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In episode 197 of the Thyroid Answers podcast, I discuss GLP-1 with Jeff Thurston. In this episode, we discuss: - Where GLP-1 is made in the body - What GLP-1 does in the body. - The role of GI bacteria in GLP-1 production. - The role of diet in GLP-1 production. - The role of lifestyle on gut flora balance and GLP-1 production. - The role of probiotics - Strategies for improving gut bacteria and natural GLP-1 production - And more... Jeff is the co-owner of Master Supplements and US Enzymes. He has a degree in biology and chemistry. He began his career as a virologist under a government security clearance, working with extremely virulent pathogens. As he grew to understand the purpose of the work, he left to begin a career in sales and sales management. While working in organic agriculture in the Central Valley of CA, he met Randy Porubcan. Both were speakers at a meeting. Being of similar age, similar backgrounds, college in the upper midwest, they hit it off. That was in 1995. Randy suggested they start a business one day. In 2002, Randy called Jeff and asked if he was ready. He said yes, and they started their business, Master Supplements. In September of 2019, they purchased US Enzymes, adding a product line of highly efficacious enzyme supplements to their line of probiotics. Jeff can be found at: usenzymes.com https://master-supplements.com Previous episode with Jeff Thurston: TAP 84: Introduction to Probiotics

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Serotonin is a neurotransmitter that plays a crucial role in regulating mood, appetite, and sleep. It is often referred to as the “feel-good” chemical because it contributes to feelings of well-being and happiness. Recent research has shown that serotonin also plays a role in weight regulation, with low levels of serotonin being associated with weight gain and obesity.

Semaglutide is a medication that has been approved by the FDA for the treatment of obesity. It works by mimicking the effects of a hormone called GLP-1, which helps to regulate blood sugar levels and appetite. By increasing the levels of GLP-1 in the body, semaglutide can help to reduce appetite and promote weight loss.

The combination of serotonin and semaglutide in weight loss treatment has shown promising results in clinical trials. These serotonin centers focus on the role of serotonin in regulating appetite and mood, while semaglutide helps to target the physiological aspects of weight loss. By addressing both the psychological and physiological aspects of obesity, this treatment approach offers a comprehensive solution for individuals struggling with obesity.

Role of Serotonin in Weight Regulation

Serotonin is a neurotransmitter that is involved in a wide range of physiological processes, including mood regulation, appetite control, and sleep. It is produced in the brain and the gut, and plays a critical role in modulating the communication between the brain and the digestive system. Low levels of serotonin have been linked to increased appetite, cravings for high-calorie foods, and emotional eating. By targeting serotonin receptors in the brain, medications like semaglutide can help to restore the balance of this important neurotransmitter and promote weight loss.

Research has shown that serotonin plays a key role in the regulation of appetite and food intake. Serotonin receptors are found in areas of the brain that are involved in controlling hunger and satiety, and serotonin signaling helps to signal feelings of fullness and satisfaction after a meal. By increasing serotonin activity in the brain, medications like semaglutide can help to reduce cravings and promote a sense of fullness, making it easier for individuals to stick to a healthy diet and achieve their weight loss goals.

In addition to its role in appetite regulation, serotonin also plays a critical role in mood regulation. Low levels of serotonin have been linked to symptoms of depression and anxiety, which are common in individuals struggling with obesity. By targeting serotonin receptors in the brain, medications like semaglutide can help to improve mood and emotional well-being, making it easier for individuals to stay motivated and committed to their weight loss journey.

Benefits of Semaglutide in Weight Loss Treatment

Semaglutide is a medication that belongs to a class of drugs called GLP-1 receptor agonists. GLP-1 is a hormone that is produced in the gut in response to food intake, and plays a key role in regulating blood sugar levels and appetite. By mimicking the effects of GLP-1, semaglutide helps to reduce appetite, promote feelings of fullness, and regulate blood sugar levels. This can lead to significant weight loss in individuals who are struggling with obesity.

Clinical trials have shown that semaglutide is highly effective in promoting weight loss in individuals with obesity. In one study, participants who were treated with semaglutide lost an average of 14% of their body weight over a 68-week period. This level of weight loss is significantly greater than what is typically achieved with diet and exercise alone, making semaglutide a valuable tool in the treatment of obesity.

In addition to its weight loss benefits, semaglutide has also been shown to have a number of other health benefits. Studies have shown that semaglutide can help to improve blood sugar control, reduce the risk of cardiovascular disease, and improve overall quality of life in individuals with obesity. By addressing both the physical and psychological aspects of obesity, semaglutide offers a comprehensive treatment approach that can help individuals achieve long-term success in their weight loss journey.

