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Breaking News on GLP-1 Medications: Weight Loss, Manufacturing Advances, and Health Benefits In this episode of the Downsized News, hosts Laraine and Christopher Durham dive into the latest breakthroughs and updates on GLP-1 medications, Zepbound, Mounjaro, Ozempic, Wegovy, Compounded tripeptide, and compounded semaglutide. The discussion highlights Eli Lilly's $3 billion investment to ramp up production and reveals new findings on the potential benefits of GLP-1s in reducing dementia risk and improving inflammatory bowel disease outcomes. The duo, having personally lost significant weight with GLP-1s, emphasizes the importance of consulting a healthcare professional before starting any medication. The script also covers Eli Lilly’s manufacturing expansion, the American Diabetes Association's stance on compounded GLP-1s, and promising studies showing GLP-1s' effectiveness in treating obesity and related conditions. Compounded medications' role in healthcare and the potential acquisition of Catalent by Novo Holdings are also discussed, showcasing the vast impact on pharmaceutical manufacturing and patient accessibility. Join the Downsize community as they explore what these developments mean for GLP-1 users. REFERENCES ADA’s Stance on Compounded GLP-1 Medications: A Predictable Take https://diabetesjournals.org/care/article/doi/10.2337/dci24-0091/157478/Compounded-GLP-1-and-Dual-GIP-GLP-1-Receptor IBD Research: https://academic.oup.com/ecco-jcc/advance-article-abstract/doi/10.1093/ecco-jcc/jjae160/7833454?redirectedFrom=fulltext We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store 00:00 Introduction 00:29 Welcome to The Downsized News 00:46 GLP-1 Medications Overview 01:28 Eli Lilly's Big Win with Zepbound 02:54 Eli Lilly's $3 Billion Expansion 06:16 ADA's Stance on Compounded GLP-1s 10:36 GLP-1s and Inflammatory Bowel Disease 13:37 Novo Holdings' New Obesity Treatment 16:28 APC's Fight for Compounded Semaglutide 19:18 Novo Holdings Acquires Catalent 22:59 Conclusion and Wrap-Up

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The Role of Microdosing GLP-1 Semaglutide for Weight Loss and Other Health Benefits. Exploring the frequency and goals of microdosing #Microdosing #GLP1 #semaglutide #healthjourney #healthresearch #biohack #longevity #weightloss Microdosing GLP-1 semaglutide is a technique that involves taking small, sub-therapeutic doses of the drug to achieve specific health goals. GLP-1 (glucagon-like peptide-1) is a hormone that helps regulate blood sugar levels and promotes insulin release. Semaglutide is a medication that mimics the effects of GLP-1 and is commonly used in the treatment of type 2 diabetes. The frequency and goals of microdosing GLP-1 semaglutide vary depending on the individual's specific health needs. Some people may choose to microdose on a daily basis, while others may choose to do it a few times per week. The goal of microdosing is typically to enhance the benefits of GLP-1 semaglutide while minimizing potential side effects. One common goal of microdosing is weight management. GLP-1 semaglutide has been shown to reduce appetite and promote feelings of fullness, leading to weight loss in individuals with obesity. Microdosing can help individuals achieve a lower daily dose of the medication while still getting the desired weight loss effects. Another goal of microdosing is to manage blood sugar levels and improve insulin sensitivity. GLP-1 semaglutide can help regulate glucose metabolism in individuals with diabetes, leading to better blood sugar control. Microdosing may be used to maintain stable blood sugar levels without the need for higher doses of the medication. There is also research exploring the potential benefits of microdosing GLP-1 semaglutide for other health conditions. For example, studies have shown that GLP-1 semaglutide may have cardiovascular benefits by reducing the risk of heart disease and stroke. Microdosing could be used as a way to potentially access these benefits while minimizing the risks associated with higher doses. Overall, microdosing GLP-1 semaglutide can be a useful technique for individuals looking to achieve specific health goals while using lower doses of the medication. It is important to consult with a healthcare professional before starting microdosing to ensure it is appropriate and safe for your individual health journey.

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