainable way -A balanced and practical approach to fat loss -The role of obesogens, calories, and seed oils in weight gain -Hidden calories in foods and how easily we overeat without realizing it -Weight loss and appetite-suppressing drugs -Key cultural and genetic differences in obesity levels between the USA, Japan, and other countries -Are semaglutides appropriate for individuals trying to lose less than 30 pounds -How diet can help reduce addictions -The difference between business meals and fun meals Also mentioned in this episode: For more on Dr. Mike, follow him on: -Instagram: https://www.instagram.com/rpstrength/ -X/Twitter: https://twitter.com/RPstrength -YouTube: https://www.youtube.com/@RenaissancePeriodization -Website:https://rpstrength.com/ Sponsors: https://dhrupurohit.com/sponsors/ This episode is brought to you by -Bon Charge: http://boncharge.com/DHRU -One Skin: http://oneskin.co -Cozy Earth: http://cozyearth.com/dhru Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

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Semaglutide, a drug originally developed to treat type 2 diabetes, has gained attention in recent years for its potential as a weight loss medication. Studies have shown that when used at higher doses, semaglutide can lead to significant weight loss in individuals with obesity. However, like any medication, there are concerns about the safety of using higher doses of semaglutide for weight loss. In this article, we will explore the maximum dose of semaglutide that is considered safe for weight loss and discuss the potential risks and benefits associated with its use.

The Maximum Dose of Semaglutide for Weight Loss

Semaglutide is currently approved by the FDA for the treatment of type 2 diabetes at a maximum dose of 1.0 mg once weekly. However, studies have shown that higher doses of semaglutide, up to 2.4 mg once daily, can lead to greater weight loss in individuals with obesity. The higher doses of semaglutide used for weight loss are not currently approved by the FDA, and the safety of long-term use at these doses is still being studied.

It is important for individuals considering using semaglutide for weight loss to consult with a healthcare provider to determine the most appropriate dosage. Healthcare providers will consider factors such as the individual’s current weight, overall health, and any existing medical conditions when determining the optimal dose of semaglutide for weight loss.

Potential Risks of High Doses of Semaglutide

While higher doses of semaglutide have been shown to be more effective for weight loss, there are potential risks associated with using the medication at these doses. Some common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects may be more severe at higher doses of the medication.

In addition to gastrointestinal side effects, there have been concerns about the potential cardiovascular risks associated with using semaglutide for weight loss. Some studies have suggested that semaglutide may increase the risk of certain cardiovascular events, such as heart attacks and strokes, especially in individuals with a history of cardiovascular disease.

Potential Benefits of Using Semaglutide for Weight Loss

Despite the potential risks, semaglutide has been shown to be an effective weight loss medication for many individuals. In addition to helping individuals lose weight, semaglutide can also improve other health markers, such as blood pressure, cholesterol levels, and blood sugar control.

Some studies have even suggested that using semaglutide for weight loss may help reduce the risk of developing type 2 diabetes in individuals who are at high risk for the disease. The medication works by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and promote weight loss.

Conclusion

In conclusion, while higher doses of semaglutide may be more effective for weight loss, it is important for individuals to use the medication under the guidance of a healthcare provider to minimize the potential risks. Before starting semaglutide for weight loss, individuals should discuss the benefits and risks of the medication with their healthcare provider and work together to determine the most appropriate dosage for their specific needs.

Overall, semaglutide shows promise as a weight loss medication, but more research is needed to fully understand the long-term safety and effectiveness of using the medication at higher doses. Individuals interested in using semaglutide for weight loss should stay informed about the latest research and consult with their healthcare provider to make informed decisions about their treatment plan.

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Welcome to my channel! I'm Mandy, a 50-year-old on a journey to better health. I've lost nearly 10 kilos in 9 weeks with the help of Mounjaro, and I share my experiences, tips, and updates to inspire and connect with others on similar journeys. In this video, I demonstrate how I take my weekly Mounjaro injection, recap my progress, discuss my dosing strategy, share highlights and challenges from the past year, and reflect on how this journey is transforming my life. If you're curious about Mounjaro, balancing weight loss with life, or just here for inspiration, you’re in the right place. Don’t forget to like, comment, and subscribe to join me on this journey. Let's thrive together in 2025! Disclaimer: I’m not a doctor or healthcare professional. This is my personal experience with weight loss and Mounjaro. Please consult your doctor for medical advice. #WeightLossJourney #Mounjaro #LifeAfter50 #mounjaro #mounjaroweightloss #tirzepatide #mounjaro #tirzepatide #mounjaroweightloss #mounjaro #mounjaroweightloss #glp1 #mounjaroweightloss #mounjaro #tirzepatide #weightlossjourney #tirzepatide #weightloss #glp1forweightloss

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In this video, we dive into a study exploring the best methods to maintain weight loss after a low-calorie diet. Participants followed an 8-week low-calorie plan, losing around 13 kg, then split into groups: exercise, liraglutide, combined exercise + liraglutide, and a placebo. Results revealed that the combination approach led to the most weight loss, while exercise alone boosted fitness and muscle retention. Each method had unique benefits and some side effects, helping viewers understand which approach might work best. For tailored weight-loss support, contact our clinic at 571 Union Ave, Framingham, MA, or call us at 508-820-8332. 📌 Disclaimer: This video is for informational purposes only and not a substitute for medical advice. Always consult a healthcare provider before starting any treatment.