Combining Serotonin and Semaglutide for Optimal Weight Loss

The combination of serotonin and semaglutide in weight loss treatment offers a unique approach that addresses both the physiological and psychological factors that contribute to obesity. By targeting serotonin receptors in the brain, medications like semaglutide can help to regulate appetite and reduce cravings for high-calorie foods. At the same time, semaglutide helps to promote weight loss by mimicking the effects of GLP-1 and regulating blood sugar levels.

By combining these two approaches, individuals with obesity can benefit from a comprehensive treatment plan that addresses the root causes of their weight gain. This dual-action approach not only helps to promote weight loss, but also helps to improve mood, reduce cravings, and increase motivation. This can make it easier for individuals to stick to a healthy diet and exercise plan, leading to sustainable weight loss and improved overall health.

In conclusion, serotonin centers that utilize semaglutide in weight loss treatment offer a promising solution for individuals struggling with obesity. By addressing the role of serotonin in appetite regulation and mood control, while also harnessing the weight loss benefits of semaglutide, these centers provide a comprehensive approach to weight loss that can help individuals achieve long-term success in their journey towards better health.

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New research shows GLP-1 agonists, like Ozempic, and SGLT2 inhibitors, like Farxiga, help lower the risk of secondary stroke, heart attack and death in stroke survivors. https://www.healthday.com/healthday-tv/neurology/popular-diabetes-and-weight-loss-drugs-may-protect-stroke-survivors-from-future-attacks-study-finds Popular medications commonly prescribed for type 2 diabetes and weight loss may protect stroke patients from future attacks. A quarter of people who survive a stroke have a secondary stroke or heart attack, according to researchers. In a new study, they looked at whether GLP-1 agonists and another class of drugs called SGLT2 inhibitors decrease these risks. GLP-1s include drugs such as Ozempic, and SGLT2s include drugs like Farxiga and Jardiance. The researchers reviewed medical records for more than 7,000 adults who experienced an ischemic stroke and the results showed participants prescribed either class of medication after their initial stroke had a 74% lower risk of death and an 84% lower risk of heart attack within an average of three years. SGLT2 drugs were also associated with 67% lower odds of a second stroke. The lead investigator says, “The results of the study are consistent with other research about the preventive role of these medications against cardiovascular disease in people with obesity or heart failure." The study also showed that GLP-1 medications may help lower the risk of clotting, which is a major cause of stroke. Clinical trials are now needed to confirm the findings. Source: American Heart Association Scientific Sessions Author Affiliations: Mayo Clinic, Wake Forest University School of Medicine Image Attribution: Adobe Stock Visit HealthDay.com: https://healthday.com Like HealthDay on Facebook: https://www.facebook.com/HealthDayNews Follow HealthDay on Instagram: https://www.instagram.com/healthday_news Follow HealthDay on Twitter: https://twitter.com/HealthDayTweets Connect with HealthDay on LinkedIn: https://www.linkedin.com/company/418188/ #StrokePrevention, #GLP1Agonists, #SGLT2Inhibitors, #Ozempic, #Farxiga, #Jardiance, #HeartAttackPrevention, #CardiovascularHealth, #StrokeSurvivors, #SecondaryStrokePrevention, #Type2Diabetes, #ObesityManagement, #CardiovascularBenefits, #StrokeRiskReduction, #MedicationOptions, #ClinicalTrials, #HeartDiseasePrevention, #StrokePreventionResearch, #CardiovascularOutcomes, #StrokePreventionGuidelines, #MedicationForSeniors, #StrokeRecovery, #StrokeAwareness, #HealthInnovation, #MedicalResearch, #DiabetesManagement, #WeightLossMedication, #HeartHealth, #StrokeEducation, #PreventiveMedicine #HealthNews #HealthAdvice #HealthTips #HealthyLiving #HealthyHabits #HealthyLifestyle #HealthyChoices #Wellness #WellnessTips #MedicalResearch #MedicalStudy #HealthResearch #HealthStudies #WellnessMatters #StayHealthy #HealthRisks #MedicalAdvice #HealthAwareness #HealthDiscussion #HealthStudy #ResearchFindings #HealthSolutions #HealthEducation #HealthInformation #MedicalFindings #ScienceNews #HealthData #ScientificFindings #MedicalNews

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